AR108233A1 - Composiciones farmacéuticas orales de nicotinamida - Google Patents
Composiciones farmacéuticas orales de nicotinamidaInfo
- Publication number
- AR108233A1 AR108233A1 ARP170100995A ARP170100995A AR108233A1 AR 108233 A1 AR108233 A1 AR 108233A1 AR P170100995 A ARP170100995 A AR P170100995A AR P170100995 A ARP170100995 A AR P170100995A AR 108233 A1 AR108233 A1 AR 108233A1
- Authority
- AR
- Argentina
- Prior art keywords
- nicotinamide
- pharmaceutical compositions
- oric
- mesalazine
- delayed
- Prior art date
Links
- DFPAKSUCGFBDDF-UHFFFAOYSA-N Nicotinamide Chemical group NC(=O)C1=CC=CN=C1 DFPAKSUCGFBDDF-UHFFFAOYSA-N 0.000 title abstract 8
- 229960003966 nicotinamide Drugs 0.000 title abstract 4
- 235000005152 nicotinamide Nutrition 0.000 title abstract 4
- 239000011570 nicotinamide Substances 0.000 title abstract 4
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 3
- KBOPZPXVLCULAV-UHFFFAOYSA-N mesalamine Chemical compound NC1=CC=C(O)C(C(O)=O)=C1 KBOPZPXVLCULAV-UHFFFAOYSA-N 0.000 abstract 2
- 229960004963 mesalazine Drugs 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- DFPAKSUCGFBDDF-ZQBYOMGUSA-N [14c]-nicotinamide Chemical compound N[14C](=O)C1=CC=CN=C1 DFPAKSUCGFBDDF-ZQBYOMGUSA-N 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 239000012729 immediate-release (IR) formulation Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/60—Salicylic acid; Derivatives thereof
- A61K31/606—Salicylic acid; Derivatives thereof having amino groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Pain & Pain Management (AREA)
- Nutrition Science (AREA)
- Rheumatology (AREA)
- Physiology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662324415P | 2016-04-19 | 2016-04-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR108233A1 true AR108233A1 (es) | 2018-08-01 |
Family
ID=59227843
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP170100995A AR108233A1 (es) | 2016-04-19 | 2017-04-18 | Composiciones farmacéuticas orales de nicotinamida |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US11622938B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP3445360B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP7021108B2 (cg-RX-API-DMAC7.html) |
| KR (1) | KR20180135020A (cg-RX-API-DMAC7.html) |
| CN (1) | CN109152772B (cg-RX-API-DMAC7.html) |
| AR (1) | AR108233A1 (cg-RX-API-DMAC7.html) |
| AU (1) | AU2017252407A1 (cg-RX-API-DMAC7.html) |
| BR (1) | BR112018071363A2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA3021066C (cg-RX-API-DMAC7.html) |
| ES (1) | ES2848575T3 (cg-RX-API-DMAC7.html) |
| RU (1) | RU2738114C2 (cg-RX-API-DMAC7.html) |
| TW (1) | TW201739455A (cg-RX-API-DMAC7.html) |
| WO (1) | WO2017184563A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG11201408251SA (en) | 2012-06-15 | 2015-01-29 | Conaris Res Inst Ag | A pharmaceutical composition containing nicotinic acid and/or nicotinamide and/or tryptophan for positively influencing the intestinal microbiota |
| CN105813644B (zh) | 2013-12-13 | 2020-07-10 | 康纳里斯研究院股份公司 | 用于有益地影响肠道微生物丛和/或治疗胃肠道炎症的药物组合物 |
| ES2788866T3 (es) | 2013-12-13 | 2020-10-23 | Conaris Res Institute Ag | Una composición farmacéutica que contiene ácido nicotínico y/o nicotinamida para su uso en influir beneficiosamente en los niveles de lípidos en sangre mediante la modificación de la microbiota intestinal |
| US20210236519A1 (en) * | 2020-01-30 | 2021-08-05 | Atoz Pharmaceuticals Pvt Ltd | Controlled release dosage forms of 5-aminosalicylic acid and process thereof |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE791458A (fr) | 1972-07-31 | 1973-05-16 | Merck & Co Inc | Produit microencapsule |
| IT1246382B (it) | 1990-04-17 | 1994-11-18 | Eurand Int | Metodo per la cessione mirata e controllata di farmaci nell'intestino e particolarmente nel colon |
| BR9408581A (pt) | 1994-06-02 | 1997-08-26 | Dan Riga | Medicamento anti-tens o anti-incapacitação e anti-envelhecimento e processo para a sua produção |
| CA2271569C (en) | 1996-11-15 | 2003-01-28 | Gary Lee Manring | Pharmaceutical dosage form with multiple enteric polymer coatings for colonic delivery |
| US6458383B2 (en) | 1999-08-17 | 2002-10-01 | Lipocine, Inc. | Pharmaceutical dosage form for oral administration of hydrophilic drugs, particularly low molecular weight heparin |
| GB0007419D0 (en) | 2000-03-27 | 2000-05-17 | Smithkline Beecham Gmbh | Composition |
| IT1318625B1 (it) | 2000-07-14 | 2003-08-27 | Roberto Valducci | Formulazioni farmaceutiche solide orali a rilascio multifasicoph-dipendente. |
| EP1248599B1 (de) * | 2001-01-31 | 2007-12-05 | Evonik Röhm GmbH | Multipartikuläre arzneiform, enthaltend mindestens zwei unterschiedlich überzogene pelletformen |
| US8048924B2 (en) | 2001-08-29 | 2011-11-01 | Biocon Limited | Methods and compositions employing 4-aminophenylacetic acid compounds |
| US20040185097A1 (en) | 2003-01-31 | 2004-09-23 | Glenmark Pharmaceuticals Ltd. | Controlled release modifying complex and pharmaceutical compositions thereof |
| AU2006206423A1 (en) * | 2005-01-21 | 2006-07-27 | Pharmanova Inc. | Pharmaceutical formulations and methods of use |
| EP1935422A1 (en) | 2006-12-20 | 2008-06-25 | PEJO Iserlohn Heilmittel-und Diät-GmbH & Co.KG | Pharmaceutical composition comprising nicotinamide or nicotinic acid |
| US20080286344A1 (en) | 2007-05-16 | 2008-11-20 | Olivia Darmuzey | Solid form |
| EP2276491A4 (en) | 2008-04-25 | 2011-08-17 | Karolinska Inst Innovations Ab | NEW THERAPY FOR THE TREATMENT OF IRRITATION SYNDROME |
| WO2010010579A1 (en) | 2008-07-19 | 2010-01-28 | Lupin Limited | Multiple unit dosage form of niacin |
| WO2010077908A1 (en) | 2008-12-17 | 2010-07-08 | Altheus Therapeutics, Inc. | Oral formulations |
| US20100159001A1 (en) * | 2008-12-19 | 2010-06-24 | Cardinal John R | Extended-Release Pharmaceutical Formulations |
| GB201003734D0 (en) | 2010-03-05 | 2010-04-21 | Univ Strathclyde | Delayed prolonged drug delivery |
| GB201003731D0 (en) | 2010-03-05 | 2010-04-21 | Univ Strathclyde | Immediate/delayed drug delivery |
| EP2468264A1 (en) | 2010-12-27 | 2012-06-27 | Laboratorios Liconsa, S.A. | Oral pharmaceutical tablet for controled release of mesalazine and process for obtaining it |
| EP2822542A1 (en) | 2012-03-07 | 2015-01-14 | Santarus, Inc. | Controlled-release solid dosage forms of mesalamine |
| US20150164920A1 (en) | 2012-03-30 | 2015-06-18 | Laboratorios Del Dr. Esteve S.A. | Controlled release formulation comprising mesalamine |
| SG11201408251SA (en) * | 2012-06-15 | 2015-01-29 | Conaris Res Inst Ag | A pharmaceutical composition containing nicotinic acid and/or nicotinamide and/or tryptophan for positively influencing the intestinal microbiota |
| US20140178468A1 (en) | 2012-12-24 | 2014-06-26 | Ranbaxy Laboratories Limited | Multiparticulate extended-release composition of mesalamine |
| JP6294457B2 (ja) | 2013-03-15 | 2018-03-14 | ワーナー チルコット カンパニー， エルエルシーＷａｒｎｅｒ Ｃｈｉｌｃｏｔｔ Ｃｏｍｐａｎｙ， Ｌｌｃ | 低減した送達変動性のための複数の投薬要素を備えるメサラミン医薬組成物 |
| ES2785399T3 (es) | 2013-06-14 | 2020-10-06 | Conaris Res Institute Ag | Formulación de nicotinamida de liberación prolongada |
| CN105813644B (zh) * | 2013-12-13 | 2020-07-10 | 康纳里斯研究院股份公司 | 用于有益地影响肠道微生物丛和/或治疗胃肠道炎症的药物组合物 |
| ES2788866T3 (es) | 2013-12-13 | 2020-10-23 | Conaris Res Institute Ag | Una composición farmacéutica que contiene ácido nicotínico y/o nicotinamida para su uso en influir beneficiosamente en los niveles de lípidos en sangre mediante la modificación de la microbiota intestinal |
| US20170143743A1 (en) * | 2014-06-16 | 2017-05-25 | Valpharma International S.P.A. | Formulation for oral administration containing mesalazine |
| US20160045442A1 (en) | 2014-08-13 | 2016-02-18 | Cadila Healthcare Limited | Stable pharmaceutical compositions of mesalamine |
| CN104257669A (zh) | 2014-09-25 | 2015-01-07 | 合肥平光制药有限公司 | 一种用于向肠道递送水杨酸类药物的口服给药组合物 |
| KR102381586B1 (ko) | 2016-04-19 | 2022-04-04 | 훼링 비.브이. | 메살라진의 경구용 약제학적 조성물 |
-
2017
- 2017-04-18 ES ES17733604T patent/ES2848575T3/es active Active
- 2017-04-18 JP JP2018554492A patent/JP7021108B2/ja active Active
- 2017-04-18 WO PCT/US2017/028063 patent/WO2017184563A1/en not_active Ceased
- 2017-04-18 AU AU2017252407A patent/AU2017252407A1/en not_active Abandoned
- 2017-04-18 CA CA3021066A patent/CA3021066C/en active Active
- 2017-04-18 EP EP17733604.7A patent/EP3445360B1/en active Active
- 2017-04-18 RU RU2018137323A patent/RU2738114C2/ru active
- 2017-04-18 US US16/094,654 patent/US11622938B2/en active Active
- 2017-04-18 TW TW106112905A patent/TW201739455A/zh unknown
- 2017-04-18 BR BR112018071363A patent/BR112018071363A2/pt not_active Application Discontinuation
- 2017-04-18 CN CN201780029815.4A patent/CN109152772B/zh active Active
- 2017-04-18 AR ARP170100995A patent/AR108233A1/es unknown
- 2017-04-18 KR KR1020187033390A patent/KR20180135020A/ko not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| RU2018137323A (ru) | 2020-05-19 |
| EP3445360A1 (en) | 2019-02-27 |
| EP3445360B1 (en) | 2020-11-11 |
| ES2848575T3 (es) | 2021-08-10 |
| JP7021108B2 (ja) | 2022-02-16 |
| CA3021066C (en) | 2024-04-09 |
| JP2019513801A (ja) | 2019-05-30 |
| TW201739455A (zh) | 2017-11-16 |
| CN109152772B (zh) | 2021-09-28 |
| RU2018137323A3 (cg-RX-API-DMAC7.html) | 2020-07-13 |
| CA3021066A1 (en) | 2017-10-26 |
| US11622938B2 (en) | 2023-04-11 |
| BR112018071363A2 (pt) | 2019-02-05 |
| KR20180135020A (ko) | 2018-12-19 |
| WO2017184563A1 (en) | 2017-10-26 |
| CN109152772A (zh) | 2019-01-04 |
| AU2017252407A1 (en) | 2018-11-01 |
| RU2738114C2 (ru) | 2020-12-08 |
| US20200155461A1 (en) | 2020-05-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |