AR227941A1 - Procedimiento para la preparacion de 4-(2-imidazolil)piridinas 2-sustituidas utiles como agente antiulcerante - Google Patents
Procedimiento para la preparacion de 4-(2-imidazolil)piridinas 2-sustituidas utiles como agente antiulceranteInfo
- Publication number
- AR227941A1 AR227941A1 AR287072A AR28707281A AR227941A1 AR 227941 A1 AR227941 A1 AR 227941A1 AR 287072 A AR287072 A AR 287072A AR 28707281 A AR28707281 A AR 28707281A AR 227941 A1 AR227941 A1 AR 227941A1
- Authority
- AR
- Argentina
- Prior art keywords
- piridines
- imidazolil
- procedure
- preparation
- ulcerant
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
- C07D213/53—Nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
- C07D213/46—Oxygen atoms
- C07D213/51—Acetal radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/61—Halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/73—Unsubstituted amino or imino radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/84—Nitriles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/197,388 US4302464A (en) | 1980-10-16 | 1980-10-16 | Imidazolylpyridine therapeutic agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR227941A1 true AR227941A1 (es) | 1982-12-30 |
Family
ID=22729208
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AR287072A AR227941A1 (es) | 1980-10-16 | 1981-10-13 | Procedimiento para la preparacion de 4-(2-imidazolil)piridinas 2-sustituidas utiles como agente antiulcerante |
| AR290585A AR228678A1 (es) | 1980-10-16 | 1982-09-09 | Procedimiento para la preparacion de 4-(2-imidazolil)piridinas 2-sustituidas utiles como agentes antiulcerantes |
| AR290584A AR228677A1 (es) | 1980-10-16 | 1982-09-09 | Procedimiento para la preparacion de 4-(2-imidazolil)piridinas 2-sustituidas utiles como agentes antiulcerantes |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AR290585A AR228678A1 (es) | 1980-10-16 | 1982-09-09 | Procedimiento para la preparacion de 4-(2-imidazolil)piridinas 2-sustituidas utiles como agentes antiulcerantes |
| AR290584A AR228677A1 (es) | 1980-10-16 | 1982-09-09 | Procedimiento para la preparacion de 4-(2-imidazolil)piridinas 2-sustituidas utiles como agentes antiulcerantes |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US4302464A (sv) |
| EP (1) | EP0051371B1 (sv) |
| JP (1) | JPS5795983A (sv) |
| KR (1) | KR850001226B1 (sv) |
| AR (3) | AR227941A1 (sv) |
| AT (1) | ATE9156T1 (sv) |
| AU (1) | AU524257B2 (sv) |
| CA (1) | CA1175435A (sv) |
| DE (1) | DE3165786D1 (sv) |
| DK (1) | DK457181A (sv) |
| ES (3) | ES506281A0 (sv) |
| FI (1) | FI72974C (sv) |
| GR (1) | GR75096B (sv) |
| IE (1) | IE51683B1 (sv) |
| IL (1) | IL64054A (sv) |
| PH (1) | PH16715A (sv) |
| PT (1) | PT73835B (sv) |
| YU (3) | YU42734B (sv) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4463005A (en) * | 1981-03-18 | 1984-07-31 | Imperial Chemical Industries Plc | Bicyclic guanidines |
| US4510151A (en) * | 1984-02-10 | 1985-04-09 | Usv Pharmaceutical Corporation | Pyridinylimidazole pharmaceutical composition |
| SE8405588D0 (sv) * | 1984-11-08 | 1984-11-08 | Haessle Ab | New compounds |
| DK337086A (da) * | 1985-08-12 | 1987-02-13 | Hoffmann La Roche | Benzimidazolderivater |
| US4911753A (en) * | 1987-01-21 | 1990-03-27 | American Cyanamid Company | Herbicidal 2-(2-imidazolin-2-yl)fluoroalkoxy-, alkenyloxy-, and alkynyloxypyridines and quinolines |
| FR2780973B1 (fr) | 1998-07-09 | 2001-10-05 | Hoechst Marion Roussel Inc | Procede de preparation du 4-(3-pyridinyl)-1h-imidazole, et les intermediaires mis en oeuvre |
| AR039241A1 (es) | 2002-04-04 | 2005-02-16 | Biogen Inc | Heteroarilos trisustituidos y metodos para su produccion y uso de los mismos |
| UA80296C2 (en) * | 2002-09-06 | 2007-09-10 | Biogen Inc | Imidazolopyridines and methods of making and using the same |
| UA80295C2 (en) | 2002-09-06 | 2007-09-10 | Biogen Inc | Pyrazolopyridines and using the same |
| CL2004000234A1 (es) * | 2003-02-12 | 2005-04-15 | Biogen Idec Inc | Compuestos derivados 3-(piridin-2-il)-4-heteroaril-pirazol sustituidos, antagonistas de aik5 y/o aik4; composicion farmaceutica y uso del compuesto en el tratamiento de desordenes fibroticos como esclerodermia, lupus nefritico, cicatrizacion de herid |
| KR100914375B1 (ko) * | 2007-06-26 | 2009-08-28 | 한국원자력연구원 | 초음파를 이용한 균열 간극의 크기 산출방법 |
| EP4196793A1 (en) | 2020-08-11 | 2023-06-21 | Université de Strasbourg | H2 blockers targeting liver macrophages for the prevention and treatment of liver disease and cancer |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5343958B2 (sv) * | 1972-07-29 | 1978-11-24 |
-
1980
- 1980-10-16 US US06/197,388 patent/US4302464A/en not_active Expired - Lifetime
-
1981
- 1981-10-13 DE DE8181304754T patent/DE3165786D1/de not_active Expired
- 1981-10-13 JP JP56163371A patent/JPS5795983A/ja active Granted
- 1981-10-13 AR AR287072A patent/AR227941A1/es active
- 1981-10-13 AT AT81304754T patent/ATE9156T1/de not_active IP Right Cessation
- 1981-10-13 GR GR66265A patent/GR75096B/el unknown
- 1981-10-13 EP EP81304754A patent/EP0051371B1/en not_active Expired
- 1981-10-14 IE IE2411/81A patent/IE51683B1/en unknown
- 1981-10-15 PH PH26350A patent/PH16715A/en unknown
- 1981-10-15 FI FI813214A patent/FI72974C/sv not_active IP Right Cessation
- 1981-10-15 DK DK457181A patent/DK457181A/da not_active Application Discontinuation
- 1981-10-15 AU AU76390/81A patent/AU524257B2/en not_active Ceased
- 1981-10-15 CA CA000387974A patent/CA1175435A/en not_active Expired
- 1981-10-15 ES ES506281A patent/ES506281A0/es active Granted
- 1981-10-15 IL IL64054A patent/IL64054A/xx unknown
- 1981-10-15 YU YU2471/81A patent/YU42734B/xx unknown
- 1981-10-16 KR KR1019810003955A patent/KR850001226B1/ko active
- 1981-10-16 PT PT73835A patent/PT73835B/pt unknown
-
1982
- 1982-08-25 ES ES515244A patent/ES515244A0/es active Granted
- 1982-08-25 ES ES515243A patent/ES8306741A1/es not_active Expired
- 1982-09-09 AR AR290585A patent/AR228678A1/es active
- 1982-09-09 AR AR290584A patent/AR228677A1/es active
-
1983
- 1983-08-22 YU YU1724/83A patent/YU42876B/xx unknown
- 1983-08-22 YU YU1725/83A patent/YU42877B/xx unknown
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