AR115049A1 - Carboxialquil quitosano - Google Patents
Carboxialquil quitosanoInfo
- Publication number
- AR115049A1 AR115049A1 ARP180103294A ARP180103294A AR115049A1 AR 115049 A1 AR115049 A1 AR 115049A1 AR P180103294 A ARP180103294 A AR P180103294A AR P180103294 A ARP180103294 A AR P180103294A AR 115049 A1 AR115049 A1 AR 115049A1
- Authority
- AR
- Argentina
- Prior art keywords
- carboxyalkyl
- chitosan
- glucosamine units
- mol
- defined according
- Prior art date
Links
- 125000004181 carboxyalkyl group Chemical group 0.000 abstract 6
- 229920001661 Chitosan Polymers 0.000 abstract 4
- MSWZFWKMSRAUBD-IVMDWMLBSA-N glucosamine group Chemical group OC1[C@H](N)[C@@H](O)[C@H](O)[C@H](O1)CO MSWZFWKMSRAUBD-IVMDWMLBSA-N 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 abstract 1
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 abstract 1
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 abstract 1
- 229930195725 Mannitol Natural products 0.000 abstract 1
- OVRNDRQMDRJTHS-FMDGEEDCSA-N N-acetyl-beta-D-glucosamine Chemical group CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O OVRNDRQMDRJTHS-FMDGEEDCSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 239000006172 buffering agent Substances 0.000 abstract 1
- 230000002538 fungal effect Effects 0.000 abstract 1
- 239000000594 mannitol Substances 0.000 abstract 1
- 235000010355 mannitol Nutrition 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 239000000600 sorbitol Substances 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
- 238000006467 substitution reaction Methods 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/736—Chitin; Chitosan; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
- C08B37/0024—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid beta-D-Glucans; (beta-1,3)-D-Glucans, e.g. paramylon, coriolan, sclerotan, pachyman, callose, scleroglucan, schizophyllan, laminaran, lentinan or curdlan; (beta-1,6)-D-Glucans, e.g. pustulan; (beta-1,4)-D-Glucans; (beta-1,3)(beta-1,4)-D-Glucans, e.g. lichenan; Derivatives thereof
- C08B37/0027—2-Acetamido-2-deoxy-beta-glucans; Derivatives thereof
- C08B37/003—Chitin, i.e. 2-acetamido-2-deoxy-(beta-1,4)-D-glucan or N-acetyl-beta-1,4-D-glucosamine; Chitosan, i.e. deacetylated product of chitin or (beta-1,4)-D-glucosamine; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/716—Glucans
- A61K31/722—Chitin, chitosan
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/20—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
- C08L5/08—Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2400/00—Materials characterised by their function or physical properties
- A61L2400/06—Flowable or injectable implant compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/06—Materials or treatment for tissue regeneration for cartilage reconstruction, e.g. meniscus
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dermatology (AREA)
- Pharmacology & Pharmacy (AREA)
- Polymers & Plastics (AREA)
- Engineering & Computer Science (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Materials Engineering (AREA)
- Biochemistry (AREA)
- Birds (AREA)
- Gerontology & Geriatric Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Physical Education & Sports Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Cosmetics (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Absorbent Articles And Supports Therefor (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Materials For Medical Uses (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Reivindicación 1: Carboxialquilo de quitosano de origen fúngico caracterizado porque presenta unidades glucosamina, unidades N-acetil-glucosamina, y unidades glucosamina sustituidas por un grupo carboxialquilo, y dicho carboxialquilo de quitosano presenta, de preferencia, un grado de sustitución por un grupo carboxialquilo superior al 20%, expresado en número de mol del sustituyente, con respecto al número de mol de unidades totales. Reivindicación 16: Procedimiento de preparación de una composición caracterizado porque comprende un carboxialquilo de quitosano definido de acuerdo con una cualquiera de las reivindicaciones 8 a 14, y dicho procedimiento comprende: la disolución de un carboxialquilo de quitosano definido de acuerdo con una cualquiera de las reivindicaciones 1 a 9 en una solución acuosa, de preferencia agua, eventualmente tamponada, de preferencia a pH comprendido entre 6,2 y 8,5, y de preferencia entre 6,5 y 7,5; el ajuste eventual del pH a un pH deseado, en general al pH fisiológico para la aplicación prevista, por ejemplo, por adición de un agente tamponante, de una base o de un ácido; la adición eventual de otros excipientes como, por ejemplo, un azúcar reductor, por ejemplo, sorbitol o manitol; el ajuste eventual de la osmolalidad final de la composición.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR1761323A FR3074044B1 (fr) | 2017-11-28 | 2017-11-28 | Carboxyalkyl chitosane |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR115049A1 true AR115049A1 (es) | 2020-11-25 |
Family
ID=61802047
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP180103294A AR115049A1 (es) | 2017-11-28 | 2018-11-12 | Carboxialquil quitosano |
Country Status (20)
| Country | Link |
|---|---|
| US (2) | US11667727B2 (es) |
| EP (1) | EP3510051B2 (es) |
| AR (1) | AR115049A1 (es) |
| CA (1) | CA3082557A1 (es) |
| CL (1) | CL2020001323A1 (es) |
| DK (1) | DK3510051T3 (es) |
| EA (1) | EA202091062A1 (es) |
| ES (1) | ES2781787T5 (es) |
| FI (1) | FI3510051T4 (es) |
| FR (1) | FR3074044B1 (es) |
| HR (1) | HRP20200411T4 (es) |
| MA (1) | MA49811A1 (es) |
| MX (1) | MX2020005002A (es) |
| PE (1) | PE20210441A1 (es) |
| PL (1) | PL3510051T5 (es) |
| PT (1) | PT3510051T (es) |
| SG (1) | SG11202005039WA (es) |
| TN (1) | TN2020000070A1 (es) |
| UA (1) | UA126087C2 (es) |
| WO (1) | WO2019105719A1 (es) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112111022B (zh) * | 2020-10-10 | 2021-06-04 | 山东一滕新材料股份有限公司 | 一种改性壳聚糖及其制备方法、瓷砖胶添加剂及其应用 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4619995A (en) * | 1984-12-24 | 1986-10-28 | Nova Chem Limited | N,O-carboxymethyl chitosan and preparative method therefor |
| US5679658A (en) * | 1995-05-08 | 1997-10-21 | Chitogenics, Inc. | N,O-carbonxymethylchitosan for prevention of surgical adhesions |
| DE19725037B4 (de) | 1997-06-13 | 2004-08-05 | Cognis Deutschland Gmbh & Co. Kg | Chitinderivate, Verfahren zu deren Herstellung und deren Verwendung |
| US6645947B1 (en) * | 1999-05-20 | 2003-11-11 | Chitogenics, Inc. | Adhesive N, O-carboxymethylchitosan coatings which inhibit attachment of substrate-dependent cells and proteins |
| BE1014638A6 (fr) | 2002-02-12 | 2004-02-03 | Univ Liege | Methode de preparation de derives de la paroi cellulaire a partir de biomasse. |
| CN1193044C (zh) | 2003-01-09 | 2005-03-16 | 武汉大学 | 羧甲基壳聚糖的制备方法 |
| EP1691779A4 (en) | 2003-11-24 | 2009-01-21 | Optimer Pharmaceuticals Inc | TREATMENT OF A STATE IN A MAMMALIAN WITH THE ADMINISTRATION OF COMPOUNDS AND APPLICATION METHOD THEREFOR |
| BE1016383A3 (fr) | 2004-12-15 | 2006-10-03 | Physiol | Composition polymere pour lentille intraoculaire. |
| CN102688195B (zh) | 2012-06-06 | 2014-01-08 | 中国海洋大学 | 一种具有pH敏感性的包载盐酸阿霉素的壳聚糖羧甲基壳聚糖纳米缓释微粒的制备方法 |
| CN103937014B (zh) | 2014-04-10 | 2016-05-25 | 北京爱美客生物科技有限公司 | 壳聚糖双网络快速响应型可注射水凝胶及其制备方法 |
| FR3024362A1 (fr) | 2014-08-01 | 2016-02-05 | Synolyne Pharma Sa | Composition thermogelifiable sterilisee |
| FR3024363B1 (fr) * | 2014-08-01 | 2018-08-10 | Synolyne Pharma | Composition thermogelifiable |
| FR3029116B1 (fr) | 2014-12-01 | 2018-03-30 | Advanced Chitosan Solutions Biotech | Procede d'obtention d'un gel de cartilage pour la reparation cartilagineuse, comprenant du chitosane et des chondrocytes |
| FR3038837B1 (fr) | 2015-07-13 | 2017-08-18 | Synolyne Pharma | Chitosane pour melange avec un fluide coagulable |
| FR3038838B1 (fr) | 2015-07-13 | 2017-08-18 | Synolyne Pharma | Chitosane pour melange avec un fluide coagulable |
| CN106474569B (zh) | 2016-12-02 | 2019-04-09 | 上海其胜生物制剂有限公司 | 一种羧甲基几丁质临界水凝胶的制备方法 |
| CN107325306B (zh) | 2017-06-13 | 2019-10-25 | 爱美客技术发展股份有限公司 | 壳聚糖或其衍生物多重交联凝胶和制备方法 |
| FR3116534B1 (fr) | 2020-11-23 | 2023-12-22 | Kiomed Pharma | Billes à base de chitosane, préparation, compositions et applications |
-
2017
- 2017-11-28 FR FR1761323A patent/FR3074044B1/fr active Active
-
2018
- 2018-11-09 PT PT187997739T patent/PT3510051T/pt unknown
- 2018-11-09 UA UAA202003180A patent/UA126087C2/uk unknown
- 2018-11-09 PE PE2020000623A patent/PE20210441A1/es unknown
- 2018-11-09 CA CA3082557A patent/CA3082557A1/fr active Pending
- 2018-11-09 HR HRP20200411TT patent/HRP20200411T4/hr unknown
- 2018-11-09 ES ES18799773T patent/ES2781787T5/es active Active
- 2018-11-09 DK DK18799773.9T patent/DK3510051T3/da active
- 2018-11-09 TN TNP/2020/000070A patent/TN2020000070A1/fr unknown
- 2018-11-09 FI FIEP18799773.9T patent/FI3510051T4/fr active
- 2018-11-09 EP EP18799773.9A patent/EP3510051B2/fr active Active
- 2018-11-09 WO PCT/EP2018/080767 patent/WO2019105719A1/fr active Application Filing
- 2018-11-09 MA MA49811A patent/MA49811A1/fr unknown
- 2018-11-09 MX MX2020005002A patent/MX2020005002A/es unknown
- 2018-11-09 EA EA202091062A patent/EA202091062A1/ru unknown
- 2018-11-09 SG SG11202005039WA patent/SG11202005039WA/en unknown
- 2018-11-09 PL PL18799773.9T patent/PL3510051T5/pl unknown
- 2018-11-09 US US16/767,571 patent/US11667727B2/en active Active
- 2018-11-12 AR ARP180103294A patent/AR115049A1/es active IP Right Grant
-
2020
- 2020-05-19 CL CL2020001323A patent/CL2020001323A1/es unknown
-
2023
- 2023-01-30 US US18/103,132 patent/US20230174682A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| MX2020005002A (es) | 2020-08-27 |
| PL3510051T3 (pl) | 2020-11-02 |
| EP3510051B1 (fr) | 2020-01-01 |
| PT3510051T (pt) | 2020-04-06 |
| HRP20200411T1 (hr) | 2020-06-12 |
| MA49811A1 (fr) | 2020-10-28 |
| TN2020000070A1 (fr) | 2022-01-06 |
| US11667727B2 (en) | 2023-06-06 |
| SG11202005039WA (en) | 2020-06-29 |
| WO2019105719A1 (fr) | 2019-06-06 |
| PL3510051T5 (pl) | 2023-01-30 |
| PE20210441A1 (es) | 2021-03-08 |
| US20210171667A1 (en) | 2021-06-10 |
| EP3510051A1 (fr) | 2019-07-17 |
| CA3082557A1 (fr) | 2019-06-06 |
| FI3510051T4 (en) | 2022-12-15 |
| EP3510051B2 (fr) | 2022-10-05 |
| EA202091062A1 (ru) | 2020-08-07 |
| HRP20200411T4 (hr) | 2022-11-25 |
| ES2781787T3 (es) | 2020-09-07 |
| FR3074044B1 (fr) | 2019-11-01 |
| CL2020001323A1 (es) | 2020-09-11 |
| US20230174682A1 (en) | 2023-06-08 |
| ES2781787T5 (es) | 2023-02-27 |
| FR3074044A1 (fr) | 2019-05-31 |
| DK3510051T3 (da) | 2020-03-16 |
| UA126087C2 (uk) | 2022-08-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant, registration |