AR117964A1 - Método para transferir un proceso de producción por lotes a un proceso de producción continua - Google Patents

Método para transferir un proceso de producción por lotes a un proceso de producción continua

Info

Publication number
AR117964A1
AR117964A1 ARP200100094A ARP200100094A AR117964A1 AR 117964 A1 AR117964 A1 AR 117964A1 AR P200100094 A ARP200100094 A AR P200100094A AR P200100094 A ARP200100094 A AR P200100094A AR 117964 A1 AR117964 A1 AR 117964A1
Authority
AR
Argentina
Prior art keywords
production process
transfer
continuous production
batch production
batch
Prior art date
Application number
ARP200100094A
Other languages
English (en)
Inventor
Lobedann Martin Dr
Laura David
Lenz Juergen Dr
Sven Claen
Maiser Benjamin Dr
Borchert Sven Dr
- Dr Schwan Peter Oliver
Budde Bastian Dr
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of AR117964A1 publication Critical patent/AR117964A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/18—Ion-exchange chromatography
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
    • B01D15/1864—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns using two or more columns
    • B01D15/1871—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns using two or more columns placed in series
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction
    • B01D15/361—Ion-exchange
    • B01D15/362—Cation-exchange
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction
    • B01D15/361—Ion-exchange
    • B01D15/363—Anion-exchange
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 - B01D15/36
    • B01D15/3804—Affinity chromatography
    • B01D15/3809—Affinity chromatography of the antigen-antibody type, e.g. protein A, G, L chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/34—Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065—Purification, fragmentation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Water Supply & Treatment (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

En la presente se describe un método para transferir el proceso de producción por lotes de un anticuerpo monoclonal a un proceso de producción continua para el mismo anticuerpo monoclonal.
ARP200100094A 2019-01-15 2020-01-14 Método para transferir un proceso de producción por lotes a un proceso de producción continua AR117964A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP19151756.4A EP3683231A1 (en) 2019-01-15 2019-01-15 Method for transferring a batch production process to a continuous production process

Publications (1)

Publication Number Publication Date
AR117964A1 true AR117964A1 (es) 2021-09-08

Family

ID=65278167

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP200100094A AR117964A1 (es) 2019-01-15 2020-01-14 Método para transferir un proceso de producción por lotes a un proceso de producción continua

Country Status (13)

Country Link
US (1) US20220073560A1 (es)
EP (2) EP3683231A1 (es)
JP (1) JP2022522966A (es)
KR (1) KR20210116467A (es)
CN (1) CN113330028A (es)
AR (1) AR117964A1 (es)
AU (1) AU2020209371A1 (es)
BR (1) BR112021011026A2 (es)
CA (1) CA3126412A1 (es)
IL (1) IL284038A (es)
SG (1) SG11202107199TA (es)
TW (1) TW202041531A (es)
WO (1) WO2020148119A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021197248A1 (zh) * 2020-03-30 2021-10-07 上海复宏汉霖生物技术股份有限公司 连续纯化生物制药产品的系统和方法
AU2022233131A1 (en) * 2021-03-10 2023-08-17 Amgen Inc. Parallel chromatography systems and methods

Also Published As

Publication number Publication date
EP3683231A1 (en) 2020-07-22
CN113330028A (zh) 2021-08-31
AU2020209371A1 (en) 2021-07-08
IL284038A (en) 2021-08-31
EP3911674A1 (en) 2021-11-24
BR112021011026A2 (pt) 2021-08-31
KR20210116467A (ko) 2021-09-27
SG11202107199TA (en) 2021-07-29
JP2022522966A (ja) 2022-04-21
WO2020148119A1 (en) 2020-07-23
TW202041531A (zh) 2020-11-16
US20220073560A1 (en) 2022-03-10
CA3126412A1 (en) 2020-07-23

Similar Documents

Publication Publication Date Title
AR117964A1 (es) Método para transferir un proceso de producción por lotes a un proceso de producción continua
BR112014018961A8 (pt) Anticorpo isolado, anticorpo biespecífico, fragmento, ácido nucleico isolado, vetor, célula hospedeira, método de produção de anticorpos, composição farmacêutica, uso do anticorpo, método de tratamento, método de inibição e artigo industrializado
CL2019002658A1 (es) Composiciones optimizadas de anticuerpos para el tratamiento de desórdenes oculares.
SA517382081B1 (ar) عملية تقطير لإنتاج حمض أكريليك
UY38739A (es) Proteínas multiespecíficas
CO2019011458A2 (es) Anticuerpo monoclonal para pd-l1
EA201990894A9 (ru) Анти-pd-1/анти-her2 гетеродимерное биспецифическое антитело со структурой природного антитела и способ его получения
CL2018002094A1 (es) Un proceso para preparar compuesto de pirrolo[3,2–d]pirimidina y su intermediario
CL2020000160A1 (es) Proceso de deshidrogenación y cracking térmico integrado para la producción de olefinas
BR112022022800A2 (pt) Métodos para tratamento de mieloma múltiplo
CL2023001049A1 (es) Procedimiento para la fabricación de compuestos orgánicos
CL2021001363A1 (es) Métodos de tratamiento de enfermedades con inhibidores de magl.
CL2020000190A1 (es) Inhibidores de ror-gamma.
CO2021004529A2 (es) Proceso de elaboración de alfa-cetoglutarato de calcio referencia cruzada con solicitudes relacionadas
GB2593104B (en) System for optimization of hydrocarbon production
MX2019006123A (es) Metodo para glicomanipulacion in vitro de anticuerpos.
CL2019002164A1 (es) Aparato y proceso de flujo continuo para la producción de derivado de ácido borónico.
EP3897723A4 (en) PRODUCTION OF MONOCLONAL ANTIBODY SPECIFIC TO THE CD24 CELLULAR RECEPTOR
MX2021012754A (es) Proceso para la produccion de acido metanosulfonico anhidro a partir de metano y so3.
CL2019003162A1 (es) Método de producción de ácido 1–aminociclopropancarboxílico no hidrato.
EP3634994A4 (en) SURFACE LOAD ENGINEERING PROCESSES FOR THE PRODUCTION OF A BISPECIFIC ANTIBODY
SG11202011553SA (en) Method for transfer of a thin layer of silicon
CL2021000902A1 (es) Método para la fabricación de gemas sintéticas.
CO2018010286A2 (es) Método para la purificación de proteínas
BR112022006050A2 (pt) Processo para produção de ácido alcanossulfônico