AT315831B - Verfahren zur Herstellung von neuen 4-Aza-benzimidazolderivaten und ihren Salzen - Google Patents

Verfahren zur Herstellung von neuen 4-Aza-benzimidazolderivaten und ihren Salzen

Info

Publication number
AT315831B
AT315831B AT748871A AT748871A AT315831B AT 315831 B AT315831 B AT 315831B AT 748871 A AT748871 A AT 748871A AT 748871 A AT748871 A AT 748871A AT 315831 B AT315831 B AT 315831B
Authority
AT
Austria
Prior art keywords
aza
salts
preparation
new
benzimidazole derivatives
Prior art date
Application number
AT748871A
Other languages
German (de)
English (en)
Original Assignee
Degussa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to BE788065D priority Critical patent/BE788065A/xx
Application filed by Degussa filed Critical Degussa
Priority to AT748871A priority patent/AT315831B/de
Priority to DD164684A priority patent/DD99580A5/xx
Priority to YU2041/72A priority patent/YU34897B/xx
Priority to IL40080A priority patent/IL40080A/xx
Priority to CH1201872A priority patent/CH592660A5/xx
Priority to SU1821216A priority patent/SU557758A3/ru
Priority to ES405982A priority patent/ES405982A1/es
Priority to NL7211407A priority patent/NL7211407A/xx
Priority to FR7229915A priority patent/FR2150820B1/fr
Priority to DE2241575A priority patent/DE2241575A1/de
Priority to GB3940272A priority patent/GB1397645A/en
Priority to ZA725868A priority patent/ZA725868B/xx
Priority to BR5845/72A priority patent/BR7205845A/pt
Priority to HUDE789A priority patent/HU166382B/hu
Priority to AU45981/72A priority patent/AU461671B2/en
Priority to CA150,204A priority patent/CA979907A/en
Priority to JP47085203A priority patent/JPS4832898A/ja
Priority to AR243765A priority patent/AR199879A1/es
Application granted granted Critical
Publication of AT315831B publication Critical patent/AT315831B/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62Oxygen or sulfur atoms
    • C07D213/63One oxygen atom
    • C07D213/64One oxygen atom attached in position 2 or 6
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/73Unsubstituted amino or imino radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/74Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/75Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT748871A 1971-08-26 1971-08-26 Verfahren zur Herstellung von neuen 4-Aza-benzimidazolderivaten und ihren Salzen AT315831B (de)

Priority Applications (19)

Application Number Priority Date Filing Date Title
BE788065D BE788065A (fr) 1971-08-26 Nouvelles aza-benzimidazoles et procede pour leur preparation
AT748871A AT315831B (de) 1971-08-26 1971-08-26 Verfahren zur Herstellung von neuen 4-Aza-benzimidazolderivaten und ihren Salzen
DD164684A DD99580A5 (ru) 1971-08-26 1972-07-26
YU2041/72A YU34897B (en) 1971-08-26 1972-08-09 Process for preparing 4-aza-benzimidazoles
IL40080A IL40080A (en) 1971-08-26 1972-08-09 4-aza-benzimidazoles,their production and pharmaceutical compositions containing them
CH1201872A CH592660A5 (ru) 1971-08-26 1972-08-14
SU1821216A SU557758A3 (ru) 1971-08-26 1972-08-18 Способ получени 4-азабензимидазолов или их солей
ES405982A ES405982A1 (es) 1971-08-26 1972-08-19 Procedimiento para la preparacion de 4-aza-bencimidazoles.
NL7211407A NL7211407A (ru) 1971-08-26 1972-08-21
FR7229915A FR2150820B1 (ru) 1971-08-26 1972-08-22
DE2241575A DE2241575A1 (de) 1971-08-26 1972-08-24 Neue aza-benzimidazole und verfahren zu deren herstellung
GB3940272A GB1397645A (en) 1971-08-26 1972-08-24 Aza-benzimidazoles
ZA725868A ZA725868B (en) 1971-08-26 1972-08-25 New aza-benzimidazoles and methods for the production thereof
BR5845/72A BR7205845A (pt) 1971-08-26 1972-08-25 Processo de preparacao de novos aza-benzimidazois
HUDE789A HU166382B (ru) 1971-08-26 1972-08-25
AU45981/72A AU461671B2 (en) 1971-08-26 1972-08-25 New aza-benzimidazoles and method of producing same
CA150,204A CA979907A (en) 1971-08-26 1972-08-25 Process for producing azabenzimidazoles
JP47085203A JPS4832898A (ru) 1971-08-26 1972-08-25
AR243765A AR199879A1 (es) 1971-08-26 1972-08-28 Procedimiento para la elaboracion de 4-aza-benzimidazoles

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT748871A AT315831B (de) 1971-08-26 1971-08-26 Verfahren zur Herstellung von neuen 4-Aza-benzimidazolderivaten und ihren Salzen

Publications (1)

Publication Number Publication Date
AT315831B true AT315831B (de) 1974-06-10

Family

ID=3596529

Family Applications (1)

Application Number Title Priority Date Filing Date
AT748871A AT315831B (de) 1971-08-26 1971-08-26 Verfahren zur Herstellung von neuen 4-Aza-benzimidazolderivaten und ihren Salzen

Country Status (19)

Country Link
JP (1) JPS4832898A (ru)
AR (1) AR199879A1 (ru)
AT (1) AT315831B (ru)
AU (1) AU461671B2 (ru)
BE (1) BE788065A (ru)
BR (1) BR7205845A (ru)
CA (1) CA979907A (ru)
CH (1) CH592660A5 (ru)
DD (1) DD99580A5 (ru)
DE (1) DE2241575A1 (ru)
ES (1) ES405982A1 (ru)
FR (1) FR2150820B1 (ru)
GB (1) GB1397645A (ru)
HU (1) HU166382B (ru)
IL (1) IL40080A (ru)
NL (1) NL7211407A (ru)
SU (1) SU557758A3 (ru)
YU (1) YU34897B (ru)
ZA (1) ZA725868B (ru)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0151824A2 (en) * 1984-01-09 1985-08-21 Janssen Pharmaceutica N.V. N-(4-piperidinyl) bicyclic condensed 2-imidazolamine derivatives

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1140119A (en) * 1978-04-03 1983-01-25 Joseph Torremans N-heterocyclyl-4-piperidinamines
US4772600A (en) * 1986-06-09 1988-09-20 A. H. Robins Company, Inc. Fused imidazoheterocyclic compounds and pharmaceutical compositions
JP2679745B2 (ja) * 1989-06-29 1997-11-19 明治製菓株式会社 アゾール誘導体及びそれらを有効成分とする抗潰瘍剤
US5200407A (en) * 1989-06-29 1993-04-06 Meiji Seika Kaburhiki Kaisha Azole derivatives and anti-ulcerative composition containing same
US6093728A (en) 1997-09-26 2000-07-25 Asta Medica Aktiengesellschaft Methods of modulating serine/threonine protein kinase function with azabenzimidazole-based compounds
US8227603B2 (en) 2006-08-01 2012-07-24 Cytokinetics, Inc. Modulating skeletal muscle
EP2995619B1 (en) 2006-08-02 2019-09-25 Cytokinetics, Inc. Certain chemical entities comprising imidazopyrimidines, compositions and methods
US8299248B2 (en) 2006-08-02 2012-10-30 Cytokinetics, Incorporated Certain 1H-imidazo[4,5-b]pyrazin-2(3H)-ones and 1H-imidazo[4,5-b]pyrazin-2-ols and methods for their use
US7851484B2 (en) * 2007-03-30 2010-12-14 Cytokinetics, Inc. Certain chemical entities, compositions, and methods
BR112013028895A2 (pt) 2011-05-10 2016-08-09 Bayer Ip Gmbh (tio)carbonilamidinas bicíclicas
KR101951220B1 (ko) 2011-07-13 2019-02-22 싸이토키네틱스, 인코포레이티드 조합 als 치료법
EP2733141B1 (en) * 2011-07-15 2019-01-09 Shionogi & Co., Ltd. Azabenzimidazole derivative having ampk-activating activity

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0151824A2 (en) * 1984-01-09 1985-08-21 Janssen Pharmaceutica N.V. N-(4-piperidinyl) bicyclic condensed 2-imidazolamine derivatives
EP0151824A3 (en) * 1984-01-09 1985-10-09 Janssen Pharmaceutica N.V. N-(4-piperidinyl) bicyclic condesed 2-imidazolamine derivatives

Also Published As

Publication number Publication date
FR2150820B1 (ru) 1975-10-17
HU166382B (ru) 1975-03-28
NL7211407A (ru) 1973-02-28
ES405982A1 (es) 1975-09-16
DD99580A5 (ru) 1973-08-12
SU557758A3 (ru) 1977-05-05
BR7205845A (pt) 1976-05-04
AU461671B2 (en) 1975-06-05
ZA725868B (en) 1973-05-30
FR2150820A1 (ru) 1973-04-13
GB1397645A (en) 1975-06-11
CH592660A5 (ru) 1977-10-31
IL40080A (en) 1975-12-31
BE788065A (fr) 1973-02-26
AU4598172A (en) 1974-02-28
YU204172A (en) 1979-10-31
YU34897B (en) 1980-04-30
BR7205845D0 (pt) 1973-07-03
IL40080A0 (en) 1972-10-29
DE2241575A1 (de) 1973-03-08
AR199879A1 (es) 1974-10-08
CA979907A (en) 1975-12-16
JPS4832898A (ru) 1973-05-02

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Legal Events

Date Code Title Description
ELJ Ceased due to non-payment of the annual fee