AR105427A1 - Métodos para la modulación de cinasas - Google Patents
Métodos para la modulación de cinasasInfo
- Publication number
- AR105427A1 AR105427A1 ARP160102208A ARP160102208A AR105427A1 AR 105427 A1 AR105427 A1 AR 105427A1 AR P160102208 A ARP160102208 A AR P160102208A AR P160102208 A ARP160102208 A AR P160102208A AR 105427 A1 AR105427 A1 AR 105427A1
- Authority
- AR
- Argentina
- Prior art keywords
- kinase
- signaling
- nutritional composition
- kinases
- modulation
- Prior art date
Links
- 108091000080 Phosphotransferase Proteins 0.000 title abstract 4
- 102000020233 phosphotransferase Human genes 0.000 title abstract 4
- 230000011664 signaling Effects 0.000 abstract 3
- 102000009516 Protein Serine-Threonine Kinases Human genes 0.000 abstract 2
- 108010009341 Protein Serine-Threonine Kinases Proteins 0.000 abstract 2
- 239000005018 casein Substances 0.000 abstract 2
- BECPQYXYKAMYBN-UHFFFAOYSA-N casein, tech. Chemical compound NCCCCC(C(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(CC(C)C)N=C(O)C(CCC(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(C(C)O)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(COP(O)(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(N)CC1=CC=CC=C1 BECPQYXYKAMYBN-UHFFFAOYSA-N 0.000 abstract 2
- 235000021240 caseins Nutrition 0.000 abstract 2
- 235000016709 nutrition Nutrition 0.000 abstract 2
- MTCFGRXMJLQNBG-REOHCLBHSA-N (2S)-2-Amino-3-hydroxypropansäure Chemical compound OC[C@H](N)C(O)=O MTCFGRXMJLQNBG-REOHCLBHSA-N 0.000 abstract 1
- AYFVYJQAPQTCCC-GBXIJSLDSA-N L-threonine Chemical compound C[C@@H](O)[C@H](N)C(O)=O AYFVYJQAPQTCCC-GBXIJSLDSA-N 0.000 abstract 1
- 102000004022 Protein-Tyrosine Kinases Human genes 0.000 abstract 1
- 108090000412 Protein-Tyrosine Kinases Proteins 0.000 abstract 1
- MTCFGRXMJLQNBG-UHFFFAOYSA-N Serine Natural products OCC(N)C(O)=O MTCFGRXMJLQNBG-UHFFFAOYSA-N 0.000 abstract 1
- AYFVYJQAPQTCCC-UHFFFAOYSA-N Threonine Natural products CC(O)C(N)C(O)=O AYFVYJQAPQTCCC-UHFFFAOYSA-N 0.000 abstract 1
- 239000004473 Threonine Substances 0.000 abstract 1
- 230000022131 cell cycle Effects 0.000 abstract 1
- 239000003102 growth factor Substances 0.000 abstract 1
- 230000006058 immune tolerance Effects 0.000 abstract 1
- 230000002757 inflammatory effect Effects 0.000 abstract 1
- 230000002503 metabolic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/01—Hydrolysed proteins; Derivatives thereof
- A61K38/012—Hydrolysed proteins; Derivatives thereof from animals
- A61K38/018—Hydrolysed proteins; Derivatives thereof from animals from milk
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/18—Peptides; Protein hydrolysates
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/19—Dairy proteins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/40—Complete food formulations for specific consumer groups or specific purposes, e.g. infant formula
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/702—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/716—Glucans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4732—Casein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
- C12Y207/01—Phosphotransferases with an alcohol group as acceptor (2.7.1)
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Food Science & Technology (AREA)
- Biochemistry (AREA)
- Polymers & Plastics (AREA)
- Nutrition Science (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Immunology (AREA)
- Toxicology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Pediatric Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Un método para la modulación de una cinasa administrando a un sujeto una composición nutricional comprendiendo caseína hidrolizada extensivamente, fracciones de caseína hidrolizada extensivamente, combinaciones de las mismas. Una cinasa modulada puede ser una cinasa que regula la señalización inflamatoria, tolerancia inmune, señalización metabólica, ciclo celular y señalización del factor de crecimiento. Dependiendo de la dosis, la composición nutricional puede inhibir una variedad de serina, treonina y tirosina cinasas.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US14/806,877 US20170020950A1 (en) | 2015-07-23 | 2015-07-23 | Methods for modulating kinases |
Publications (1)
Publication Number | Publication Date |
---|---|
AR105427A1 true AR105427A1 (es) | 2017-10-04 |
Family
ID=56236122
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP160102208A AR105427A1 (es) | 2015-07-23 | 2016-07-21 | Métodos para la modulación de cinasas |
Country Status (12)
Country | Link |
---|---|
US (1) | US20170020950A1 (es) |
EP (1) | EP3324991A1 (es) |
CN (1) | CN107949396A (es) |
AR (1) | AR105427A1 (es) |
AU (1) | AU2016296111A1 (es) |
BR (1) | BR112018000594A2 (es) |
CA (1) | CA2993294A1 (es) |
HK (1) | HK1252644A1 (es) |
MX (1) | MX2018000600A (es) |
PH (1) | PH12018500089A1 (es) |
TW (1) | TW201713225A (es) |
WO (1) | WO2017014865A1 (es) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2018227384A1 (zh) * | 2017-06-13 | 2018-12-20 | 浙江海正甦力康生物科技有限公司 | 一种鉴定茶叶品质的方法 |
US20190208807A1 (en) | 2018-01-05 | 2019-07-11 | Mead Johnson Nutrition Company | Nutritional compositions containing milk-derived peptides and uses thereof |
CA3122323A1 (en) * | 2018-12-13 | 2020-06-18 | Societe Des Produits Nestle S.A. | Liquid concentrates formulated for dilution into nutritional products to promote safe swallowing for individuals with dysphagia |
CN110204595A (zh) * | 2019-06-04 | 2019-09-06 | 海普诺凯营养品有限公司 | 一种具有调节b淋巴细胞活性的羊乳酪蛋白水解肽及其制备方法 |
CN110564643B (zh) * | 2019-09-16 | 2021-07-09 | 泰安大凡神农生物有限公司 | 一株具有促骨髓间充质干细胞增殖作用的动物双歧杆菌及其应用 |
CN112753773A (zh) * | 2019-11-11 | 2021-05-07 | 东北农业大学 | 一种降血压牛乳配方奶粉及其制备方法 |
WO2023159125A2 (en) * | 2022-02-17 | 2023-08-24 | Metabico, Inc. | Peptide regulators of metabolism |
CN115536466B (zh) * | 2022-10-09 | 2023-08-25 | 北京中医药大学 | 一种甘草的根瘤菌肥及其制备方法 |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IE61701B1 (en) | 1986-07-17 | 1994-11-30 | Morinaga Milk Industry Co Ltd | Process for producing bovine lactoferrin in high purity |
US5407957A (en) | 1990-02-13 | 1995-04-18 | Martek Corporation | Production of docosahexaenoic acid by dinoflagellates |
DK165090D0 (da) | 1990-07-09 | 1990-07-09 | Kem En Tec As | Konglomererede partikler |
EP1832181A3 (en) | 1991-01-24 | 2010-03-31 | Martek Biosciences Corporation | Microbial oil mixtures and uses thereof |
US5374567A (en) | 1993-05-20 | 1994-12-20 | The United States Of America As Represented By The Secretary Of The Navy | Operational amplifier using bipolar junction transistors in silicon-on-sapphire |
CA2183459A1 (en) | 1994-02-16 | 1995-08-24 | Jan H. Nuijens | Isolation of lactoferrin from milk |
SE9503926D0 (sv) | 1995-11-07 | 1995-11-07 | Pharmacia Biotech Ab | Adsorptionsförfarande och separationsmedium |
WO1999065586A2 (en) | 1998-06-18 | 1999-12-23 | Upfront Chromatography A/S | Expanded bed adsorption system |
MY129566A (en) * | 1999-01-19 | 2007-04-30 | Nestle Sa | A hypoallergenic composition containing tolerogenic peptides inducing oral tolerance |
WO2001085329A2 (en) | 2000-05-12 | 2001-11-15 | Upfront Chromatography A/S | A bed adsorption system |
US6332533B1 (en) | 2000-08-29 | 2001-12-25 | H.H.H. Incorprorated | Media holder mouse pad |
AU2002316806B2 (en) | 2001-06-01 | 2007-10-25 | Upfront Chromatography A/S | Fractionation of protein containing mixtures |
DK1480524T3 (da) | 2002-03-07 | 2013-07-15 | Upfront Chromatography As | Fremgangsmåde til isolering af lactoferrin |
US7618669B2 (en) | 2005-06-01 | 2009-11-17 | Mead Johnson Nutrition Company | Low-lactose partially hydrolyzed infant formula |
EP2533652A1 (en) * | 2010-05-28 | 2012-12-19 | Mead Johnson Nutrition Company | Nutritional compositions |
US8889633B2 (en) * | 2013-03-15 | 2014-11-18 | Mead Johnson Nutrition Company | Nutritional compositions containing a peptide component with anti-inflammatory properties and uses thereof |
US9352020B2 (en) * | 2013-03-15 | 2016-05-31 | Mead Johnson Nutrition Company | Reducing proinflammatory response |
US9289461B2 (en) * | 2013-03-15 | 2016-03-22 | Mead Johnson Nutrition Company | Reducing the risk of autoimmune disease |
-
2015
- 2015-07-23 US US14/806,877 patent/US20170020950A1/en not_active Abandoned
-
2016
- 2016-06-14 BR BR112018000594A patent/BR112018000594A2/pt not_active Application Discontinuation
- 2016-06-14 CN CN201680043237.5A patent/CN107949396A/zh active Pending
- 2016-06-14 AU AU2016296111A patent/AU2016296111A1/en not_active Abandoned
- 2016-06-14 MX MX2018000600A patent/MX2018000600A/es unknown
- 2016-06-14 EP EP16732437.5A patent/EP3324991A1/en not_active Withdrawn
- 2016-06-14 WO PCT/US2016/037330 patent/WO2017014865A1/en active Application Filing
- 2016-06-14 CA CA2993294A patent/CA2993294A1/en not_active Abandoned
- 2016-06-29 TW TW105120604A patent/TW201713225A/zh unknown
- 2016-07-21 AR ARP160102208A patent/AR105427A1/es unknown
-
2018
- 2018-01-10 PH PH12018500089A patent/PH12018500089A1/en unknown
- 2018-09-18 HK HK18111951.4A patent/HK1252644A1/zh unknown
Also Published As
Publication number | Publication date |
---|---|
TW201713225A (zh) | 2017-04-16 |
CN107949396A (zh) | 2018-04-20 |
WO2017014865A1 (en) | 2017-01-26 |
HK1252644A1 (zh) | 2019-05-31 |
EP3324991A1 (en) | 2018-05-30 |
MX2018000600A (es) | 2018-06-06 |
PH12018500089A1 (en) | 2018-07-09 |
AU2016296111A1 (en) | 2018-01-25 |
US20170020950A1 (en) | 2017-01-26 |
BR112018000594A2 (pt) | 2018-09-11 |
CA2993294A1 (en) | 2017-01-26 |
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Legal Events
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