AR246948A1 - Procedimiento para la obtencion del acido (s)-4-(2-bromobenzoil)-5-hidroxi-benzociclobuten-1-carboxilico. - Google Patents
Procedimiento para la obtencion del acido (s)-4-(2-bromobenzoil)-5-hidroxi-benzociclobuten-1-carboxilico.Info
- Publication number
- AR246948A1 AR246948A1 AR91319321A AR31932191A AR246948A1 AR 246948 A1 AR246948 A1 AR 246948A1 AR 91319321 A AR91319321 A AR 91319321A AR 31932191 A AR31932191 A AR 31932191A AR 246948 A1 AR246948 A1 AR 246948A1
- Authority
- AR
- Argentina
- Prior art keywords
- hydroxy
- procedure
- obtaining
- bromobenzoil
- benzociclobuten
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C62/00—Compounds having carboxyl groups bound to carbon atoms of rings other than six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C62/30—Unsaturated compounds
- C07C62/38—Unsaturated compounds containing keto groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/42—Separation; Purification; Stabilisation; Use of additives
- C07C51/487—Separation; Purification; Stabilisation; Use of additives by treatment giving rise to chemical modification
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DEL ACIDO (S)-4-(2-BROMOBENZOIL)-5-HIDROXI- BENZOCICLOBUTEN-1-CARBOXILICO, DE LA FORMULA (I), EN FORMA LIBRE O EN FORMA DE SAL, DONDE SE HACE REACCIONAR EN UN SOLVENTE ALCOHOLICO, ACIDO 4-(2- BROMOBENZOIL)-5-HIDROXI-BENZOCICLOBUTEN-1-CARBOXILICO RACEMICO CON QUININA, CALENTANDO; AISLAR DE LA MEZCLA REACCIONANTE EL PRODUCTO INMEDIATO DE LA REACCION QUE ES LASAL QUININICA CRISTALINA DEL ACIDO (S)-4-(2-BROMOBENZOIL) 5-HIDROXI-BENZOCICLOBUTEN-1-CARBOXILICO Y DE ESA SAL, DE MANERA USUAL, LIBERAR POR TRATAMIENTO CON ACIDOS, EL ACIDO (S)-4-(2-BROMOBENZOIL)-5- HIDROXI-BENZOCICLOBUTEN-1-CARBOXILICO, QUE PUEDE SALIFICARSE SI SE DESEA.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH101090 | 1990-03-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR246948A1 true AR246948A1 (es) | 1994-10-31 |
Family
ID=4200343
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AR91319321A AR246948A1 (es) | 1990-03-27 | 1991-03-26 | Procedimiento para la obtencion del acido (s)-4-(2-bromobenzoil)-5-hidroxi-benzociclobuten-1-carboxilico. |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US5177257A (es) |
| EP (1) | EP0478721B1 (es) |
| JP (1) | JPH05500518A (es) |
| KR (1) | KR920701111A (es) |
| CN (1) | CN1055175A (es) |
| AR (1) | AR246948A1 (es) |
| AT (1) | ATE127444T1 (es) |
| AU (1) | AU643981B2 (es) |
| CA (1) | CA2055602A1 (es) |
| CS (1) | CS80891A2 (es) |
| DE (1) | DE59106417D1 (es) |
| ES (1) | ES2077219T3 (es) |
| FI (1) | FI915542A0 (es) |
| HU (1) | HUT60233A (es) |
| IE (1) | IE911003A1 (es) |
| IL (1) | IL97618A0 (es) |
| MX (1) | MX25042A (es) |
| MY (1) | MY104641A (es) |
| PL (1) | PL293021A1 (es) |
| PT (1) | PT97129A (es) |
| WO (1) | WO1991014671A1 (es) |
| YU (1) | YU53691A (es) |
| ZA (1) | ZA912262B (es) |
| ZW (1) | ZW3391A1 (es) |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR242947A1 (es) * | 1983-06-15 | 1993-06-30 | Ciba Geigy | Procedimiento para la obtencion de derivados de acidos 4-benzoil-5-hidroxi-benzoilciclobuten-1-carboxilico y sus sales. |
-
1991
- 1991-03-19 KR KR1019910701678A patent/KR920701111A/ko not_active Application Discontinuation
- 1991-03-19 PL PL29302191A patent/PL293021A1/xx unknown
- 1991-03-19 US US07/776,385 patent/US5177257A/en not_active Expired - Fee Related
- 1991-03-19 HU HU914081A patent/HUT60233A/hu unknown
- 1991-03-19 DE DE59106417T patent/DE59106417D1/de not_active Expired - Fee Related
- 1991-03-19 CA CA002055602A patent/CA2055602A1/en not_active Abandoned
- 1991-03-19 AT AT91905069T patent/ATE127444T1/de not_active IP Right Cessation
- 1991-03-19 ES ES91905069T patent/ES2077219T3/es not_active Expired - Lifetime
- 1991-03-19 JP JP3505146A patent/JPH05500518A/ja active Pending
- 1991-03-19 EP EP91905069A patent/EP0478721B1/de not_active Expired - Lifetime
- 1991-03-19 AU AU73459/91A patent/AU643981B2/en not_active Ceased
- 1991-03-19 WO PCT/CH1991/000064 patent/WO1991014671A1/de active IP Right Grant
- 1991-03-20 IL IL97618A patent/IL97618A0/xx unknown
- 1991-03-25 MY MYPI91000492A patent/MY104641A/en unknown
- 1991-03-25 PT PT97129A patent/PT97129A/pt not_active Application Discontinuation
- 1991-03-25 MX MX2504291A patent/MX25042A/es unknown
- 1991-03-26 YU YU53691A patent/YU53691A/sh unknown
- 1991-03-26 CN CN91101858A patent/CN1055175A/zh active Pending
- 1991-03-26 ZA ZA912262A patent/ZA912262B/xx unknown
- 1991-03-26 AR AR91319321A patent/AR246948A1/es active
- 1991-03-26 ZW ZW33/91A patent/ZW3391A1/xx unknown
- 1991-03-26 CS CS91808A patent/CS80891A2/cs unknown
- 1991-03-26 IE IE100391A patent/IE911003A1/en unknown
- 1991-11-25 FI FI915542A patent/FI915542A0/fi not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| US5177257A (en) | 1993-01-05 |
| MY104641A (en) | 1994-04-30 |
| ZA912262B (en) | 1991-11-27 |
| PL293021A1 (en) | 1992-12-28 |
| YU53691A (sh) | 1994-04-05 |
| CS80891A2 (en) | 1991-11-12 |
| DE59106417D1 (de) | 1995-10-12 |
| IL97618A0 (en) | 1992-06-21 |
| HU914081D0 (en) | 1992-07-28 |
| EP0478721B1 (de) | 1995-09-06 |
| ES2077219T3 (es) | 1995-11-16 |
| AU7345991A (en) | 1991-10-21 |
| IE911003A1 (en) | 1991-10-09 |
| CN1055175A (zh) | 1991-10-09 |
| KR920701111A (ko) | 1992-08-11 |
| PT97129A (pt) | 1991-11-29 |
| CA2055602A1 (en) | 1991-09-28 |
| ATE127444T1 (de) | 1995-09-15 |
| ZW3391A1 (en) | 1991-10-30 |
| FI915542A0 (fi) | 1991-11-25 |
| JPH05500518A (ja) | 1993-02-04 |
| EP0478721A1 (de) | 1992-04-08 |
| AU643981B2 (en) | 1993-12-02 |
| WO1991014671A1 (de) | 1991-10-03 |
| HUT60233A (en) | 1992-08-28 |
| MX25042A (es) | 1993-12-01 |
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