AT287679B - PROCESS FOR THE PRODUCTION OF NEW 1- (3 ', 5'-DIHYDROXY-OR ACYLOXYPHENYL) -2-CYCLOBUTYLAMINOETHANOLS AND THEIR PHYSIOLOGICALLY COMPATIBLE ACID ADDITIONAL SALTS - Google Patents

PROCESS FOR THE PRODUCTION OF NEW 1- (3 ', 5'-DIHYDROXY-OR ACYLOXYPHENYL) -2-CYCLOBUTYLAMINOETHANOLS AND THEIR PHYSIOLOGICALLY COMPATIBLE ACID ADDITIONAL SALTS

Info

Publication number
AT287679B
AT287679B AT09421/69A AT942167A AT287679B AT 287679 B AT287679 B AT 287679B AT 09421/69 A AT09421/69 A AT 09421/69A AT 942167 A AT942167 A AT 942167A AT 287679 B AT287679 B AT 287679B
Authority
AT
Austria
Prior art keywords
cyclobutylaminoethanols
acyloxyphenyl
dihydroxy
new
production
Prior art date
Application number
AT09421/69A
Other languages
German (de)
Inventor
K Wetterlin
L Svensson
Original Assignee
Draco Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Draco Ab filed Critical Draco Ab
Application granted granted Critical
Publication of AT287679B publication Critical patent/AT287679B/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/004Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reaction with organometalhalides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C07C45/48Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation involving decarboxylation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/63Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/673Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT09421/69A 1966-10-19 1967-10-10 PROCESS FOR THE PRODUCTION OF NEW 1- (3 ', 5'-DIHYDROXY-OR ACYLOXYPHENYL) -2-CYCLOBUTYLAMINOETHANOLS AND THEIR PHYSIOLOGICALLY COMPATIBLE ACID ADDITIONAL SALTS AT287679B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE14182/66A SE335359B (en) 1966-10-19 1966-10-19

Publications (1)

Publication Number Publication Date
AT287679B true AT287679B (en) 1971-02-10

Family

ID=20298669

Family Applications (4)

Application Number Title Priority Date Filing Date
AT09420/69A AT287678B (en) 1966-10-19 1967-10-10 PROCESS FOR THE PRODUCTION OF NEW 1- (3 ', 5'-DIHYDROXY-OR ACYLOXY-PHENYL) -2-ALKYLAMINO-AETHANOLS AND THEIR PHYSIOLOGICALLY COMPATIBLE ACID ADDITIONAL SALTS
AT915967A AT286964B (en) 1966-10-19 1967-10-10 Process for the preparation of new 1- (3 ', 5'-dihydroxy- or -acyloxy-phenyl) -2-alkylaminoethanols and their physiologically acceptable acid addition salts
AT941969A AT288356B (en) 1966-10-19 1967-10-10 Process for the preparation of new 1- (3 ', 5'-dihydroxy- or -acyloxy-phenyl) -2-alkylaminoethanols and their physiologically acceptable acid addition salts
AT09421/69A AT287679B (en) 1966-10-19 1967-10-10 PROCESS FOR THE PRODUCTION OF NEW 1- (3 ', 5'-DIHYDROXY-OR ACYLOXYPHENYL) -2-CYCLOBUTYLAMINOETHANOLS AND THEIR PHYSIOLOGICALLY COMPATIBLE ACID ADDITIONAL SALTS

Family Applications Before (3)

Application Number Title Priority Date Filing Date
AT09420/69A AT287678B (en) 1966-10-19 1967-10-10 PROCESS FOR THE PRODUCTION OF NEW 1- (3 ', 5'-DIHYDROXY-OR ACYLOXY-PHENYL) -2-ALKYLAMINO-AETHANOLS AND THEIR PHYSIOLOGICALLY COMPATIBLE ACID ADDITIONAL SALTS
AT915967A AT286964B (en) 1966-10-19 1967-10-10 Process for the preparation of new 1- (3 ', 5'-dihydroxy- or -acyloxy-phenyl) -2-alkylaminoethanols and their physiologically acceptable acid addition salts
AT941969A AT288356B (en) 1966-10-19 1967-10-10 Process for the preparation of new 1- (3 ', 5'-dihydroxy- or -acyloxy-phenyl) -2-alkylaminoethanols and their physiologically acceptable acid addition salts

Country Status (13)

Country Link
AT (4) AT287678B (en)
BE (1) BE704932A (en)
CH (1) CH510625A (en)
DE (2) DE1643296C3 (en)
DK (2) DK128491B (en)
ES (5) ES346131A1 (en)
FI (1) FI50786C (en)
FR (1) FR8011M (en)
GB (1) GB1199630A (en)
IT (1) IT8048168A0 (en)
NL (2) NL151693B (en)
NO (1) NO120686B (en)
SE (1) SE335359B (en)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4138581A (en) 1969-04-01 1979-02-06 Sterling Drugs Inc. 3(Hydroxy or hydroxymethyl)-4(hydroxy)-α-(aminomethyl)benzyl alcohols
CY1271A (en) * 1980-07-09 1985-03-08 Draco Ab Therapeutically active derivatives of phenylethanol amines
EP0043807B1 (en) 1980-07-09 1984-05-30 Aktiebolaget Draco 1-(dihydroxyphenyl)-2-amino-ethanol derivatives; preparation, compositions and intermediates
US4853381A (en) * 1984-04-17 1989-08-01 Glaxo Group Limited Ethanolamine compounds
US4581225A (en) * 1984-04-25 1986-04-08 Eli Lilly And Company Sustained release intranasal formulation and method of use thereof
EP0213108A3 (en) * 1985-06-26 1987-07-15 Kurt Dr. Burghart Pharmaceutical preparation containing an antihypotonic as the active agent
WO2013081565A1 (en) 2011-11-21 2013-06-06 Mahmut Bilgic Pharmaceutical compositions comprising roflumilast and terbutaline
WO2014108449A1 (en) 2013-01-08 2014-07-17 Atrogi Ab A screening method, a kit, a method of treatment and a compound for use in a method of treatment
WO2018182546A1 (en) 2017-03-27 2018-10-04 İlko Ilaç Sanayi Ve Ticaret Anonim Şirketi Stabilized pharmaceutical syrup composition comprising terbutaline sulphate and ambroxol hydrochloride
GB201714740D0 (en) 2017-09-13 2017-10-25 Atrogi Ab New compounds and uses
GB201714736D0 (en) 2017-09-13 2017-10-25 Atrogi Ab New compounds and uses
GB201714734D0 (en) 2017-09-13 2017-10-25 Atrogi Ab New compounds and uses
GB201714745D0 (en) 2017-09-13 2017-10-25 Atrogi Ab New compounds and uses
GB201903832D0 (en) 2019-03-20 2019-05-01 Atrogi Ab New compounds and methods
CN110057932B (en) * 2019-04-22 2022-03-15 上海旭东海普药业有限公司 Method for analyzing terbutaline sulfate related substances by high performance liquid chromatography
CN111440078A (en) * 2020-04-26 2020-07-24 梯尔希(南京)药物研发有限公司 Preparation method of terbutaline derivative
CN113264839B (en) * 2021-04-27 2022-08-30 苏州弘森药业股份有限公司 Method for preparing levo-terbutaline by using chiral prosthetic group
GB202205895D0 (en) 2022-04-22 2022-06-08 Atrogi Ab New medical uses
CN120583945A (en) 2023-01-20 2025-09-02 阿托基公司 Beta2-adrenergic receptor agonists for the treatment or prevention of muscle wasting
GB202302225D0 (en) 2023-02-16 2023-04-05 Atrogi Ab New medical uses
GB202303229D0 (en) 2023-03-06 2023-04-19 Atrogi Ab New medical uses
GB202403169D0 (en) 2024-03-05 2024-04-17 Atrogi Ab New medical uses

Also Published As

Publication number Publication date
FI50786C (en) 1976-07-12
ES361432A1 (en) 1970-11-01
DE1643296A1 (en) 1971-09-30
SE335359B (en) 1971-05-24
FI50786B (en) 1976-03-31
ES346131A1 (en) 1969-05-16
NL7513854A (en) 1976-03-31
AT287678B (en) 1971-02-10
AT288356B (en) 1971-03-10
DE1793759C3 (en) 1979-01-11
ES361433A1 (en) 1970-11-01
GB1199630A (en) 1970-07-22
DE1793759B2 (en) 1978-05-11
DK128491B (en) 1974-05-13
NL151693B (en) 1976-12-15
FR8011M (en) 1970-07-27
DE1793759A1 (en) 1973-08-16
ES361429A1 (en) 1970-11-01
ES361431A1 (en) 1970-11-01
IT8048168A0 (en) 1980-03-14
CH510625A (en) 1971-07-31
NO120686B (en) 1970-11-23
DK468876A (en) 1976-10-18
AT286964B (en) 1971-01-11
DE1643296C3 (en) 1974-06-12
BE704932A (en) 1968-02-15
DE1643296B2 (en) 1973-10-25
NL6714191A (en) 1968-04-22

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