AT291283B - Verfahren zur Herstellung von neuen Guanylhydrazonen und ihren Salzen - Google Patents

Verfahren zur Herstellung von neuen Guanylhydrazonen und ihren Salzen

Info

Publication number
AT291283B
AT291283B AT330569A AT330569A AT291283B AT 291283 B AT291283 B AT 291283B AT 330569 A AT330569 A AT 330569A AT 330569 A AT330569 A AT 330569A AT 291283 B AT291283 B AT 291283B
Authority
AT
Austria
Prior art keywords
guanylhydrazones
salts
preparation
new
new guanylhydrazones
Prior art date
Application number
AT330569A
Other languages
English (en)
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH499868A external-priority patent/CH495960A/de
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Application granted granted Critical
Publication of AT291283B publication Critical patent/AT291283B/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C281/00Derivatives of carbonic acid containing functional groups covered by groups C07C269/00 - C07C279/00 in which at least one nitrogen atom of these functional groups is further bound to another nitrogen atom not being part of a nitro or nitroso group
    • C07C281/16Compounds containing any of the groups, e.g. aminoguanidine
    • C07C281/18Compounds containing any of the groups, e.g. aminoguanidine the other nitrogen atom being further doubly-bound to a carbon atom, e.g. guanylhydrazones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C335/00Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C335/04Derivatives of thiourea
    • C07C335/16Derivatives of thiourea having nitrogen atoms of thiourea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C335/20Derivatives of thiourea having nitrogen atoms of thiourea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/28Radicals substituted by nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT330569A 1968-04-04 1969-04-03 Verfahren zur Herstellung von neuen Guanylhydrazonen und ihren Salzen AT291283B (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH499868A CH495960A (de) 1968-04-04 1968-04-04 Verfahren zur Herstellung von neuen Guanylhydrazonen
CH268269 1969-02-21

Publications (1)

Publication Number Publication Date
AT291283B true AT291283B (de) 1971-07-12

Family

ID=25691134

Family Applications (2)

Application Number Title Priority Date Filing Date
AT343970A AT297731B (de) 1968-04-04 1969-04-03 Verfahren zur Herstellung von neuen Guanylhydrazonen und ihren Salzen
AT330569A AT291283B (de) 1968-04-04 1969-04-03 Verfahren zur Herstellung von neuen Guanylhydrazonen und ihren Salzen

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT343970A AT297731B (de) 1968-04-04 1969-04-03 Verfahren zur Herstellung von neuen Guanylhydrazonen und ihren Salzen

Country Status (9)

Country Link
US (1) US3673241A (de)
AT (2) AT297731B (de)
BE (1) BE731015A (de)
DE (1) DE1914999A1 (de)
FR (1) FR2007382B1 (de)
GB (1) GB1241130A (de)
IE (1) IE33021B1 (de)
NL (1) NL6905258A (de)
SE (1) SE343574B (de)

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GB1311432A (en) * 1971-01-07 1973-03-28 Ici Ltd Guanidine derivatives their preparation and antiviral compositions containing them
US3917678A (en) * 1972-01-25 1975-11-04 Squibb & Sons Inc Organic acid salts of 1-{8 0-{8 (3-dimethylaminopropyl)thio{9 phenyl{9 -3-methylurea
US5238941A (en) * 1988-03-25 1993-08-24 Ciba-Geigy Corporation Arylhydrazones and pharmaceutical compositions thereof
US4971986A (en) * 1988-03-25 1990-11-20 Ciba-Geigy Corporation Arylhydrazones useful as SAMDC inhibitors
WO2001017953A1 (en) 1999-09-08 2001-03-15 Guilford Pharmaceuticals Inc. Non-peptidic cyclophilin binding compounds and their use
WO2002059080A2 (en) 2001-01-25 2002-08-01 Guilford Pharmaceuticals Inc. Trisubstituted carbocyclic cyclophilin binding compounds and their use
SI1757606T1 (sl) * 2001-02-24 2009-10-31 Boehringer Ingelheim Pharma Ksantinski derivati za uporabo kot zdravila kot tudi postopek za njihovo pripravo
US7407955B2 (en) 2002-08-21 2008-08-05 Boehringer Ingelheim Pharma Gmbh & Co., Kg 8-[3-amino-piperidin-1-yl]-xanthines, the preparation thereof and their use as pharmaceutical compositions
US7501426B2 (en) * 2004-02-18 2009-03-10 Boehringer Ingelheim International Gmbh 8-[3-amino-piperidin-1-yl]-xanthines, their preparation and their use as pharmaceutical compositions
DE102004054054A1 (de) * 2004-11-05 2006-05-11 Boehringer Ingelheim Pharma Gmbh & Co. Kg Verfahren zur Herstellung chiraler 8-(3-Amino-piperidin-1-yl)-xanthine
DE102005035891A1 (de) * 2005-07-30 2007-02-08 Boehringer Ingelheim Pharma Gmbh & Co. Kg 8-(3-Amino-piperidin-1-yl)-xanthine, deren Herstellung und deren Verwendung als Arzneimittel
KR101452915B1 (ko) 2006-05-04 2014-10-21 베링거 인겔하임 인터내셔날 게엠베하 다형태
EP1852108A1 (de) * 2006-05-04 2007-11-07 Boehringer Ingelheim Pharma GmbH & Co.KG Zusammensetzungen von DPP-IV-Inhibitoren
PE20080251A1 (es) 2006-05-04 2008-04-25 Boehringer Ingelheim Int Usos de inhibidores de dpp iv
WO2008156573A1 (en) * 2007-06-12 2008-12-24 Provid Pharmaceuticals, Inc. Kinase inhibitors, compositions thereof, and methods of use therewith
NZ600126A (en) * 2007-08-17 2013-12-20 Boehringer Ingelheim Int Purine derivatives for use in the treatment of fap-related diseases
PE20140960A1 (es) 2008-04-03 2014-08-15 Boehringer Ingelheim Int Formulaciones que comprenden un inhibidor de dpp4
PE20100156A1 (es) * 2008-06-03 2010-02-23 Boehringer Ingelheim Int Tratamiento de nafld
KR20190016601A (ko) 2008-08-06 2019-02-18 베링거 인겔하임 인터내셔날 게엠베하 메트포르민 요법이 부적합한 환자에서의 당뇨병 치료
UY32030A (es) 2008-08-06 2010-03-26 Boehringer Ingelheim Int "tratamiento para diabetes en pacientes inapropiados para terapia con metformina"
WO2010018217A2 (en) * 2008-08-15 2010-02-18 Boehringer Ingelheim International Gmbh Organic compounds for wound healing
MX2011002558A (es) 2008-09-10 2011-04-26 Boehringer Ingelheim Int Terapia de combinacion para el tratamiento de diabetes y estados relacionados.
US20200155558A1 (en) 2018-11-20 2020-05-21 Boehringer Ingelheim International Gmbh Treatment for diabetes in patients with insufficient glycemic control despite therapy with an oral antidiabetic drug
AU2009331471B2 (en) 2008-12-23 2015-09-03 Boehringer Ingelheim International Gmbh Salt forms of organic compound
AR074990A1 (es) 2009-01-07 2011-03-02 Boehringer Ingelheim Int Tratamiento de diabetes en pacientes con un control glucemico inadecuado a pesar de la terapia con metformina
KR20120107080A (ko) 2009-11-27 2012-09-28 베링거 인겔하임 인터내셔날 게엠베하 리나글립틴과 같은 dpp-iv 억제제를 사용한 유전자형 검사된 당뇨병 환자의 치료
KR101927068B1 (ko) 2010-05-05 2018-12-10 베링거 인겔하임 인터내셔날 게엠베하 체중 감소 치료에 후속하는 dpp-4 억제제에 의한 순차적 병용 요법
KR20220025926A (ko) 2010-06-24 2022-03-03 베링거 인겔하임 인터내셔날 게엠베하 당뇨병 요법
AR083878A1 (es) 2010-11-15 2013-03-27 Boehringer Ingelheim Int Terapia antidiabetica vasoprotectora y cardioprotectora, linagliptina, metodo de tratamiento
CN103781788B (zh) 2011-07-15 2016-08-17 勃林格殷格翰国际有限公司 经取代的喹唑啉、其制备及其在药物组合物中的用途
US9555001B2 (en) 2012-03-07 2017-01-31 Boehringer Ingelheim International Gmbh Pharmaceutical composition and uses thereof
WO2013171166A1 (en) 2012-05-14 2013-11-21 Boehringer Ingelheim International Gmbh A xanthine derivative as dpp-4 inhibitor for use in the treatment of sirs and/or sepsis
JP6224084B2 (ja) 2012-05-14 2017-11-01 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 糸球体上皮細胞関連障害及び/又はネフローゼ症候群の治療に用いるdpp−4阻害薬としてのキサンチン誘導体
WO2013174767A1 (en) 2012-05-24 2013-11-28 Boehringer Ingelheim International Gmbh A xanthine derivative as dpp -4 inhibitor for use in modifying food intake and regulating food preference
CN102924339B (zh) * 2012-11-23 2014-06-04 温州澳珀化工有限公司 一种制备米托胍腙的方法
JP6615109B2 (ja) 2014-02-28 2019-12-04 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング Dpp−4阻害薬の医学的使用
EP3156394B1 (de) * 2014-06-10 2019-04-17 Mitsubishi Gas Chemical Company, Inc. Alkylidenaminoganidin und salz davon, modifikatorzusammensetzung, modifizierter kautschuk für reifen, kautschukzusammensetzung für reifen und reifen
MX390363B (es) 2016-06-10 2025-03-20 Boehringer Ingelheim Int Combinacion de linagliptina y metformina
FR3112428A1 (fr) 2020-07-13 2022-01-14 Semco Smartech France Procédé de formation de contacts passivés pour cellules solaires IBC

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2584784A (en) * 1949-05-21 1952-02-05 Du Pont Salts of 1-salicylalaminoguanidine
FR1013816A (fr) * 1949-05-24 1952-08-05 Wander Ag Dr A Procédé pour la préparation de p-uréidobenzalthio-semicarbazones substituées
CH383948A (de) * 1959-07-22 1964-11-15 Ciba Geigy Verfahren zur Herstellung neuer Hydrazone
FR1332543A (fr) * 1962-01-09 1963-07-19 Ciba Geigy Nouvelles hydrazones et leur procédé de préparation

Also Published As

Publication number Publication date
GB1241130A (en) 1971-07-28
IE33021B1 (en) 1974-02-20
FR2007382A1 (de) 1970-01-09
BE731015A (de) 1969-10-03
US3673241A (en) 1972-06-27
DE1914999A1 (de) 1969-11-06
AT297731B (de) 1972-04-10
NL6905258A (de) 1969-10-07
IE33021L (en) 1969-10-04
FR2007382B1 (de) 1974-02-01
SE343574B (de) 1972-03-13

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