AR094770A1 - Composición masticable para administración oral y proceso para preparar la misma - Google Patents
Composición masticable para administración oral y proceso para preparar la mismaInfo
- Publication number
- AR094770A1 AR094770A1 ARP140100449A ARP140100449A AR094770A1 AR 094770 A1 AR094770 A1 AR 094770A1 AR P140100449 A ARP140100449 A AR P140100449A AR P140100449 A ARP140100449 A AR P140100449A AR 094770 A1 AR094770 A1 AR 094770A1
- Authority
- AR
- Argentina
- Prior art keywords
- composition
- active substance
- oral administration
- surfactant
- optionally
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 8
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 abstract 6
- 239000013543 active substance Substances 0.000 abstract 4
- 239000003086 colorant Substances 0.000 abstract 2
- 239000000796 flavoring agent Substances 0.000 abstract 2
- 235000013355 food flavoring agent Nutrition 0.000 abstract 2
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 2
- 239000001814 pectin Substances 0.000 abstract 2
- 235000010987 pectin Nutrition 0.000 abstract 2
- 229920001277 pectin Polymers 0.000 abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 abstract 2
- 235000021092 sugar substitutes Nutrition 0.000 abstract 2
- 239000004094 surface-active agent Substances 0.000 abstract 2
- 239000003765 sweetening agent Substances 0.000 abstract 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 1
- 239000008186 active pharmaceutical agent Substances 0.000 abstract 1
- 229940088679 drug related substance Drugs 0.000 abstract 1
- 238000001879 gelation Methods 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 239000004615 ingredient Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 229940124531 pharmaceutical excipient Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G3/00—Sweetmeats; Confectionery; Marzipan; Coated or filled products
- A23G3/34—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
- A23G3/36—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds
- A23G3/364—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds containing microorganisms or enzymes; containing paramedical or dietetical agents, e.g. vitamins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G3/00—Sweetmeats; Confectionery; Marzipan; Coated or filled products
- A23G3/34—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
- A23G3/36—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds
- A23G3/48—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds containing plants or parts thereof, e.g. fruits, seeds, extracts
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
- A23L29/20—Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents
- A23L29/206—Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents of vegetable origin
- A23L29/231—Pectin; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Nutrition Science (AREA)
- Polymers & Plastics (AREA)
- Food Science & Technology (AREA)
- Inorganic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Zoology (AREA)
- Physiology (AREA)
- Botany (AREA)
- Microbiology (AREA)
- Dispersion Chemistry (AREA)
- Mycology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Immunology (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Confectionery (AREA)
Abstract
Reivindicación 1: Una composición para administración oral, que comprende: 0,5 - 3,5 %p de pectina de alto contenido en metoxi, 40 - 70 %p de glicerol, 16 - 30 %p de agua, 0 - 2,5 %p de al menos un tensioactivo, 1,5 - 40 %p de al menos otros ingrediente seleccionado del grupo que consiste en: sustitutos del azúcar, agentes saborizantes, agentes colorantes y/o sustancias activas, siendo los porcentajes en peso relativos al peso total de la composición, y estando comprendido el pH de la composición dentro del intervalo de (aproximadamente) 2,8 a aproximadamente 3,2. Reivindicación 5: Una composición farmacéutica que comprende la composición de una cualquiera de las reivindicaciones 1 a 4, que comprende al menos una sustancia activa, siendo dicha sustancia activa una sustancia fármaco, opcionalmente con al menos un excipiente farmacéutico. Reivindicación 7: Un proceso para preparar una composición de una cualquiera de las reivindicaciones 1 a 4 o una composición farmacéutica de una cualquiera de las reivindicaciones 5 ó 6, que comprende las etapas siguientes: (vii) mezclar glicerol, agua, opcionalmente con la(s) sustancia(s) activa(s) y/o los tensioactivo(s), (viii) después de calentar, añadir la pectina de alto contenido en metoxi, (ix) añadir el (los) sustituto(s) del azúcar, agente(s) saborizante(s) y/o agente(s) colorante(s), si los hay (x) calentar la mezcla resultante de la etapa (ii) a una temperatura que oscila de 60ºC a 90ºC, (xi) ajustar el pH con un ácido, (xii) formar y enfriar la composición hasta que se produzca la gelificación.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP13305172 | 2013-02-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR094770A1 true AR094770A1 (es) | 2015-08-26 |
Family
ID=47739180
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP140100449A AR094770A1 (es) | 2013-02-14 | 2014-02-13 | Composición masticable para administración oral y proceso para preparar la misma |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US9474713B2 (es) |
| EP (1) | EP2956011B1 (es) |
| JP (1) | JP6346623B2 (es) |
| KR (1) | KR20150116861A (es) |
| CN (1) | CN105007750A (es) |
| AR (1) | AR094770A1 (es) |
| AU (1) | AU2014217965B2 (es) |
| BR (1) | BR112015018200B1 (es) |
| CA (1) | CA2900597C (es) |
| HU (1) | HUE038489T2 (es) |
| IL (1) | IL239958A (es) |
| MX (1) | MX359887B (es) |
| PL (1) | PL2956011T3 (es) |
| RU (1) | RU2015138710A (es) |
| SG (1) | SG11201505541VA (es) |
| TW (1) | TWI622408B (es) |
| WO (1) | WO2014124981A1 (es) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2999937B1 (fr) | 2012-12-21 | 2015-01-09 | Sanofi Sa | Unite solide a haute teneur en fexofenadine et son procede de preparation |
| AU2018239993B2 (en) * | 2017-03-20 | 2024-01-25 | Bayer Healthcare Llc | Chewable gel products for active pharmaceutical ingredients |
| EA202091127A1 (ru) * | 2017-11-02 | 2020-09-22 | Замбон С.П.А. | Фармацевтические композиции, включающие сафинамид |
| EP3549579A1 (en) | 2018-04-03 | 2019-10-09 | Sanofi Winthrop Industrie | Oral gum formulation and fabrication process thereof |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6723348B2 (en) * | 2001-11-16 | 2004-04-20 | Ethypharm | Orodispersible tablets containing fexofenadine |
| WO2007017905A1 (en) * | 2005-08-05 | 2007-02-15 | Lupin Limited | Oral pharmaceutical suspension compositions of fexofenadine |
| US9155772B2 (en) * | 2008-12-08 | 2015-10-13 | Philip Morris Usa Inc. | Soft, chewable and orally dissolvable and/or disintegrable products |
| CN101628117B (zh) * | 2009-08-18 | 2011-02-16 | 北京航洋胶囊技术有限公司 | 一种咀嚼软胶囊皮、咀嚼软胶囊药物及其制备方法 |
| EP2512446B1 (en) * | 2009-12-16 | 2015-04-08 | Shasun Pharmaceuticals Limited | Composition of dexibuprofen transdermal hydrogel |
| US20120251484A1 (en) * | 2011-03-31 | 2012-10-04 | Cp Kelco Aps | Cold prepared gel and method for making same |
| KR101303479B1 (ko) | 2011-07-28 | 2013-09-06 | (주)씨엘팜 | 가식성 필름형성 조성물 및 약물이 함유된 가식성 필름형 제제 |
| FR2999937B1 (fr) | 2012-12-21 | 2015-01-09 | Sanofi Sa | Unite solide a haute teneur en fexofenadine et son procede de preparation |
-
2014
- 2014-02-12 CA CA2900597A patent/CA2900597C/en active Active
- 2014-02-12 KR KR1020157022247A patent/KR20150116861A/ko not_active Application Discontinuation
- 2014-02-12 SG SG11201505541VA patent/SG11201505541VA/en unknown
- 2014-02-12 RU RU2015138710A patent/RU2015138710A/ru not_active Application Discontinuation
- 2014-02-12 WO PCT/EP2014/052746 patent/WO2014124981A1/en active Application Filing
- 2014-02-12 PL PL14703892T patent/PL2956011T3/pl unknown
- 2014-02-12 JP JP2015557416A patent/JP6346623B2/ja active Active
- 2014-02-12 HU HUE14703892A patent/HUE038489T2/hu unknown
- 2014-02-12 MX MX2015010486A patent/MX359887B/es active IP Right Grant
- 2014-02-12 CN CN201480008792.5A patent/CN105007750A/zh active Pending
- 2014-02-12 AU AU2014217965A patent/AU2014217965B2/en active Active
- 2014-02-12 EP EP14703892.1A patent/EP2956011B1/en active Active
- 2014-02-12 BR BR112015018200-3A patent/BR112015018200B1/pt active IP Right Grant
- 2014-02-12 US US14/767,527 patent/US9474713B2/en active Active
- 2014-02-13 AR ARP140100449A patent/AR094770A1/es unknown
- 2014-02-14 TW TW103104989A patent/TWI622408B/zh not_active IP Right Cessation
-
2015
- 2015-07-15 IL IL239958A patent/IL239958A/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| AU2014217965A1 (en) | 2015-08-20 |
| SG11201505541VA (en) | 2015-08-28 |
| HUE038489T2 (hu) | 2018-10-29 |
| BR112015018200A2 (pt) | 2017-07-18 |
| MX359887B (es) | 2018-10-15 |
| RU2015138710A (ru) | 2017-03-20 |
| JP6346623B2 (ja) | 2018-06-20 |
| EP2956011A1 (en) | 2015-12-23 |
| US9474713B2 (en) | 2016-10-25 |
| AU2014217965B2 (en) | 2017-03-23 |
| JP2016507579A (ja) | 2016-03-10 |
| EP2956011B1 (en) | 2018-03-28 |
| US20150374622A1 (en) | 2015-12-31 |
| IL239958A (en) | 2017-11-30 |
| CA2900597C (en) | 2021-11-02 |
| CN105007750A (zh) | 2015-10-28 |
| IL239958A0 (en) | 2015-08-31 |
| PL2956011T3 (pl) | 2018-09-28 |
| BR112015018200B1 (pt) | 2020-11-03 |
| TWI622408B (zh) | 2018-05-01 |
| KR20150116861A (ko) | 2015-10-16 |
| TW201440821A (zh) | 2014-11-01 |
| WO2014124981A1 (en) | 2014-08-21 |
| CA2900597A1 (en) | 2014-08-21 |
| MX2015010486A (es) | 2015-10-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |