AT330180B - Verfahren zur herstellung von neuen benzo-(ij)-chinolizinderivaten und ihren salzen - Google Patents

Verfahren zur herstellung von neuen benzo-(ij)-chinolizinderivaten und ihren salzen

Info

Publication number
AT330180B
AT330180B AT277074A AT277074A AT330180B AT 330180 B AT330180 B AT 330180B AT 277074 A AT277074 A AT 277074A AT 277074 A AT277074 A AT 277074A AT 330180 B AT330180 B AT 330180B
Authority
AT
Austria
Prior art keywords
chinolicine
derivatives
salt
preparation
new benzo
Prior art date
Application number
AT277074A
Other languages
German (de)
English (en)
Other versions
ATA277074A (de
Inventor
Gwynn Pennant Ellis
Heulwen Moira Ridgway
David Edmund Bays
Original Assignee
Allen & Hanburys Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Allen & Hanburys Ltd filed Critical Allen & Hanburys Ltd
Publication of ATA277074A publication Critical patent/ATA277074A/de
Application granted granted Critical
Publication of AT330180B publication Critical patent/AT330180B/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/04Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to the ring carbon atoms
    • C07D215/06Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to the ring carbon atoms having only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached to the ring nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D455/00Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
    • C07D455/03Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
    • C07D455/04Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing a quinolizine ring system condensed with only one six-membered carbocyclic ring, e.g. julolidine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT277074A 1973-04-05 1974-04-03 Verfahren zur herstellung von neuen benzo-(ij)-chinolizinderivaten und ihren salzen AT330180B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB1627973A GB1433151A (en) 1973-04-05 1973-04-05 Benzo-ij-quinolizines

Publications (2)

Publication Number Publication Date
ATA277074A ATA277074A (de) 1975-09-15
AT330180B true AT330180B (de) 1976-06-25

Family

ID=10074459

Family Applications (1)

Application Number Title Priority Date Filing Date
AT277074A AT330180B (de) 1973-04-05 1974-04-03 Verfahren zur herstellung von neuen benzo-(ij)-chinolizinderivaten und ihren salzen

Country Status (14)

Country Link
US (1) US3917608A (e)
JP (1) JPS5024296A (e)
AT (1) AT330180B (e)
AU (1) AU6720074A (e)
BE (1) BE813158A (e)
CA (1) CA1015758A (e)
CH (1) CH602722A5 (e)
DE (1) DE2415763A1 (e)
FR (1) FR2230355B1 (e)
GB (1) GB1433151A (e)
IE (1) IE39101B1 (e)
LU (1) LU69756A1 (e)
NL (1) NL7404719A (e)
ZA (1) ZA741860B (e)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT377987B (de) * 1979-04-11 1985-05-28 Otsuka Pharma Co Ltd Verfahren zur herstellung von neuen piperazinylbenzoheterozyklischen verbindungen und ihren pharmazeutisch annehmbaren salzen
AT377986B (de) * 1978-08-31 1985-05-28 Otsuka Pharma Co Ltd Verfahren zur herstellung von neuen piperazinylbenzoheterozyklischen verbindungen und ihren pharmazeutisch annehmbaren salzen

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4051247A (en) * 1975-04-14 1977-09-27 Riker Laboratories, Inc. Method of using 7-hydroxy-benzo[ij]quinolizine-2-carboxylic acid derivatives
JPS5540616A (en) * 1978-09-14 1980-03-22 Otsuka Pharmaceut Co Ltd Preparation of benzo-hetero-compound
US4400386A (en) * 1981-11-06 1983-08-23 Riker Laboratories, Inc. Antimicrobial derivatives of 8-amino and 8-aminomethyl benzo(ij)quinolizine
US4472407A (en) * 1983-03-17 1984-09-18 Riker Laboratories, Inc. Antimicrobial 8-alkoxy-6,7-dihydro-5-methyl-9-fluoro-1-oxo-1H,5H-benzo[ij]qu
US4650804A (en) * 1984-03-30 1987-03-17 Fujisawa Pharmaceutical Co., Ltd. Quinolizinone compounds and pharmaceutical composition comprising the same, useful as anti-ulcerative and anti-allergic agents
CA1266484A (en) * 1984-12-14 1990-03-06 Ronald Edward Mac Leay Tert-octylhydrazine, its salts and derivatives
DE3519926A1 (de) * 1985-06-04 1986-12-04 Bayer Ag Indolinderivate, verfahren zu ihrer herstellung und diese indolinderivate enthaltende kosmetische lichtschutzmittel
EP0882046A1 (en) * 1996-02-21 1998-12-09 Darwin Discovery Limited Quinolones and their therapeutic use
US5792774A (en) * 1996-02-21 1998-08-11 Chiroscience Limited Quinolones and their therapeutic use
AU710876B2 (en) * 1996-02-21 1999-09-30 Darwin Discovery Limited Quinolones and their therapeutic use
US20100074949A1 (en) 2008-08-13 2010-03-25 William Rowe Pharmaceutical composition and administration thereof
RU2528046C2 (ru) * 2004-06-24 2014-09-10 Вертекс Фармасьютикалз Инкорпорейтед Модуляторы транспортеров атф-связывающей кассеты
ES2656017T3 (es) 2004-06-24 2018-02-22 Vertex Pharmaceuticals Incorporated Moduladores de transportadores del casete de unión a ATP
US8354427B2 (en) 2004-06-24 2013-01-15 Vertex Pharmaceutical Incorporated Modulators of ATP-binding cassette transporters
EP2502912A3 (en) * 2004-06-24 2013-11-06 Vertex Pharmaceuticals Incorporated Modulators of ATP-binding cassette transporters
DK3219705T3 (da) 2005-12-28 2020-04-14 Vertex Pharma Farmaceutiske sammensætninger af den amorfe form af n-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinolin-3-carboxamid
EP3330255B1 (en) 2009-03-20 2020-12-09 Vertex Pharmaceuticals Incorporated Process for making modulators of cystic fibrosis transmembrane conductance regulator
US8802700B2 (en) 2010-12-10 2014-08-12 Vertex Pharmaceuticals Incorporated Modulators of ATP-Binding Cassette transporters
AU2013226076B2 (en) 2012-02-27 2017-11-16 Vertex Pharmaceuticals Incorporated Pharmaceutical composition and administration thereof
JP6746569B2 (ja) 2014-10-07 2020-08-26 バーテックス ファーマシューティカルズ インコーポレイテッドVertex Pharmaceuticals Incorporated 嚢胞性線維症膜貫通コンダクタンス制御因子のモジュレーターの共結晶

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3728350A (en) * 1967-07-17 1973-04-17 Lilly Co Eli 1-(2-carboxyphenyl)-5,7-dimethoxy-3,4-dihydrocarbostyril intermediates for acronycis
US3793328A (en) * 1969-11-03 1974-02-19 Upjohn Co 8benzoyl 1,2,3,4 tetrahydroquinoline
BE789822A (fr) * 1971-10-08 1973-04-06 Allen & Hanburys Ltd Nouveaux composes heterocycliques
BE793524A (fr) * 1971-12-30 1973-06-29 Riker Laboratories Inc Acides benzoquinolizine-carboxyliques et leurs derives

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT377986B (de) * 1978-08-31 1985-05-28 Otsuka Pharma Co Ltd Verfahren zur herstellung von neuen piperazinylbenzoheterozyklischen verbindungen und ihren pharmazeutisch annehmbaren salzen
AT377987B (de) * 1979-04-11 1985-05-28 Otsuka Pharma Co Ltd Verfahren zur herstellung von neuen piperazinylbenzoheterozyklischen verbindungen und ihren pharmazeutisch annehmbaren salzen

Also Published As

Publication number Publication date
LU69756A1 (e) 1975-06-16
NL7404719A (e) 1974-10-08
DE2415763A1 (de) 1974-10-17
CA1015758A (en) 1977-08-16
AU6720074A (en) 1975-10-02
FR2230355B1 (e) 1977-05-06
BE813158A (fr) 1974-10-01
FR2230355A1 (e) 1974-12-20
ZA741860B (en) 1975-02-26
IE39101B1 (en) 1978-08-02
CH602722A5 (e) 1978-07-31
GB1433151A (en) 1976-04-22
US3917608A (en) 1975-11-04
JPS5024296A (e) 1975-03-15
IE39101L (en) 1974-10-05
ATA277074A (de) 1975-09-15
AU474838B2 (e) 1976-08-05

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Legal Events

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ELA Expired due to lapse of time