AT250951B - Verfahren zur Herstellung von neuen Pyrrolo [1, 2-a]-indolderivaten - Google Patents
Verfahren zur Herstellung von neuen Pyrrolo [1, 2-a]-indolderivatenInfo
- Publication number
- AT250951B AT250951B AT457663A AT457663A AT250951B AT 250951 B AT250951 B AT 250951B AT 457663 A AT457663 A AT 457663A AT 457663 A AT457663 A AT 457663A AT 250951 B AT250951 B AT 250951B
- Authority
- AT
- Austria
- Prior art keywords
- preparation
- indole derivatives
- new pyrrolo
- pyrrolo
- new
- Prior art date
Links
- GOHIXUOTOMMONS-UHFFFAOYSA-N 1h-pyrrolo[1,2-a]indole Chemical class C1=CC=C2N3CC=CC3=CC2=C1 GOHIXUOTOMMONS-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Indole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US200649A US3206470A (en) | 1962-06-07 | 1962-06-07 | Novel pyrrolo[1, 2-alpha]indoles |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AT250951B true AT250951B (de) | 1966-12-12 |
Family
ID=22742594
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT457663A AT250951B (de) | 1962-06-07 | 1963-06-06 | Verfahren zur Herstellung von neuen Pyrrolo [1, 2-a]-indolderivaten |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US3206470A (OSRAM) |
| AT (1) | AT250951B (OSRAM) |
| BE (1) | BE633281A (OSRAM) |
| BR (1) | BR6349521D0 (OSRAM) |
| DE (1) | DE1445422A1 (OSRAM) |
| ES (1) | ES288785A1 (OSRAM) |
| GB (1) | GB1033253A (OSRAM) |
| NL (1) | NL293572A (OSRAM) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4089969A (en) * | 1976-07-14 | 1978-05-16 | Syntex (U.S.A.) Inc. | 5-Aroyl-1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic acid derivatives and process for the production thereof |
| US4097579A (en) * | 1977-03-31 | 1978-06-27 | Syntex (U.S.A.) Inc. | 5-(2-Pyrroyl)-1,2-dihydro-3H-pyrrolo 1,2-a!pyrrole-1-carboxylic acid derivatives and process for the production thereof |
| US4134894A (en) * | 1978-05-04 | 1979-01-16 | Warner-Lambert Company | Pyrrolo[1,2-a]indole compounds |
| US4778812A (en) * | 1987-06-12 | 1988-10-18 | American Home Products Corporation | 2,3-dihydro-9-methyl-1H-pyrrolo[1,2-a]indol-1-amines and derivatives thereof |
| US7125906B2 (en) | 2002-04-03 | 2006-10-24 | Astrazeneca Ab | Indole derivatives having anti-angiogenetic activity |
| BRPI0916812B8 (pt) | 2008-07-23 | 2022-10-18 | Arena Pharm Inc | Derivados do ácido 1,2,3,4-tetra-hidrociclopenta[b]indol-3-il)acético substituído úteis no tratamento de distúrbios autoimunes e inflamatórios, seu uso, composição farmacêutica que os compreende e processo de preparação |
| PT2342205T (pt) | 2008-08-27 | 2016-07-28 | Arena Pharm Inc | Derivados de ácido tricíclico substituído como agonistas de recetor s1p1 úteis no tratamento de distúrbios autoimunes e inflamatórios |
| ES2937386T3 (es) | 2010-01-27 | 2023-03-28 | Arena Pharm Inc | Procesos para la preparación de ácido (R)-2-(7-(4-ciclopentil-3-(trifluorometil)benciloxi)-1,2,3,4-tetrahidrociclopenta[b]indol-3-il)acético y sales del mismo |
| CN102884064B (zh) * | 2010-03-03 | 2016-01-13 | 艾尼纳制药公司 | 制备s1p1受体调节剂及其晶体形式的方法 |
| UA126268C2 (uk) | 2015-01-06 | 2022-09-14 | Арена Фармасьютікалз, Інк. | СПОСОБИ ЛІКУВАННЯ СТАНІВ, ПОВ'ЯЗАНИХ З РЕЦЕПТОРОМ S1P<sub>1 </sub> |
| MA42807A (fr) | 2015-06-22 | 2018-07-25 | Arena Pharm Inc | Sel l-arginine cristallin d'acide (r)-2-(7-(4-cyclopentyl-3-(trifluorométhyl)benzyloxy)-1,2,3,4-tétrahydrocyclo-penta[b]indol-3-yl)acétique (composé 1) pour une utilisation dans des troubles associés au récepteur de s1p1 |
| MA47504A (fr) | 2017-02-16 | 2019-12-25 | Arena Pharm Inc | Composés et méthodes de traitement de l'angiocholite biliaire primitive |
| AU2018222747A1 (en) | 2017-02-16 | 2019-09-05 | Arena Pharmaceuticals, Inc. | Compounds and methods for treatment of inflammatory bowel disease with extra-intestinal manifestations |
| KR102859841B1 (ko) | 2018-06-06 | 2025-09-12 | 아레나 파마슈티칼스, 인크. | S1p1 수용체와 관련된 병태의 치료 방법 |
| WO2020051378A1 (en) | 2018-09-06 | 2020-03-12 | Arena Pharmaceuticals, Inc. | Compounds useful in the treatment of autoimmune and inflammatory disorders |
| CN110878099B (zh) * | 2019-11-25 | 2021-11-30 | 五邑大学 | 一种吡咯[1,2,α]吲哚生物碱衍生物的制备方法 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2707187A (en) * | 1952-07-14 | 1955-04-26 | Upjohn Co | Chemical process |
-
0
- NL NL293572D patent/NL293572A/xx unknown
-
1962
- 1962-06-07 US US200649A patent/US3206470A/en not_active Expired - Lifetime
-
1963
- 1963-05-23 GB GB20589/63A patent/GB1033253A/en not_active Expired
- 1963-05-31 BR BR149521/63A patent/BR6349521D0/pt unknown
- 1963-06-05 BE BE633281A patent/BE633281A/fr unknown
- 1963-06-06 AT AT457663A patent/AT250951B/de active
- 1963-06-06 DE DE19631445422 patent/DE1445422A1/de active Pending
- 1963-06-06 ES ES288785A patent/ES288785A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| BR6349521D0 (pt) | 1973-07-03 |
| DE1445422A1 (de) | 1969-04-10 |
| US3206470A (en) | 1965-09-14 |
| BE633281A (fr) | 1963-12-05 |
| GB1033253A (en) | 1966-06-22 |
| NL293572A (OSRAM) | |
| ES288785A1 (es) | 1963-11-16 |
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