CA2085191A1 - Vaccines based on modified type 1 bovine herpesviruses - Google Patents

Vaccines based on modified type 1 bovine herpesviruses

Info

Publication number
CA2085191A1
CA2085191A1 CA002085191A CA2085191A CA2085191A1 CA 2085191 A1 CA2085191 A1 CA 2085191A1 CA 002085191 A CA002085191 A CA 002085191A CA 2085191 A CA2085191 A CA 2085191A CA 2085191 A1 CA2085191 A1 CA 2085191A1
Authority
CA
Canada
Prior art keywords
vaccines based
modified type
bovine herpesviruses
vaccines
modified
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002085191A
Other languages
French (fr)
Other versions
CA2085191C (en
Inventor
Georg Flob
Walter Strube
Peter Thein
Guenther Keil
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2085191A1 publication Critical patent/CA2085191A1/en
Application granted granted Critical
Publication of CA2085191C publication Critical patent/CA2085191C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2/00—Peptides of undefined number of amino acids; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16711—Varicellovirus, e.g. human herpesvirus 3, Varicella Zoster, pseudorabies
    • C12N2710/16721—Viruses as such, e.g. new isolates, mutants or their genomic sequences
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16711—Varicellovirus, e.g. human herpesvirus 3, Varicella Zoster, pseudorabies
    • C12N2710/16722—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

The present invention relates to vaccines based on type 1 bovine herpesviruses (BHV-1) which contain modifi-cations in regions of their genome which code for non-essential parts of essential proteins. It is possible with the aid of these vaccines to differentiate immunised from non-immunised cattle. The invention furthermore relates to processes for the isolation and preparation of the modified BHV-1 strains, isolation and preparation of the modified proteins and peptides.
CA002085191A 1991-12-16 1992-12-11 Vaccines based on modified type 1 bovine herpesviruses Expired - Fee Related CA2085191C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4141400A DE4141400A1 (en) 1991-12-16 1991-12-16 Vaccines based on modified Bovine herpes viruses type 1
DEP4141400.4 1991-12-16

Publications (2)

Publication Number Publication Date
CA2085191A1 true CA2085191A1 (en) 1993-06-17
CA2085191C CA2085191C (en) 2003-11-04

Family

ID=6447143

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002085191A Expired - Fee Related CA2085191C (en) 1991-12-16 1992-12-11 Vaccines based on modified type 1 bovine herpesviruses

Country Status (13)

Country Link
EP (1) EP0547446B1 (en)
JP (1) JPH05276942A (en)
KR (1) KR100265717B1 (en)
AR (1) AR248047A1 (en)
AT (1) ATE165620T1 (en)
AU (1) AU660741B2 (en)
CA (1) CA2085191C (en)
DE (2) DE4141400A1 (en)
DK (1) DK0547446T3 (en)
ES (1) ES2116306T3 (en)
HU (2) HU215537B (en)
MX (1) MX9206973A (en)
ZA (1) ZA929719B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5783195A (en) * 1991-07-18 1998-07-21 Syntro Corporation Recombinant infectious bovine rhinotracheitis virus S-IBR-052 and uses thereof
US6410033B1 (en) 1987-07-27 2002-06-25 Syntro Corporation Recombinant infectious bovine rhinotracheitis virus
NL9100989A (en) * 1991-06-07 1993-01-04 Stichting Centr Diergeneeskund BOVINE HERPESVIRUS TYPE 1 DELETION MUTANTS, VACCINES BASED ON THESE, DIAGNOSTIC KITS FOR DETECTION OF BOVINE HERPESVIRUS TYPE 1.
CA2136381A1 (en) * 1993-11-23 1995-05-24 Gunther Keil Vector vaccines of bovine herpesvirus 1
EP0663403A1 (en) * 1993-11-23 1995-07-19 Akzo Nobel N.V. Vector vaccines of bovine herpesvirus I

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4992051A (en) * 1987-11-03 1991-02-12 Novagene, Inc. Infectious bovine rhinotracheitis virus mutants, methods for the production of same and methods for the use of same
NL9100989A (en) * 1991-06-07 1993-01-04 Stichting Centr Diergeneeskund BOVINE HERPESVIRUS TYPE 1 DELETION MUTANTS, VACCINES BASED ON THESE, DIAGNOSTIC KITS FOR DETECTION OF BOVINE HERPESVIRUS TYPE 1.

Also Published As

Publication number Publication date
AU660741B2 (en) 1995-07-06
KR930012826A (en) 1993-07-21
HU9203976D0 (en) 1993-03-29
CA2085191C (en) 2003-11-04
ZA929719B (en) 1993-06-14
HUT65487A (en) 1994-06-28
ATE165620T1 (en) 1998-05-15
DK0547446T3 (en) 1998-12-07
DE4141400A1 (en) 1993-06-17
JPH05276942A (en) 1993-10-26
ES2116306T3 (en) 1998-07-16
EP0547446B1 (en) 1998-04-29
EP0547446A3 (en) 1994-09-28
AU2968892A (en) 1993-07-01
HU215537B (en) 1999-01-28
AR248047A1 (en) 1995-05-31
KR100265717B1 (en) 2000-09-15
DE59209310D1 (en) 1998-06-04
MX9206973A (en) 1993-06-01
EP0547446A2 (en) 1993-06-23

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Legal Events

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