AR127561A1 - Compuestos para el tratamiento de trastornos dependientes de cinasas - Google Patents
Compuestos para el tratamiento de trastornos dependientes de cinasasInfo
- Publication number
- AR127561A1 AR127561A1 ARP220103011A ARP220103011A AR127561A1 AR 127561 A1 AR127561 A1 AR 127561A1 AR P220103011 A ARP220103011 A AR P220103011A AR P220103011 A ARP220103011 A AR P220103011A AR 127561 A1 AR127561 A1 AR 127561A1
- Authority
- AR
- Argentina
- Prior art keywords
- compound
- formula
- compounds
- treatment
- pharmaceutically acceptable
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 7
- 108091000080 Phosphotransferase Proteins 0.000 title 1
- 230000001419 dependent effect Effects 0.000 title 1
- 102000020233 phosphotransferase Human genes 0.000 title 1
- 150000003839 salts Chemical class 0.000 abstract 3
- PLIKAWJENQZMHA-UHFFFAOYSA-N 4-aminophenol Chemical compound NC1=CC=C(O)C=C1 PLIKAWJENQZMHA-UHFFFAOYSA-N 0.000 abstract 2
- 239000000356 contaminant Substances 0.000 abstract 2
- 239000008380 degradant Substances 0.000 abstract 2
- 229940121358 tyrosine kinase inhibitor Drugs 0.000 abstract 2
- 239000005483 tyrosine kinase inhibitor Substances 0.000 abstract 2
- KRZCOLNOCZKSDF-UHFFFAOYSA-N 4-fluoroaniline Chemical compound NC1=CC=C(F)C=C1 KRZCOLNOCZKSDF-UHFFFAOYSA-N 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163275255P | 2021-11-03 | 2021-11-03 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR127561A1 true AR127561A1 (es) | 2024-02-07 |
Family
ID=84462825
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP220103011A AR127561A1 (es) | 2021-11-03 | 2022-11-02 | Compuestos para el tratamiento de trastornos dependientes de cinasas |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20250051284A1 (https=) |
| EP (1) | EP4426678A1 (https=) |
| JP (1) | JP2024539721A (https=) |
| CN (1) | CN118176182A (https=) |
| AR (1) | AR127561A1 (https=) |
| AU (1) | AU2022383160A1 (https=) |
| CA (1) | CA3235602A1 (https=) |
| TW (1) | TW202334090A (https=) |
| WO (1) | WO2023081253A1 (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN117402114A (zh) * | 2018-01-26 | 2024-01-16 | 埃克塞里艾克西斯公司 | 用于治疗激酶依赖性病症的化合物 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN117402114A (zh) * | 2018-01-26 | 2024-01-16 | 埃克塞里艾克西斯公司 | 用于治疗激酶依赖性病症的化合物 |
| KR102828472B1 (ko) * | 2018-12-13 | 2025-07-03 | 엑셀리시스, 인코포레이티드 | 키나아제 억제제의 결정질 형태 및 염 형태 |
| MX2021014773A (es) * | 2019-06-03 | 2022-01-18 | Exelixis Inc | Formas de sales cristalinas de un inhibidor de cinasas. |
| CN115461328B (zh) * | 2020-04-30 | 2025-11-07 | 埃克塞里艾克西斯公司 | 用于制备激酶抑制剂的方法 |
| JP2023548855A (ja) * | 2020-11-05 | 2023-11-21 | エグゼリクシス， インコーポレイテッド | キナーゼ阻害剤の医薬組成物 |
-
2022
- 2022-11-02 TW TW111141900A patent/TW202334090A/zh unknown
- 2022-11-02 AR ARP220103011A patent/AR127561A1/es unknown
- 2022-11-03 US US18/706,757 patent/US20250051284A1/en active Pending
- 2022-11-03 CN CN202280073218.2A patent/CN118176182A/zh active Pending
- 2022-11-03 CA CA3235602A patent/CA3235602A1/en active Pending
- 2022-11-03 AU AU2022383160A patent/AU2022383160A1/en active Pending
- 2022-11-03 EP EP22821747.7A patent/EP4426678A1/en active Pending
- 2022-11-03 JP JP2024526617A patent/JP2024539721A/ja active Pending
- 2022-11-03 WO PCT/US2022/048770 patent/WO2023081253A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| CN118176182A (zh) | 2024-06-11 |
| WO2023081253A1 (en) | 2023-05-11 |
| CA3235602A1 (en) | 2023-05-11 |
| US20250051284A1 (en) | 2025-02-13 |
| AU2022383160A1 (en) | 2024-05-02 |
| JP2024539721A (ja) | 2024-10-29 |
| EP4426678A1 (en) | 2024-09-11 |
| TW202334090A (zh) | 2023-09-01 |
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