AT288356B - Process for the preparation of new 1- (3 ', 5'-dihydroxy- or -acyloxy-phenyl) -2-alkylaminoethanols and their physiologically acceptable acid addition salts - Google Patents

Process for the preparation of new 1- (3 ', 5'-dihydroxy- or -acyloxy-phenyl) -2-alkylaminoethanols and their physiologically acceptable acid addition salts

Info

Publication number
AT288356B
AT288356B AT941969A AT941969A AT288356B AT 288356 B AT288356 B AT 288356B AT 941969 A AT941969 A AT 941969A AT 941969 A AT941969 A AT 941969A AT 288356 B AT288356 B AT 288356B
Authority
AT
Austria
Prior art keywords
alkylaminoethanols
acyloxy
dihydroxy
phenyl
preparation
Prior art date
Application number
AT941969A
Other languages
German (de)
Inventor
Kjell Ingvar Leopold Wetterlin
Leif Aake Svensson
Original Assignee
Draco Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Draco Ab filed Critical Draco Ab
Application granted granted Critical
Publication of AT288356B publication Critical patent/AT288356B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/004—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reaction with organometalhalides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C07C45/48—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation involving decarboxylation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/63—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/673—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
AT941969A 1966-10-19 1967-10-10 Process for the preparation of new 1- (3 ', 5'-dihydroxy- or -acyloxy-phenyl) -2-alkylaminoethanols and their physiologically acceptable acid addition salts AT288356B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE14182/66A SE335359B (en) 1966-10-19 1966-10-19

Publications (1)

Publication Number Publication Date
AT288356B true AT288356B (en) 1971-03-10

Family

ID=20298669

Family Applications (4)

Application Number Title Priority Date Filing Date
AT941969A AT288356B (en) 1966-10-19 1967-10-10 Process for the preparation of new 1- (3 ', 5'-dihydroxy- or -acyloxy-phenyl) -2-alkylaminoethanols and their physiologically acceptable acid addition salts
AT09421/69A AT287679B (en) 1966-10-19 1967-10-10 PROCESS FOR THE PRODUCTION OF NEW 1- (3 ', 5'-DIHYDROXY-OR ACYLOXYPHENYL) -2-CYCLOBUTYLAMINOETHANOLS AND THEIR PHYSIOLOGICALLY COMPATIBLE ACID ADDITIONAL SALTS
AT09420/69A AT287678B (en) 1966-10-19 1967-10-10 PROCESS FOR THE PRODUCTION OF NEW 1- (3 ', 5'-DIHYDROXY-OR ACYLOXY-PHENYL) -2-ALKYLAMINO-AETHANOLS AND THEIR PHYSIOLOGICALLY COMPATIBLE ACID ADDITIONAL SALTS
AT915967A AT286964B (en) 1966-10-19 1967-10-10 Process for the preparation of new 1- (3 ', 5'-dihydroxy- or -acyloxy-phenyl) -2-alkylaminoethanols and their physiologically acceptable acid addition salts

Family Applications After (3)

Application Number Title Priority Date Filing Date
AT09421/69A AT287679B (en) 1966-10-19 1967-10-10 PROCESS FOR THE PRODUCTION OF NEW 1- (3 ', 5'-DIHYDROXY-OR ACYLOXYPHENYL) -2-CYCLOBUTYLAMINOETHANOLS AND THEIR PHYSIOLOGICALLY COMPATIBLE ACID ADDITIONAL SALTS
AT09420/69A AT287678B (en) 1966-10-19 1967-10-10 PROCESS FOR THE PRODUCTION OF NEW 1- (3 ', 5'-DIHYDROXY-OR ACYLOXY-PHENYL) -2-ALKYLAMINO-AETHANOLS AND THEIR PHYSIOLOGICALLY COMPATIBLE ACID ADDITIONAL SALTS
AT915967A AT286964B (en) 1966-10-19 1967-10-10 Process for the preparation of new 1- (3 ', 5'-dihydroxy- or -acyloxy-phenyl) -2-alkylaminoethanols and their physiologically acceptable acid addition salts

Country Status (13)

Country Link
AT (4) AT288356B (en)
BE (1) BE704932A (en)
CH (1) CH510625A (en)
DE (2) DE1643296C3 (en)
DK (2) DK128491B (en)
ES (5) ES346131A1 (en)
FI (1) FI50786C (en)
FR (1) FR8011M (en)
GB (1) GB1199630A (en)
IT (1) IT8048168A0 (en)
NL (2) NL151693B (en)
NO (1) NO120686B (en)
SE (1) SE335359B (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4138581A (en) 1969-04-01 1979-02-06 Sterling Drugs Inc. 3(Hydroxy or hydroxymethyl)-4(hydroxy)-α-(aminomethyl)benzyl alcohols
DE3163871D1 (en) 1980-07-09 1984-07-05 Draco Ab 1-(dihydroxyphenyl)-2-amino-ethanol derivatives; preparation, compositions and intermediates
EP0046144B1 (en) * 1980-07-09 1984-04-11 Aktiebolaget Draco Therapeutically active derivatives of phenylethanol amines
US4853381A (en) * 1984-04-17 1989-08-01 Glaxo Group Limited Ethanolamine compounds
US4581225A (en) * 1984-04-25 1986-04-08 Eli Lilly And Company Sustained release intranasal formulation and method of use thereof
EP0213108A3 (en) * 1985-06-26 1987-07-15 Kurt Dr. Burghart Pharmaceutical preparation containing an antihypotonic as the active agent
WO2013081565A1 (en) 2011-11-21 2013-06-06 Mahmut Bilgic Pharmaceutical compositions comprising roflumilast and terbutaline
WO2014108449A1 (en) 2013-01-08 2014-07-17 Atrogi Ab A screening method, a kit, a method of treatment and a compound for use in a method of treatment
WO2018182546A1 (en) 2017-03-27 2018-10-04 İlko Ilaç Sanayi Ve Ticaret Anonim Şirketi Stabilized pharmaceutical syrup composition comprising terbutaline sulphate and ambroxol hydrochloride
GB201714734D0 (en) 2017-09-13 2017-10-25 Atrogi Ab New compounds and uses
GB201714745D0 (en) 2017-09-13 2017-10-25 Atrogi Ab New compounds and uses
GB201714740D0 (en) 2017-09-13 2017-10-25 Atrogi Ab New compounds and uses
GB201714736D0 (en) 2017-09-13 2017-10-25 Atrogi Ab New compounds and uses
CN110057932B (en) * 2019-04-22 2022-03-15 上海旭东海普药业有限公司 Method for analyzing terbutaline sulfate related substances by high performance liquid chromatography
CN111440078A (en) * 2020-04-26 2020-07-24 梯尔希（南京）药物研发有限公司 Preparation method of terbutaline derivative
CN113264839B (en) * 2021-04-27 2022-08-30 苏州弘森药业股份有限公司 Method for preparing levo-terbutaline by using chiral prosthetic group
GB202205895D0 (en) 2022-04-22 2022-06-08 Atrogi Ab New medical uses

Also Published As

Publication number Publication date
DE1643296A1 (en) 1971-09-30
FR8011M (en) 1970-07-27
DE1643296C3 (en) 1974-06-12
GB1199630A (en) 1970-07-22
DE1643296B2 (en) 1973-10-25
DE1793759B2 (en) 1978-05-11
CH510625A (en) 1971-07-31
SE335359B (en) 1971-05-24
DK468876A (en) 1976-10-18
ES361433A1 (en) 1970-11-01
FI50786C (en) 1976-07-12
ES361432A1 (en) 1970-11-01
NL7513854A (en) 1976-03-31
DE1793759A1 (en) 1973-08-16
NL151693B (en) 1976-12-15
ES361431A1 (en) 1970-11-01
NL6714191A (en) 1968-04-22
DE1793759C3 (en) 1979-01-11
AT287678B (en) 1971-02-10
DK128491B (en) 1974-05-13
BE704932A (en) 1968-02-15
NO120686B (en) 1970-11-23
ES361429A1 (en) 1970-11-01
AT287679B (en) 1971-02-10
FI50786B (en) 1976-03-31
IT8048168A0 (en) 1980-03-14
AT286964B (en) 1971-01-11
ES346131A1 (en) 1969-05-16

Similar Documents

Publication Publication Date Title
AT291968B (en) Process for the preparation of new 1- (4'-acylaminophenoxy) -2-hydroxy-3-aminopropanes and their acid addition salts
AT288358B (en) Process for the preparation of new 1- (3 ', 4'-dihydroxyphenyl) -2-aminoalkanols and their acid addition salts
AT277973B (en) Process for the preparation of new amino-dihalophenylethylamines and of their acid addition salts
AT278806B (en) Process for the preparation of new azaspiroalkanedione compounds and their pharmaceutically acceptable acid addition salts
AT288356B (en) Process for the preparation of new 1- (3 ', 5'-dihydroxy- or -acyloxy-phenyl) -2-alkylaminoethanols and their physiologically acceptable acid addition salts
AT290502B (en) Process for the preparation of new 1- (4'-acylaminophenoxy) -2-hydroxy-3-aminopropanes and their acid addition salts
AT273076B (en) Process for the preparation of new phenoxypropylamines and their acid addition salts
AT277209B (en) Process for the preparation of new 3,3-diphenylpropene- (2) -ylamines and their acid addition salts
AT276346B (en) Process for the preparation of new diarylcyclopropylmethylamines, and their acid addition and quaternary salts
AT284087B (en) Process for the preparation of new, mixed substituted 1-phenoxy-3-alkylaminopropanolen- (2) and their acid addition salts
CH512428A (en) Process for the preparation of new 1- (3 ', 5'-dihydroxy- or -acyloxy-phenyl) -2-aminoethanols and their physiologically acceptable acid addition salts
AT271423B (en) Process for the preparation of new bicyclo [2,2,2] octyl-methylamines and their acid addition salts
AT289827B (en) Process for the preparation of new N-anilinophenyl-N'-alkylureas and their salts
AT300761B (en) Process for the preparation of the new 1- (3 ', 5'-dihydroxy- or 3', 5'-diacyloxyphenyl) -2-cyclopentylaminobutanol and its acid addition salts
AT303700B (en) Process for the preparation of new 1- [1 ', 4'-methano- or 1', 4'-ethano-1 ', 2', 3 ', 4'-tetrahydronaphthyloxy] -2-hydroxy-3-aminopropanes and their acid addition salts
AT280987B (en) Process for the preparation of new bicyclo [2.2.2] oct-2-en-1-ylmethylamines and their acid addition salts
AT273927B (en) Process for the preparation of new 1-substituted 1-phenyl-2-aminoethanols and their acid addition salts
AT273932B (en) Process for the preparation of new 1- (3'-hydroxyphenyl) -2-acylaminoalkanolen- (1) and their O <1> -mono- or O, O-diacyl derivatives
AT280294B (en) Process for the preparation of new 1,3-dihydro-5-phenyl-7-trifluoromethoxy-2H-1,4-benzodiazepin-2-ones and of their non-toxic acid addition salts
AT259568B (en) Process for the preparation of new 1,2,8,9-tetraazaphenalenes and their physiologically acceptable acid addition salts
AT276417B (en) Process for the preparation of new 3,1-benzothiazine derivatives and their salts
AT286264B (en) PROCESS FOR THE PREPARATION OF NEW 1-PHENOXY-2-AMINO ALKANS AND THEIR ACID ADDITION SALTS
AT269155B (en) Process for the preparation of new fluoreno- [1,9-ef] -1,4-diazepine-1-oxides and their acid addition salts
AT266855B (en) Process for the preparation of new 2,6-dihalo-phenylalkylaminoguanidines and their acid addition salts
AT316517B (en) Process for the preparation of new substituted 1- (4'-amino-3'-halophenyl) -4-aminobutane (1) -ols and their acid addition salts

Legal Events

Date Code Title Description
ELA Expired due to lapse of time