AR122291A1 - MULTIVALENT PNEUMOCOCCAL POLYSACCHARIDE-PROTEIN CONJUGATE COMPOSITIONS AND METHODS FOR USING THE SAME - Google Patents

MULTIVALENT PNEUMOCOCCAL POLYSACCHARIDE-PROTEIN CONJUGATE COMPOSITIONS AND METHODS FOR USING THE SAME

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Publication number
AR122291A1
AR122291A1 ARP200102173A ARP200102173A AR122291A1 AR 122291 A1 AR122291 A1 AR 122291A1 AR P200102173 A ARP200102173 A AR P200102173A AR P200102173 A ARP200102173 A AR P200102173A AR 122291 A1 AR122291 A1 AR 122291A1
Authority
AR
Argentina
Prior art keywords
methods
same
polysaccharide
streptococcus pneumoniae
protein conjugate
Prior art date
Application number
ARP200102173A
Other languages
Spanish (es)
Inventor
Jinhwan Shin
Sunghyun Kim
Hun Kim
Kyungjun An
Jeong Lee
- Kyaw Moe Min
Philippe Talaga
Original Assignee
Sk Bioscience Co Ltd
Sanofi Pasteur Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sk Bioscience Co Ltd, Sanofi Pasteur Inc filed Critical Sk Bioscience Co Ltd
Publication of AR122291A1 publication Critical patent/AR122291A1/en

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Abstract

Se proporcionan en la presente composiciones conjugadas neumocócicas multivalentes que comprenden 22 - 27 diferentes conjugados neumocócicos polisacárido capsular - proteína, donde cada conjugado polisacárido capsular neumocócico - proteína comprende una proteína portadora conjugada a un polisacárido capsular de un serotipo diferente de Streptococcus pneumoniae, donde los serotipos Streptococcus pneumoniae se seleccionan entre 1, 3, 4, 5, 6A, 6B, 7F, 8, 9N, 9V, 10A, 11A, 12F, 14, 15A, 15B, 15C, 18C, 19A, 19F, 22F, 23A, 23B, 23F, 24F, 33F, y 35B. También se proporciona en la presente los métodos para producir las composiciones conjugadas neumocócicas multivalentes y los métodos para utilizar las mismas para profilaxis contra infección o enfermedad por Streptococcus pneumoniae en un sujeto. También se proporcionan composiciones inmunogénicas que comprenden al menos un conjugado polisacárido - proteína donde el polisacárido es un polisacárido capsular de Streptococcus pneumoniae serotipo 15A, 15C, 23A, 23B, 24F, y/o 35B y métodos para preparar las mismas.Provided herein are multivalent pneumococcal conjugate compositions comprising 22-27 different pneumococcal capsular polysaccharide-protein conjugates, where each pneumococcal capsular polysaccharide-protein conjugate comprises a carrier protein conjugated to a capsular polysaccharide from a different serotype of Streptococcus pneumoniae, where the serotypes Streptococcus pneumoniae are selected from 1, 3, 4, 5, 6A, 6B, 7F, 8, 9N, 9V, 10A, 11A, 12F, 14, 15A, 15B, 15C, 18C, 19A, 19F, 22F, 23A, 23B , 23F, 24F, 33F, and 35B. Also provided herein are methods of producing the multivalent pneumococcal conjugate compositions and methods of using the same for prophylaxis against Streptococcus pneumoniae infection or disease in a subject. Also provided are immunogenic compositions comprising at least one polysaccharide-protein conjugate where the polysaccharide is a capsular polysaccharide from Streptococcus pneumoniae serotype 15A, 15C, 23A, 23B, 24F, and/or 35B, and methods for preparing the same.

ARP200102173A 2019-07-31 2020-07-31 MULTIVALENT PNEUMOCOCCAL POLYSACCHARIDE-PROTEIN CONJUGATE COMPOSITIONS AND METHODS FOR USING THE SAME AR122291A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR20190093276 2019-07-31

Publications (1)

Publication Number Publication Date
AR122291A1 true AR122291A1 (en) 2022-08-31

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ID=83218725

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP200102173A AR122291A1 (en) 2019-07-31 2020-07-31 MULTIVALENT PNEUMOCOCCAL POLYSACCHARIDE-PROTEIN CONJUGATE COMPOSITIONS AND METHODS FOR USING THE SAME

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AR (1) AR122291A1 (en)

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