AR114355A1 - COMPOSITION OF THE PNEUMOCOCCAL MULTIVALENT PROTEIN-POLYSACCHARIDE CONJUGATE - Google Patents
COMPOSITION OF THE PNEUMOCOCCAL MULTIVALENT PROTEIN-POLYSACCHARIDE CONJUGATEInfo
- Publication number
- AR114355A1 AR114355A1 ARP190100274A ARP190100274A AR114355A1 AR 114355 A1 AR114355 A1 AR 114355A1 AR P190100274 A ARP190100274 A AR P190100274A AR P190100274 A ARP190100274 A AR P190100274A AR 114355 A1 AR114355 A1 AR 114355A1
- Authority
- AR
- Argentina
- Prior art keywords
- pneumococcal
- conjugated
- serotypes
- streptococcus pneumoniae
- composition
- Prior art date
Links
Landscapes
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
Abstract
Se proporcionan composiciones conjugadas multivalentes neumocócicas con portador mixto, que comprenden 21 conjugados de proteína-polisacárido capsular neumocócicos diferentes, donde cada uno de los conjugados incluye un polisacárido capsular de un serotipo diferente de Streptococcus pneumoniae conjugado con toxoide tetánico (TT) o CRM₁₉₇, donde los serotipos de Streptococcus pneumoniae se seleccionan entre 1, 3, 4, 5, 6A, 6B, 7F, 8, 9N, 9V, 10A, 11A, 12F, 14, 15B, 18C, 19A, 19F, 22F, 23F y 33F, donde los polisacáridos capsulares de dos de los serotipos de 1, 3, y 5 y uno o ambos de los dos serotipos 15B y 22F están conjugados con TT y los polisacáridos capsulares restantes están conjugados con CRM₁₉₇. También se proporcionan métodos para producir las composiciones conjugadas multivalentes neumocócicas con portador mixto y métodos de uso de estas para la profilaxis frente a una infección o enfermedad por Streptococcus pneumoniae en un sujeto.Mixed carrier pneumococcal multivalent conjugated compositions are provided, comprising 21 different pneumococcal capsular polysaccharide protein-conjugates, where each of the conjugates includes a capsular polysaccharide of a different serotype of Streptococcus pneumoniae conjugated to tetanus toxoid (TT) or CRM₁₉₇, where Streptococcus pneumoniae serotypes are selected from 1, 3, 4, 5, 6A, 6B, 7F, 8, 9N, 9V, 10A, 11A, 12F, 14, 15B, 18C, 19A, 19F, 22F, 23F and 33F, where the capsular polysaccharides of two of the serotypes 1, 3, and 5 and one or both of the two serotypes 15B and 22F are conjugated with TT and the remaining capsular polysaccharides are conjugated with CRM₁₉₇. Also provided are methods of producing the mixed carrier pneumococcal multivalent conjugate compositions and methods of using these for prophylaxis against Streptococcus pneumoniae infection or disease in a subject.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862626509P | 2018-02-05 | 2018-02-05 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR114355A1 true AR114355A1 (en) | 2020-08-26 |
Family
ID=72291202
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP190100274A AR114355A1 (en) | 2018-02-05 | 2019-02-05 | COMPOSITION OF THE PNEUMOCOCCAL MULTIVALENT PROTEIN-POLYSACCHARIDE CONJUGATE |
Country Status (1)
| Country | Link |
|---|---|
| AR (1) | AR114355A1 (en) |
-
2019
- 2019-02-05 AR ARP190100274A patent/AR114355A1/en unknown
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