AR248047A1 - Procedimiento para la preparacion de una vacuna a base de virus del herpes bovina modificado tipo 1. - Google Patents
Procedimiento para la preparacion de una vacuna a base de virus del herpes bovina modificado tipo 1.Info
- Publication number
- AR248047A1 AR248047A1 AR92323900A AR32390092A AR248047A1 AR 248047 A1 AR248047 A1 AR 248047A1 AR 92323900 A AR92323900 A AR 92323900A AR 32390092 A AR32390092 A AR 32390092A AR 248047 A1 AR248047 A1 AR 248047A1
- Authority
- AR
- Argentina
- Prior art keywords
- bhv
- modified
- strain
- sequences
- amino acid
- Prior art date
Links
- 241000283690 Bos taurus Species 0.000 title abstract 2
- 241001529453 unidentified herpesvirus Species 0.000 title abstract 2
- 229960005486 vaccine Drugs 0.000 title abstract 2
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 2
- 241000700605 Viruses Species 0.000 abstract 2
- 150000001413 amino acids Chemical class 0.000 abstract 2
- 210000004027 cell Anatomy 0.000 abstract 2
- 238000012986 modification Methods 0.000 abstract 2
- 102000004169 proteins and genes Human genes 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 102000003886 Glycoproteins Human genes 0.000 abstract 1
- 108090000288 Glycoproteins Proteins 0.000 abstract 1
- 241001465754 Metazoa Species 0.000 abstract 1
- MTCFGRXMJLQNBG-UHFFFAOYSA-N Serine Natural products OCC(N)C(O)=O MTCFGRXMJLQNBG-UHFFFAOYSA-N 0.000 abstract 1
- 239000002671 adjuvant Substances 0.000 abstract 1
- 210000004102 animal cell Anatomy 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 210000002966 serum Anatomy 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2/00—Peptides of undefined number of amino acids; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16711—Varicellovirus, e.g. human herpesvirus 3, Varicella Zoster, pseudorabies
- C12N2710/16721—Viruses as such, e.g. new isolates, mutants or their genomic sequences
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16711—Varicellovirus, e.g. human herpesvirus 3, Varicella Zoster, pseudorabies
- C12N2710/16722—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biotechnology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Communicable Diseases (AREA)
- Biophysics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
PROCEDIMIENTO PARA LA PREPARACION DE UNA VACUNA QUE COMPRENDE UNA CEPA DE HERPESVIRUS BOVINO DEL SEROTIPO 1 (BHV-1), CUYA CEPA MUTANTE TIENE UNO O MAS SECUENCIAS DE AMINOACIDOS MODIFICADAS EN REGIONES NO ESENCIALES DE PROTEINAS ESENCIALES AL COMPARARSE CON UNA CEPA NORMAL DEL VIRUS DEL CAMPO BHV-1, LAS SECUENCIAS DE AMINOACIDOS MODIFICADAS QUE RESULTAN A PARTIR DE LAS MODIFICACIONES EN UNO O MAS PUNTOS DE LAS SECUENCIAS NORMALES DE ADN QUE CODIFICAN LAS PROTEINAS ESENCIALES, DONDE UN CEPA MODIFICADA DEL VIRUS BHV-1 SUBTIPO 3(BVH-1.3), EN DONDE LAS MODIFICACIONES EN LAS SECUENCIAS DE AMINOACIDO Y ADN QUE AFECTAN A LA GLICOPROTEINA GIV, ES REPLICADA EN CULTIVOS DE TEJIDO DE CELULAS ANIMALES COMO EN CELULAS PRIMARIAS O EN LINEAS CELULARES PERMANENTES EN CULTIVOS ESTACIONARIOS, DE RODILLOS O PORTADORES CON UN MEDIO DE REPLICACION QUE CONTIENE LA ADICION DE SUERO ANIMAL DE HASTA 30% POR VOLUMEN ENTRE 32 Y 39*C, SIENDO EL MEDIO QUE CONTIENE EL VIRUS SEPARADO DE TODOS LOS DETRITOS Y AISL ADO, EVENTUALMENTE INACTIVADO Y FORMULADO EN CONJUNTO CON UN ADYUVANTE.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4141400A DE4141400A1 (de) | 1991-12-16 | 1991-12-16 | Impfstoffe auf basis geaenderter boviner herpesviren typ 1 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR248047A1 true AR248047A1 (es) | 1995-05-31 |
Family
ID=6447143
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AR92323900A AR248047A1 (es) | 1991-12-16 | 1992-12-15 | Procedimiento para la preparacion de una vacuna a base de virus del herpes bovina modificado tipo 1. |
Country Status (13)
| Country | Link |
|---|---|
| EP (1) | EP0547446B1 (es) |
| JP (1) | JPH05276942A (es) |
| KR (1) | KR100265717B1 (es) |
| AR (1) | AR248047A1 (es) |
| AT (1) | ATE165620T1 (es) |
| AU (1) | AU660741B2 (es) |
| CA (1) | CA2085191C (es) |
| DE (2) | DE4141400A1 (es) |
| DK (1) | DK0547446T3 (es) |
| ES (1) | ES2116306T3 (es) |
| HU (2) | HU9203976D0 (es) |
| MX (1) | MX9206973A (es) |
| ZA (1) | ZA929719B (es) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6410033B1 (en) | 1987-07-27 | 2002-06-25 | Syntro Corporation | Recombinant infectious bovine rhinotracheitis virus |
| US5783195A (en) * | 1991-07-18 | 1998-07-21 | Syntro Corporation | Recombinant infectious bovine rhinotracheitis virus S-IBR-052 and uses thereof |
| NL9100989A (nl) * | 1991-06-07 | 1993-01-04 | Stichting Centr Diergeneeskund | Bovine herpesvirus type 1 deletiemutanten, daarop gebaseerde vaccins, diagnostische kits voor detectie van bovine herpesvirus type 1. |
| CA2136381A1 (en) * | 1993-11-23 | 1995-05-24 | Gunther Keil | Vector vaccines of bovine herpesvirus 1 |
| EP0663403A1 (en) * | 1993-11-23 | 1995-07-19 | Akzo Nobel N.V. | Vector vaccines of bovine herpesvirus I |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4992051A (en) * | 1987-11-03 | 1991-02-12 | Novagene, Inc. | Infectious bovine rhinotracheitis virus mutants, methods for the production of same and methods for the use of same |
| NL9100989A (nl) * | 1991-06-07 | 1993-01-04 | Stichting Centr Diergeneeskund | Bovine herpesvirus type 1 deletiemutanten, daarop gebaseerde vaccins, diagnostische kits voor detectie van bovine herpesvirus type 1. |
-
1991
- 1991-12-16 DE DE4141400A patent/DE4141400A1/de not_active Withdrawn
-
1992
- 1992-11-26 AU AU29688/92A patent/AU660741B2/en not_active Ceased
- 1992-12-03 MX MX9206973A patent/MX9206973A/es not_active IP Right Cessation
- 1992-12-03 AT AT92120661T patent/ATE165620T1/de not_active IP Right Cessation
- 1992-12-03 DK DK92120661T patent/DK0547446T3/da active
- 1992-12-03 EP EP92120661A patent/EP0547446B1/de not_active Expired - Lifetime
- 1992-12-03 ES ES92120661T patent/ES2116306T3/es not_active Expired - Lifetime
- 1992-12-03 DE DE59209310T patent/DE59209310D1/de not_active Expired - Fee Related
- 1992-12-11 CA CA002085191A patent/CA2085191C/en not_active Expired - Fee Related
- 1992-12-15 ZA ZA929719A patent/ZA929719B/xx unknown
- 1992-12-15 KR KR1019920024352A patent/KR100265717B1/ko not_active IP Right Cessation
- 1992-12-15 AR AR92323900A patent/AR248047A1/es active
- 1992-12-15 JP JP4353976A patent/JPH05276942A/ja active Pending
- 1992-12-16 HU HU9203976A patent/HU9203976D0/hu unknown
- 1992-12-16 HU HU9203976A patent/HU215537B/hu not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| AU2968892A (en) | 1993-07-01 |
| HUT65487A (en) | 1994-06-28 |
| CA2085191C (en) | 2003-11-04 |
| HU215537B (hu) | 1999-01-28 |
| MX9206973A (es) | 1993-06-01 |
| ES2116306T3 (es) | 1998-07-16 |
| ATE165620T1 (de) | 1998-05-15 |
| KR930012826A (ko) | 1993-07-21 |
| EP0547446B1 (de) | 1998-04-29 |
| DE4141400A1 (de) | 1993-06-17 |
| KR100265717B1 (ko) | 2000-09-15 |
| EP0547446A2 (de) | 1993-06-23 |
| ZA929719B (en) | 1993-06-14 |
| JPH05276942A (ja) | 1993-10-26 |
| AU660741B2 (en) | 1995-07-06 |
| DE59209310D1 (de) | 1998-06-04 |
| EP0547446A3 (en) | 1994-09-28 |
| CA2085191A1 (en) | 1993-06-17 |
| DK0547446T3 (da) | 1998-12-07 |
| HU9203976D0 (en) | 1993-03-29 |
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