AT331398B - Verfahren zur herstellung von stabilen suspensionen von lebensfahigen viren - Google Patents

Verfahren zur herstellung von stabilen suspensionen von lebensfahigen viren

Info

Publication number
AT331398B
AT331398B AT98274A AT98274A AT331398B AT 331398 B AT331398 B AT 331398B AT 98274 A AT98274 A AT 98274A AT 98274 A AT98274 A AT 98274A AT 331398 B AT331398 B AT 331398B
Authority
AT
Austria
Prior art keywords
vivid
viruses
producing stable
stable suspensions
suspensions
Prior art date
Application number
AT98274A
Other languages
German (de)
English (en)
Other versions
ATA98274A (de
Original Assignee
Rit Rech Ind Therapeut
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rit Rech Ind Therapeut filed Critical Rit Rech Ind Therapeut
Publication of ATA98274A publication Critical patent/ATA98274A/de
Application granted granted Critical
Publication of AT331398B publication Critical patent/AT331398B/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/245Herpetoviridae, e.g. herpes simplex virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5254Virus avirulent or attenuated
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/16011Herpesviridae
    • C12N2710/16311Mardivirus, e.g. Gallid herpesvirus 2, Marek-like viruses, turkey HV
    • C12N2710/16334Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/16011Herpesviridae
    • C12N2710/16311Mardivirus, e.g. Gallid herpesvirus 2, Marek-like viruses, turkey HV
    • C12N2710/16351Methods of production or purification of viral material
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/16011Herpesviridae
    • C12N2710/16711Varicellovirus, e.g. human herpesvirus 3, Varicella Zoster, pseudorabies
    • C12N2710/16734Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/16011Herpesviridae
    • C12N2710/16711Varicellovirus, e.g. human herpesvirus 3, Varicella Zoster, pseudorabies
    • C12N2710/16751Methods of production or purification of viral material

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Public Health (AREA)
  • Zoology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Mycology (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT98274A 1973-02-09 1974-02-07 Verfahren zur herstellung von stabilen suspensionen von lebensfahigen viren AT331398B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US330912A US3915794A (en) 1973-02-09 1973-02-09 Stabilizing compositions for cell-free viruses and cell-free virus preparations containing them

Publications (2)

Publication Number Publication Date
ATA98274A ATA98274A (de) 1975-11-15
AT331398B true AT331398B (de) 1976-08-25

Family

ID=23291840

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98274A AT331398B (de) 1973-02-09 1974-02-07 Verfahren zur herstellung von stabilen suspensionen von lebensfahigen viren

Country Status (18)

Country Link
US (1) US3915794A (en, 2012)
JP (1) JPS5732043B2 (en, 2012)
AT (1) AT331398B (en, 2012)
BE (1) BE810555A (en, 2012)
CA (1) CA1035700A (en, 2012)
CH (1) CH592143A5 (en, 2012)
DD (1) DD110306A5 (en, 2012)
DE (1) DE2406167C2 (en, 2012)
DK (1) DK134032B (en, 2012)
ES (1) ES422961A1 (en, 2012)
FR (1) FR2216997B1 (en, 2012)
GB (1) GB1452344A (en, 2012)
HU (1) HU169120B (en, 2012)
IE (1) IE38825B1 (en, 2012)
IL (1) IL44011A (en, 2012)
NL (1) NL178013C (en, 2012)
SE (1) SE427799B (en, 2012)
ZA (1) ZA74163B (en, 2012)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT71926B (en) * 1979-10-29 1982-03-31 Merck & Co Inc Process for preparing a liquid vaccine comprising a stabilizer
JPS57114527A (en) * 1979-10-29 1982-07-16 Merck & Co Inc Vaccine stabilizer
US4273762A (en) * 1979-12-03 1981-06-16 Merck & Co., Inc. Lyophilization process for live viral compositions
JPS59163313A (ja) * 1983-03-09 1984-09-14 Teijin Ltd 経鼻投与用ペプチドホルモン類組成物
ZA874625B (en) * 1986-06-30 1988-10-26 Smith Kline Rit Stabilizers for live vaccines,process for their preparation and vaccines containing them
US4847078A (en) * 1987-01-14 1989-07-11 Arseco, Inc. Storage stable topical composition having moisture control agent
JPH01112853U (en, 2012) * 1988-01-27 1989-07-28
US5045446A (en) * 1988-08-26 1991-09-03 Cryopharm Corporation Lyophilization of cells
IL90188A0 (en) * 1988-05-18 1989-12-15 Cryopharm Corp Process and medium for the lyophilization of erythrocytes
EP0484519A4 (en) * 1990-05-25 1993-12-29 Cryopharm Corporation Process for lyophilizing cells, cell-like materials and platelets in a mixture of biocompatible amphipathic polymers
CA2075521C (en) * 1992-05-05 1995-11-28 Kuniaki Koyama Stabilized live vaccine
US5607852A (en) * 1992-06-04 1997-03-04 Merch & Co., Inc. Process for attenuated varicella zoster virus vaccine production
US5360736A (en) * 1992-06-04 1994-11-01 Merck & Co., Inc. Process for attenuated varicella zoster virus vaccine production
WO1995010601A1 (en) * 1993-10-12 1995-04-20 Chiron Viagene, Inc. Methods for preserving recombinant viruses
CA2252565C (en) * 1996-04-26 2010-11-23 David B. Volkin Dna vaccine formulations
ZA973642B (en) * 1996-04-26 1997-11-25 Merck & Co Inc DNA vaccine formulations.
US6051238A (en) * 1996-12-20 2000-04-18 Merck & Co., Inc. Stabilizers for lyophilized mumps vaccines
US6210683B1 (en) 1997-09-05 2001-04-03 Merck & Co., Inc. Stabilizers containing recombinant human serum albumin for live virus vaccines
DE19812940A1 (de) * 1998-03-24 1999-10-07 Medigene Ag Formulierung mit Papillomavirus-spezifischem Protein, seine Herstellung und Verwendung
US6926897B1 (en) * 1998-03-24 2005-08-09 Medigene Aktiengesellschaft Medicament for the avoidance or treatment of papillomavirus-specific tumour
GB9808922D0 (en) * 1998-04-24 1998-06-24 Cantab Pharmaceuticals Res Ltd Virus preparations
US6225289B1 (en) 1998-12-10 2001-05-01 Genvec, Inc. Methods and compositions for preserving adenoviral vectors
RU2144376C1 (ru) * 1999-06-28 2000-01-20 Всероссийский научно-исследовательский институт защиты животных Сухая вирусвакцина против болезни марека и способ ее изготовления
RU2144378C1 (ru) * 1999-06-28 2000-01-20 Всероссийский научно-исследовательский институт защиты животных Вирусвакцина против болезни марека и способ ее изготовления
FR2814957B1 (fr) 2000-10-06 2002-12-20 Aventis Pasteur Composition vaccinale et procede de stabilisation
US7013940B2 (en) * 2001-04-19 2006-03-21 Michelin Recherche Et Technique S.A. Device for attenuating cavity noise in a tire and wheel
ES2247414T3 (es) * 2001-12-10 2006-03-01 Bavarian Nordic A/S Composiciones que contienen poxvirus y procedimiento para su preparacion.
TWI398272B (zh) * 2005-03-08 2013-06-11 Intervet Int Bv 化學定義的安定劑
EP1870649A1 (en) * 2006-06-20 2007-12-26 Octapharma AG Lyophilisation targetting defined residual moisture by limited desorption energy levels
EA031229B1 (ru) 2011-08-12 2018-12-28 Мериал, Инк. Способ витрификации биологического материала
TWI690322B (zh) * 2012-10-02 2020-04-11 法商傳斯堅公司 含病毒的調配物及其使用
WO2015175672A1 (en) 2014-05-14 2015-11-19 Merial, Inc. Methods for freeze-drying and rehydrating biologics
AU2015357225B2 (en) * 2014-12-01 2020-04-09 Transgene Sa Stable liquid vaccinia virus formulations
CN105999287A (zh) * 2016-07-01 2016-10-12 广东圣戈生物科技有限公司 一种疫苗稀释液及其制备方法
AU2017339971B2 (en) 2016-10-05 2023-03-02 Zoetis Services Llc Lyophilization methods that provide stably dehydrated protozoans for use as potent live vaccines
US20200308550A1 (en) 2017-09-11 2020-10-01 Imba - Institut Für Molekulare Biotechnologie Gmbh Tumor organoid model

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1292803A (en) * 1968-11-18 1972-10-11 Nat Res Dev Improvements relating to the production of antigens
US3642574A (en) * 1970-04-29 1972-02-15 Us Agriculture Method for producing vaccine for immunization of poultry against marek{3 s disease
US3783098A (en) * 1971-08-10 1974-01-01 Cornell Res Foundation Inc Highly potent,viable and stable cellfree virus preparations from cells infected with cell-associated viruses and method for obtaining the same

Also Published As

Publication number Publication date
BE810555A (fr) 1974-08-05
IL44011A (en) 1977-04-29
DK134032C (en, 2012) 1977-02-07
IE38825B1 (en) 1978-06-07
IE38825L (en) 1974-08-09
DK134032B (da) 1976-08-30
NL178013B (nl) 1985-08-01
SE427799B (sv) 1983-05-09
DD110306A5 (en, 2012) 1974-12-12
CA1035700A (en) 1978-08-01
FR2216997A1 (en, 2012) 1974-09-06
US3915794A (en) 1975-10-28
CH592143A5 (en, 2012) 1977-10-14
AU6486574A (en) 1975-07-24
DE2406167C2 (de) 1984-12-20
FR2216997B1 (en, 2012) 1978-01-06
DE2406167A1 (de) 1974-08-15
GB1452344A (en) 1976-10-13
NL178013C (nl) 1986-01-02
ES422961A1 (es) 1976-06-01
NL7401786A (en, 2012) 1974-08-13
JPS5732043B2 (en, 2012) 1982-07-08
JPS49109518A (en, 2012) 1974-10-18
ATA98274A (de) 1975-11-15
HU169120B (en, 2012) 1976-09-28
ZA74163B (en) 1974-11-27
IL44011A0 (en) 1974-05-16

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Legal Events

Date Code Title Description
ELJ Ceased due to non-payment of the annual fee
REN Ceased due to non-payment of the annual fee