AR111282A1 - Inhibidores de cdpk1 ii, composiciones y métodos relacionados con los mismos - Google Patents

Inhibidores de cdpk1 ii, composiciones y métodos relacionados con los mismos

Info

Publication number
AR111282A1
AR111282A1 ARP180100606A ARP180100606A AR111282A1 AR 111282 A1 AR111282 A1 AR 111282A1 AR P180100606 A ARP180100606 A AR P180100606A AR P180100606 A ARP180100606 A AR P180100606A AR 111282 A1 AR111282 A1 AR 111282A1
Authority
AR
Argentina
Prior art keywords
cdpk1
inhibitors
compositions
same
methods related
Prior art date
Application number
ARP180100606A
Other languages
English (en)
Original Assignee
Vyera Pharmaceuticals Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vyera Pharmaceuticals Llc filed Critical Vyera Pharmaceuticals Llc
Publication of AR111282A1 publication Critical patent/AR111282A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Reivindicación 1: Un compuesto con la estructura de fórmula (1), o una sal aceptable farmacéutico del mismo, en la que: X es R⁶, O, S, (NR⁴), OR⁶, SR⁶, o (NR⁴)R⁶; Y es N o CH; R¹ es arilo C₆₋₁₀ o heteroarilo de 5 - 10 miembros; R² es cicloalquilo C₃₋₆; R³ es H, alquilo C₁₋₆, haloalquilo C₁₋₆, cicloalquilo C₃₋₆; R⁴ es H o alquilo C₁₋₆; y R⁶ es alquileno C₁₋₆ o alquenileno C₁₋₆.
ARP180100606A 2017-03-15 2018-03-15 Inhibidores de cdpk1 ii, composiciones y métodos relacionados con los mismos AR111282A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201762471795P 2017-03-15 2017-03-15

Publications (1)

Publication Number Publication Date
AR111282A1 true AR111282A1 (es) 2019-06-26

Family

ID=63522614

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP180100606A AR111282A1 (es) 2017-03-15 2018-03-15 Inhibidores de cdpk1 ii, composiciones y métodos relacionados con los mismos

Country Status (5)

Country Link
US (1) US20210115047A1 (es)
EP (1) EP3596082A4 (es)
AR (1) AR111282A1 (es)
TW (1) TW201837040A (es)
WO (1) WO2018170236A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW201920184A (zh) * 2017-08-17 2019-06-01 美國華盛頓大學 Cdpk1抑制劑、組合物及與其相關之方法
MA53672A (fr) * 2018-09-19 2021-07-28 Vyera Pharmaceuticals Llc Inhibiteurs de cdpk1, compositions et procédés associés
CN111592557A (zh) * 2020-05-09 2020-08-28 河北合佳医药科技集团股份有限公司 一种7-氨基-3-乙烯基头孢烷酸的一步法环保制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9512125B2 (en) * 2004-11-19 2016-12-06 The Regents Of The University Of California Substituted pyrazolo[3.4-D] pyrimidines as anti-inflammatory agents
EA201070572A1 (ru) * 2007-11-07 2010-12-30 Фолдркс Фармасьютикалз, Инк. Модуляция транспорта белков
ES2570429T3 (es) * 2008-10-16 2016-05-18 Univ California Inhibidores de heteroaril quinasa de anillo condensado
US9765037B2 (en) * 2010-01-28 2017-09-19 University Of Washington Through Its Center For Commercialization Compositions and methods for treating toxoplasmosis, cryptosporidiosis, and other apicomplexan protozoan related diseases
WO2011153553A2 (en) * 2010-06-04 2011-12-08 The Regents Of The University Of California Methods and compositions for kinase inhibition
US8642606B2 (en) * 2010-09-29 2014-02-04 Plexxikon Inc. ZAP-70 active compounds
AU2012283775A1 (en) * 2011-07-13 2014-01-23 Pharmacyclics Llc Inhibitors of Bruton's tyrosine kinase

Also Published As

Publication number Publication date
WO2018170236A9 (en) 2019-01-17
US20210115047A1 (en) 2021-04-22
EP3596082A4 (en) 2020-12-16
TW201837040A (zh) 2018-10-16
WO2018170236A1 (en) 2018-09-20
EP3596082A1 (en) 2020-01-22

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