AR108552A1 - Materiales y métodos para determinar los regímenes óptimos de administración para agentes terapéuticos - Google Patents
Materiales y métodos para determinar los regímenes óptimos de administración para agentes terapéuticosInfo
- Publication number
- AR108552A1 AR108552A1 ARP170101381A ARP170101381A AR108552A1 AR 108552 A1 AR108552 A1 AR 108552A1 AR P170101381 A ARP170101381 A AR P170101381A AR P170101381 A ARP170101381 A AR P170101381A AR 108552 A1 AR108552 A1 AR 108552A1
- Authority
- AR
- Argentina
- Prior art keywords
- therapeutic agent
- value
- cells
- rate
- il2r
- Prior art date
Links
- 239000003814 drug Substances 0.000 title abstract 18
- 229940124597 therapeutic agent Drugs 0.000 title abstract 18
- 238000000034 method Methods 0.000 title abstract 4
- 239000000463 material Substances 0.000 title 1
- 101001055144 Homo sapiens Interleukin-2 receptor subunit alpha Proteins 0.000 abstract 6
- 102100026878 Interleukin-2 receptor subunit alpha Human genes 0.000 abstract 6
- 210000004027 cell Anatomy 0.000 abstract 6
- 108010038453 Interleukin-2 Receptors Proteins 0.000 abstract 5
- 102000010789 Interleukin-2 Receptors Human genes 0.000 abstract 5
- 102000000588 Interleukin-2 Human genes 0.000 abstract 2
- 108010002350 Interleukin-2 Proteins 0.000 abstract 2
- 210000002865 immune cell Anatomy 0.000 abstract 2
- 230000001900 immune effect Effects 0.000 abstract 2
- 108040006849 interleukin-2 receptor activity proteins Proteins 0.000 abstract 2
- 239000008280 blood Substances 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000000354 decomposition reaction Methods 0.000 abstract 1
- 238000010494 dissociation reaction Methods 0.000 abstract 1
- 230000005593 dissociations Effects 0.000 abstract 1
- 230000008030 elimination Effects 0.000 abstract 1
- 238000003379 elimination reaction Methods 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H20/00—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
- G16H20/10—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16C—COMPUTATIONAL CHEMISTRY; CHEMOINFORMATICS; COMPUTATIONAL MATERIALS SCIENCE
- G16C20/00—Chemoinformatics, i.e. ICT specially adapted for the handling of physicochemical or structural data of chemical particles, elements, compounds or mixtures
- G16C20/50—Molecular design, e.g. of drugs
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H10/00—ICT specially adapted for the handling or processing of patient-related medical or healthcare data
- G16H10/40—ICT specially adapted for the handling or processing of patient-related medical or healthcare data for data related to laboratory analysis, e.g. patient specimen analysis
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
- G16H50/50—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for simulation or modelling of medical disorders
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medical Informatics (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Primary Health Care (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Pathology (AREA)
- Databases & Information Systems (AREA)
- Data Mining & Analysis (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Theoretical Computer Science (AREA)
- Computing Systems (AREA)
- Bioinformatics & Computational Biology (AREA)
- Physics & Mathematics (AREA)
- Hematology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Oncology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Biochemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Urology & Nephrology (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16171263 | 2016-05-25 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR108552A1 true AR108552A1 (es) | 2018-08-29 |
Family
ID=56096950
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP170101381A AR108552A1 (es) | 2016-05-25 | 2017-05-23 | Materiales y métodos para determinar los regímenes óptimos de administración para agentes terapéuticos |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20190361018A1 (ko) |
| EP (1) | EP3465494A1 (ko) |
| JP (1) | JP6943885B2 (ko) |
| KR (1) | KR20190015345A (ko) |
| CN (1) | CN109478421B (ko) |
| AR (1) | AR108552A1 (ko) |
| AU (1) | AU2017269764A1 (ko) |
| BR (1) | BR112018074152A8 (ko) |
| CA (1) | CA3025050A1 (ko) |
| IL (1) | IL263073A (ko) |
| MX (1) | MX2018014432A (ko) |
| WO (1) | WO2017202786A1 (ko) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3056630A1 (en) | 2017-03-15 | 2018-09-20 | Pandion Therapeutics, Inc. | Targeted immunotolerance |
| CN111010866A (zh) | 2017-05-24 | 2020-04-14 | 潘迪恩治疗公司 | 靶向免疫耐受性 |
| US10174091B1 (en) | 2017-12-06 | 2019-01-08 | Pandion Therapeutics, Inc. | IL-2 muteins |
| US10946068B2 (en) | 2017-12-06 | 2021-03-16 | Pandion Operations, Inc. | IL-2 muteins and uses thereof |
| AU2020279240A1 (en) | 2019-05-20 | 2021-12-23 | Pandion Operations, Inc. | MAdCAM targeted immunotolerance |
| EP4048302A1 (en) * | 2019-10-25 | 2022-08-31 | Neoleukin Therapeutics, Inc. | Methods of administration of il-2 receptor agonists |
| US11981715B2 (en) | 2020-02-21 | 2024-05-14 | Pandion Operations, Inc. | Tissue targeted immunotolerance with a CD39 effector |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10245508A1 (de) * | 2002-09-27 | 2004-04-08 | Mcs Micro Carrier Systems Gmbh | Medikament-Dosimeter-Kombipackung |
| US20090123428A1 (en) * | 2003-04-21 | 2009-05-14 | Hall Frederick L | Pathotropic targeted gene delivery system for cancer and other disorders |
| US20070098685A1 (en) * | 2005-01-19 | 2007-05-03 | Brand Stephen J | Methods and kits to treat chronic inflammatory immune diseases by administering a proteasome inhibitor and an interleukin 2 receptor agonist |
| JP2009517186A (ja) * | 2005-11-29 | 2009-04-30 | チルドレンズ ホスピタル メディカル センター | 薬物選択及び投薬の最適化及び個別化 |
| DE102006028232A1 (de) * | 2006-06-20 | 2007-12-27 | Bayer Technology Services Gmbh | Vorrichtung und Verfahren zur Berechnung und Bereitstellung einer Medikamentendosis |
| ES2967617T3 (es) * | 2013-12-06 | 2024-05-03 | Bioverativ Therapeutics Inc | Herramientas de farmacocinética poblacional y sus usos |
| EP3193915A1 (en) * | 2014-07-21 | 2017-07-26 | Novartis AG | Combinations of low, immune enhancing. doses of mtor inhibitors and cars |
| WO2016025385A1 (en) * | 2014-08-11 | 2016-02-18 | Delinia, Inc. | Modified il-2 variants that selectively activate regulatory t cells for the treatment of autoimmune diseases |
-
2017
- 2017-05-22 CN CN201780045896.7A patent/CN109478421B/zh active Active
- 2017-05-22 AU AU2017269764A patent/AU2017269764A1/en not_active Abandoned
- 2017-05-22 BR BR112018074152A patent/BR112018074152A8/pt not_active IP Right Cessation
- 2017-05-22 JP JP2018561513A patent/JP6943885B2/ja active Active
- 2017-05-22 MX MX2018014432A patent/MX2018014432A/es unknown
- 2017-05-22 WO PCT/EP2017/062302 patent/WO2017202786A1/en unknown
- 2017-05-22 EP EP17727144.2A patent/EP3465494A1/en active Pending
- 2017-05-22 CA CA3025050A patent/CA3025050A1/en not_active Abandoned
- 2017-05-22 KR KR1020187037309A patent/KR20190015345A/ko active IP Right Grant
- 2017-05-23 AR ARP170101381A patent/AR108552A1/es unknown
-
2018
- 2018-11-18 IL IL263073A patent/IL263073A/en unknown
- 2018-11-20 US US16/196,883 patent/US20190361018A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CA3025050A1 (en) | 2017-11-30 |
| JP2019530907A (ja) | 2019-10-24 |
| US20190361018A1 (en) | 2019-11-28 |
| IL263073A (en) | 2019-03-31 |
| AU2017269764A1 (en) | 2018-12-13 |
| EP3465494A1 (en) | 2019-04-10 |
| CN109478421B (zh) | 2024-07-09 |
| JP6943885B2 (ja) | 2021-10-06 |
| BR112018074152A8 (pt) | 2023-01-31 |
| WO2017202786A1 (en) | 2017-11-30 |
| CN109478421A (zh) | 2019-03-15 |
| BR112018074152A2 (pt) | 2019-03-06 |
| MX2018014432A (es) | 2019-04-01 |
| KR20190015345A (ko) | 2019-02-13 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AR108552A1 (es) | Materiales y métodos para determinar los regímenes óptimos de administración para agentes terapéuticos | |
| CO2019010698A2 (es) | Vacunas de peptidos | |
| CL2018002763A1 (es) | Moléculas de unión a bcma y métodos de uso de las mismas. | |
| MX2019005125A (es) | Variantes de superficie celular discernibles inmunologicamente para uso en terapia celular. | |
| SA522431672B1 (ar) | Cd3 أجسام مضادة للارتباط بـ | |
| MX2019008413A (es) | Celulas pluripotentes inmunodiseñadas. | |
| CY1122155T1 (el) | Συζευγμενες ενωσεις που περιλαμβανουν αντισωματα τροποποιημενης κυστεϊνης | |
| EA202190295A1 (ru) | Т-клетки с химерным антигенным рецептором, происходящие от плюрипотентных стволовых клеток, полученных посредством иммуноинженерии | |
| PH12018502250A1 (en) | Cancer immunotherapy by immune activation for immune modulation via globo series antigens | |
| AR109707A1 (es) | Generación y uso en inmunoterapia adoptiva de células t de memoria tipo células madre | |
| MX2020006715A (es) | Anticuerpos especificos del heterodimero de cd3-delta/epsilon. | |
| WO2020113194A3 (en) | Methods for treatment using adoptive cell therapy | |
| BR112017014551A2 (pt) | ?anticorpo, construção de ácido nucleico, vetor de expressão, célula hospedeira, composição, métodos para tratamento de uma doença, para produção de um anticorpo biespecífico e para detecção da possível ocorrência de reticulação entre células com expressão de cd3 e cd20 em uma amostra derivada de um paciente, uso de um anticorpo biespecífico, e, kit? | |
| MX2019004692A (es) | Anticuerpos 4-1bb anti-humano y usos de los mismos. | |
| MX2019015155A (es) | Modelo de raton para valorar toxicidades asociadas con inmunoterapias. | |
| ECSP21052194A (es) | Tratamiento agudo y tratamiento rápido de la cefalea usando anticuerpos anti-cgrp | |
| WO2008094178A3 (en) | Models for vaccine assessment | |
| AR104296A1 (es) | Infusión arterial hepática de células car-t | |
| WO2014008206A3 (en) | DIAGNOSTIC AND THERAPEUTIC POTENTIAL OF HLA-E MONOSPECIFIC MONOCLONAL IgG ANTIBODIES DIRECTED AGAINST TUMOR CELL SURFACE AND SOLUBLE HLA-E | |
| EA201290759A1 (ru) | Антитела | |
| MX2021006393A (es) | Metodos para expansion ex vivo de celulas exterminadoras naturales y uso de las mismas. | |
| AR066306A1 (es) | Conjunto de partes para el tratamiento del cancer o enfermedades infecciosas. composicion farmaceutica- usos | |
| CR20220329A (es) | Anticuerpos anti–mertk y metodos de uso de los mismos | |
| AR084263A1 (es) | Anticuerpo dirigido contra una proteina de membrana de celulas dendriticas (bdca-2) (blood dendritic cell antigen) | |
| MX2020008730A (es) | Regímenes de dosificación de anticuerpo b7-h4. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |