AR115030A1 - Membrana bioabsorbible para regeneración de tejidos y procedimiento de preparación - Google Patents

Membrana bioabsorbible para regeneración de tejidos y procedimiento de preparación

Info

Publication number
AR115030A1
AR115030A1 ARP190100898A ARP190100898A AR115030A1 AR 115030 A1 AR115030 A1 AR 115030A1 AR P190100898 A ARP190100898 A AR P190100898A AR P190100898 A ARP190100898 A AR P190100898A AR 115030 A1 AR115030 A1 AR 115030A1
Authority
AR
Argentina
Prior art keywords
membrane
stirring
poly
plga
phbv
Prior art date
Application number
ARP190100898A
Other languages
English (en)
Inventor
Alberto Nazareno Bolgiani
Elida Beatriz Hermida
Arias Ignacio Edgardo Ruiz
Original Assignee
Concejo Nacional De Investigaciones Cientificas Y Tecn Conicet
Univ Nacional De San Martin Unsam
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Concejo Nacional De Investigaciones Cientificas Y Tecn Conicet, Univ Nacional De San Martin Unsam filed Critical Concejo Nacional De Investigaciones Cientificas Y Tecn Conicet
Priority to ARP190100898A priority Critical patent/AR115030A1/es
Priority to PCT/US2020/026312 priority patent/WO2020206067A1/en
Publication of AR115030A1 publication Critical patent/AR115030A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/60—Materials for use in artificial skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/26—Mixtures of macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3641—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the site of application in the body
    • A61L27/3666—Epithelial tissues other than skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A61L27/3813—Epithelial cells, e.g. keratinocytes, urothelial cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56—Porous materials, e.g. foams or sponges
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/58—Materials at least partially resorbable by the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/30—Compounds of undetermined constitution extracted from natural sources, e.g. Aloe Vera
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/80—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special chemical form
    • A61L2300/802—Additives, excipients, e.g. cyclodextrins, fatty acids, surfactants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Botany (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cell Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Zoology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Vascular Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)

Abstract

Membrana bioabsorbible para regeneración de tejido que comprende: poli(3-hidroxibutirato-co-3-hidroxivalerato) (PHBV), polivinilpirrolidona-vinil acetato (PVP) y poli(lactido-co-glicolido) (PLGA). La membrana comprende entre 65 y 80% en peso de poli(3-hidroxibutirato-co-3-hidroxivalerato) (PHBV), entre 4 y 15% en peso de copolímero polivinilpirrolidona-vinil acetato (PVP) y entre 0,5 y 10% en peso de poli(lactido-co-glicolido) (PLGA) y entre 4 y 10 de un surfactante. Reivindicación 9: Un procedimiento para preparar la membrana de la reivindicación 1, caracterizado porque comprende las siguientes etapas: a) disolver PHBV en cloroformo bajo agitación; b) agregar PLGA manteniendo la agitación, hasta disolución del PLGA; c) adicionar PVP manteniendo la agitación; d) cuando los polímeros de las etapas anteriores se han disuelto agregar un surfactante bajo agitación; e) agregar tolueno bajo agitación; f) agregar agua bajo agitación; g) extender la mezcla obtenida en la etapa anterior sobre una superficie; y h) secar le mezcla extendida hasta obtener una membrana de entre 50 y 500 mm de espesor.
ARP190100898A 2019-04-05 2019-04-05 Membrana bioabsorbible para regeneración de tejidos y procedimiento de preparación AR115030A1 (es)

Priority Applications (2)

Application Number Priority Date Filing Date Title
ARP190100898A AR115030A1 (es) 2019-04-05 2019-04-05 Membrana bioabsorbible para regeneración de tejidos y procedimiento de preparación
PCT/US2020/026312 WO2020206067A1 (en) 2019-04-05 2020-04-02 Bioabsorbable membrane for tissue regeneration and process for preparing the same

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ARP190100898A AR115030A1 (es) 2019-04-05 2019-04-05 Membrana bioabsorbible para regeneración de tejidos y procedimiento de preparación

Publications (1)

Publication Number Publication Date
AR115030A1 true AR115030A1 (es) 2020-11-18

Family

ID=72664315

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP190100898A AR115030A1 (es) 2019-04-05 2019-04-05 Membrana bioabsorbible para regeneración de tejidos y procedimiento de preparación

Country Status (2)

Country Link
AR (1) AR115030A1 (es)
WO (1) WO2020206067A1 (es)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6576269B1 (en) * 2001-09-06 2003-06-10 Alexander Y. Korneyev Treating open skin lesions using extract of sea buckthorn
DE60131170T2 (de) * 2001-09-28 2008-03-06 Dainippon Ink And Chemicals, Inc. Künstliche Lunge des Membrantyps
US20040136968A1 (en) * 2002-09-27 2004-07-15 Verigen Ag Autologous cells on a support matrix for tissue repair
US8858986B2 (en) * 2008-06-12 2014-10-14 3M Innovative Properties Company Biocompatible hydrophilic compositions
EP2457598B1 (en) * 2010-11-12 2014-10-08 nolax AG Resorbable membrane
US10632228B2 (en) * 2016-05-12 2020-04-28 Acera Surgical, Inc. Tissue substitute materials and methods for tissue repair

Also Published As

Publication number Publication date
WO2020206067A1 (en) 2020-10-08

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