AR111224A1 - PROCESSES FOR THE PREPARATION OF FUNGICIDE COMPOUNDS OF TIENOPIRIMIDINE - Google Patents

PROCESSES FOR THE PREPARATION OF FUNGICIDE COMPOUNDS OF TIENOPIRIMIDINE

Info

Publication number
AR111224A1
AR111224A1 ARP180100490A ARP180100490A AR111224A1 AR 111224 A1 AR111224 A1 AR 111224A1 AR P180100490 A ARP180100490 A AR P180100490A AR P180100490 A ARP180100490 A AR P180100490A AR 111224 A1 AR111224 A1 AR 111224A1
Authority
AR
Argentina
Prior art keywords
salt
formula
tienopirimidine
processes
preparation
Prior art date
Application number
ARP180100490A
Other languages
Spanish (es)
Inventor
Geraldine C Harriman
Shomir Ghosh
Jon Lawson
Matthew W Leighty
De Moradei Silvana Marcel Leit
William H Miller
Toni Poel
- Schostarez Heinrich J Jo
Lloyd J Simons
Urszula J Slomczynska
Daniel P Walker
Original Assignee
Gilead Apollo Llc
Monsanto Technology Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gilead Apollo Llc, Monsanto Technology Llc filed Critical Gilead Apollo Llc
Publication of AR111224A1 publication Critical patent/AR111224A1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B6/00Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings
    • G02B6/24Coupling light guides
    • G02B6/36Mechanical coupling means
    • G02B6/38Mechanical coupling means having fibre to fibre mating means
    • G02B6/3807Dismountable connectors, i.e. comprising plugs
    • G02B6/389Dismountable connectors, i.e. comprising plugs characterised by the method of fastening connecting plugs and sockets, e.g. screw- or nut-lock, snap-in, bayonet type
    • G02B6/3893Push-pull type, e.g. snap-in, push-on
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B6/00Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings
    • G02B6/24Coupling light guides
    • G02B6/36Mechanical coupling means
    • G02B6/38Mechanical coupling means having fibre to fibre mating means
    • G02B6/3807Dismountable connectors, i.e. comprising plugs
    • G02B6/3897Connectors fixed to housings, casing, frames or circuit boards
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B6/00Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings
    • G02B6/44Mechanical structures for providing tensile strength and external protection for fibres, e.g. optical transmission cables
    • G02B6/4439Auxiliary devices
    • G02B6/444Systems or boxes with surplus lengths
    • G02B6/4453Cassettes
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B6/00Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings
    • G02B6/44Mechanical structures for providing tensile strength and external protection for fibres, e.g. optical transmission cables
    • G02B6/4439Auxiliary devices
    • G02B6/4471Terminating devices ; Cable clamps

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Plant Pathology (AREA)
  • Health & Medical Sciences (AREA)
  • Agronomy & Crop Science (AREA)
  • Dentistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pest Control & Pesticides (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

Los compuestos descriptos en este documento exhiben actividad como pesticidas y son útiles, por ejemplo, en métodos para el control de patógenos fúngicos y enfermedades causadas por patógenos fúngicos en plantas. Reivindicación 1: Un proceso para preparar un compuesto estereoméricamente enriquecido de fórmula (1) ó (2), o una sal del mismo, comprendiendo el proceso el contacto de un compuesto de fórmula (3) ó (4), o una sal del mismo, con una fuente de hidrógeno en presencia de un catalizador organometálico quiral en una zona de reducción asimétrica que comprende un medio de reacción, proporcionando de ese modo el compuesto o sal enriquecido estereoméricamente de fórmula (1) ó (2), respectivamente; donde: R¹ es 2H-1,2,3-triazol-2-ilo, 1-pirazolilo o -C(O)OCH₂CH₃; y R² es hidrógeno o F.The compounds described in this document exhibit activity as pesticides and are useful, for example, in methods for the control of fungal pathogens and diseases caused by fungal pathogens in plants. Claim 1: A process for preparing a stereomerically enriched compound of formula (1) or (2), or a salt thereof, the process comprising contacting a compound of formula (3) or (4), or a salt thereof , with a source of hydrogen in the presence of a chiral organometallic catalyst in an asymmetric reduction zone comprising a reaction medium, thereby providing the stereomerically enriched compound or salt of formula (1) or (2), respectively; where: R¹ is 2H-1,2,3-triazol-2-yl, 1-pyrazolyl or -C (O) OCH₂CH₃; and R² is hydrogen or F.

ARP180100490A 2017-03-03 2018-03-02 PROCESSES FOR THE PREPARATION OF FUNGICIDE COMPOUNDS OF TIENOPIRIMIDINE AR111224A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201762466944P 2017-03-03 2017-03-03

Publications (1)

Publication Number Publication Date
AR111224A1 true AR111224A1 (en) 2019-06-19

Family

ID=61683933

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP180100490A AR111224A1 (en) 2017-03-03 2018-03-02 PROCESSES FOR THE PREPARATION OF FUNGICIDE COMPOUNDS OF TIENOPIRIMIDINE

Country Status (11)

Country Link
EP (1) EP3589635A1 (en)
JP (1) JP2020509038A (en)
KR (1) KR20190125359A (en)
CN (1) CN110382504A (en)
AR (1) AR111224A1 (en)
AU (1) AU2018227575A1 (en)
BR (1) BR112019017915A2 (en)
CA (1) CA3054810A1 (en)
CO (1) CO2019009579A2 (en)
EA (1) EA201991880A1 (en)
WO (1) WO2018161008A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2018227588B2 (en) 2017-03-03 2021-01-21 Gilead Sciences, Inc. Processes for preparing ACC inhibitors and solid forms thereof
WO2020092239A1 (en) * 2018-10-29 2020-05-07 Gilead Apollo, Llc Processes for the preparation of fungicidal compounds
EP3669652A1 (en) 2018-12-21 2020-06-24 Bayer AG Active compound combination
AR119594A1 (en) 2019-08-09 2021-12-29 Gilead Sciences Inc THIENOPYRIMIDINE DERIVATIVES AS ACC INHIBITORS AND USES THEREOF
WO2021149771A1 (en) * 2020-01-22 2021-07-29 日産化学株式会社 Thienouracil compound and pest control agent
CN114539042A (en) * 2022-02-23 2022-05-27 河南旭瑞新材料科技有限公司 Novel synthesis process of 5-fluoro-2-hydroxyacetophenone

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX370976B (en) * 2011-11-11 2020-01-10 Gilead Apollo Llc Acc inhibitors and uses thereof.
AR106472A1 (en) * 2015-10-26 2018-01-17 Gilead Apollo Llc ACC INHIBITORS AND USES OF THE SAME
SI3380480T1 (en) * 2015-11-25 2023-04-28 Gilead Apollo, Llc Pyrazole acc inhibitors and uses thereof
WO2017091602A1 (en) * 2015-11-25 2017-06-01 Gilead Apollo, Llc Ester acc inhibitors and uses thereof
JP2019503338A (en) * 2015-11-25 2019-02-07 ギリアド アポロ, エルエルシー Fungicidal composition comprising a derivative of 2,4-dioxo-1,4-dihydrothieno [2,3-d] pyrimidine
JP2018536661A (en) 2015-11-25 2018-12-13 ギリアド アポロ, エルエルシー Triazole ACC inhibitors and uses thereof

Also Published As

Publication number Publication date
WO2018161008A1 (en) 2018-09-07
EP3589635A1 (en) 2020-01-08
KR20190125359A (en) 2019-11-06
CO2019009579A2 (en) 2020-01-17
JP2020509038A (en) 2020-03-26
CA3054810A1 (en) 2018-09-07
EA201991880A1 (en) 2020-02-25
BR112019017915A2 (en) 2020-05-12
CN110382504A (en) 2019-10-25
AU2018227575A1 (en) 2019-09-19

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