AR093454A1 - Piridiloxialquilcarboxamidas y su uso como endoparasiticidas y nematicidas - Google Patents

Piridiloxialquilcarboxamidas y su uso como endoparasiticidas y nematicidas

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Publication number
AR093454A1
AR093454A1 ARP130104156A ARP130104156A AR093454A1 AR 093454 A1 AR093454 A1 AR 093454A1 AR P130104156 A ARP130104156 A AR P130104156A AR P130104156 A ARP130104156 A AR P130104156A AR 093454 A1 AR093454 A1 AR 093454A1
Authority
AR
Argentina
Prior art keywords
polysubstituted
alkyl
mono
haloalkyl
alkoxy
Prior art date
Application number
ARP130104156A
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English (en)
Inventor
Dr Greul Jrg
Dr Schwarz Hans
Georg - Grgens Ulrich
Dr Welz Claudia
Dr Alig Bernd
Dr Becker Angela
Dr Portz Daniela
Dr Ilg Kerstin
Original Assignee
Bayer Cropscience Ag
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Application filed by Bayer Cropscience Ag filed Critical Bayer Cropscience Ag
Publication of AR093454A1 publication Critical patent/AR093454A1/es

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/64—One oxygen atom attached in position 2 or 6
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
    • A01N43/40—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/50—1,3-Diazoles; Hydrogenated 1,3-diazoles
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/56—1,2-Diazoles; Hydrogenated 1,2-diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/70—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/84—Nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Environmental Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • Pest Control & Pesticides (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Agronomy & Crop Science (AREA)
  • Plant Pathology (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pretreatment Of Seeds And Plants (AREA)

Abstract

La presente solicitud se refiere a piridiloxialquilcarboxamidas de la fórmula (1) y a su uso como endoparasiticidas contra endoparásitos en animales o en seres humanos, así como también a su uso como nematicidas para combatir nematodos fitopatógenos, además endoparasiticidas y nematicidas que contienen piridiloxialquilcarboxamidas. Reivindicación 1: Compuestos de la fórmula (1) en la que Q representa los elementos estructurales seleccionados del grupo de fórmulas (2), estando definido n para cada Q respectivamente como se indica; Y representa hidrógeno o representa alquilo C₁₋₁₀, alquenilo C₂₋₁₀, alquinilo C₂₋₁₀, haloalquilo C₁₋₁₀, haloalquenilo C₂₋₁₀, haloalquinilo C₂₋₁₀, alcoxi C₁₋₁₀, alqueniloxi C₂₋₁₀, alquiniloxi C₃₋₁₀, cicloalquil C₃₋₁₄-alquilo C₁₋₁₀ dado el caso mono- o polisustituidos con M² o representa un grupo cíclico de 3 a 14 miembros dado el caso mono- o polisustituido con M²; W representa oxígeno o azufre; L² representa -C(R²¹,R²²)-; L³ representa -C(R³¹,R³²)-; M¹, M² y M³ representan cada uno independientemente entre sí hidrógeno, halógeno, ciano, nitro, OH, alquilo C₁₋₁₀, haloalquilo C₁₋₁₀, alcoxi C₁₋₁₀, haloalcoxi C₁₋₁₀, alquiltio C₁₋₁₀, haloalquiltio C₁₋₁₀, alquilsulfonilo C₁₋₁₀, haloalquilsulfonilo C₁₋₁₀, alquilsulfanilo C₁₋₁₀, haloalquilsulfanilo C₁₋₁₀, o representan (un grupo cíclico de 3 a 14 miembros)-O-; M⁴ representa hidrógeno, halógeno, ciano, nitro, OH, alquilo C₁₋₁₀, haloalquilo C₁₋₁₀, alcoxi C₁₋₁₀, haloalcoxi C₁₋₁₀, alquiltio C₁₋₁₀, haloalquiltio C₁₋₁₀, alquilsulfonilo C₁₋₁₀, haloalquilsulfonilo C₁₋₁₀, alquilsulfanilo C₁₋₁₀, haloalquilsulfanilo C₁₋₁₀, o representa (un grupo cíclico de 3 a 14 miembros)-O-; k representa 1, 2, ó 3; R²¹, R²² representan en cada caso independientemente entre sí hidrógeno, halógeno o alquilo C₁₋₁₀, alquenilo C₂₋₁₀, alquinilo C₂₋₁₀, haloalquilo C₁₋₁₀, haloalquenilo C₂₋₁₀, haloalquinilo C₂₋₁₀, alcoxi C₁₋₁₀, haloalcoxi C₁₋₁₀, alqueniloxi C₂₋₁₀, alquiniloxi C₃₋₁₀, cicloalquil C₃₋₁₄-alquilo C₁₋₁₀ dado el caso mono- o polisustituidos con M² o representan un grupo cíclico de 3 a 14 miembros mono- o dado el caso polisustituidos con M²; R²¹, R²² juntos representan un grupo heterocíclico de 3 a 10 miembros o carbocíclico de 3 a 14 miembros enlazado con espiro cada uno dado el caso mono- o polisustituido con M²; R³¹, R³² representan en cada caso independientemente entre sí hidrógeno, halógeno o alquilo C₁₋₁₀, alquenilo C₂₋₁₀, alquinilo C₂₋₁₀, haloalquilo C₁₋₁₀, haloalquenilo C₂₋₁₀, haloalquinilo C₂₋₁₀, cicloalquil C₃₋₁₄-alquilo C₁₋₁₀ dado el caso mono- o polisustituido con M² o representan un grupo cíclico de 3 a 14 miembros dado el caso mono- o polisustituido con M²; R³¹, R³² juntos representan un grupo heterocíclico de 3 a 10 miembros o carbocíclico de 3 a 14 miembros enlazado con espiro cada uno dado el caso mono- o polisustituido con M⁵; y M⁵ representa cada vez independientemente entre sí halógeno, formilo, ciano, nitro, alquilo C₁₋₁₀, haloalquilo C₁₋₁₀, alquenilo C₂₋₁₀, haloalquenilo C₂₋₁₀, alquinilo C₂₋₁₀, haloalquinilo C₂₋₁₀, alcoxi C₁₋₁₀, haloalcoxi C₁₋₁₀, alqueniloxi C₂₋₁₀, haloalquenoxi C₂₋₁₀, alquiniloxi C₃₋₁₀, haloalquinoxi C₃₋₁₀, alquiltio C₁₋₁₀, haloalquiltio C₁₋₁₀, alqueniltio C₂₋₁₀, haloalqueniltio C₂₋₁₀, alquiniltio C₃₋₁₀, haloalquiniltio C₃₋₁₀, alquilsulfonilo C₁₋₁₀, haloalquilsulfonilo C₁₋₁₀, alquenilsulfonilo C₂₋₁₀, haloalquenilsulfonilo C₂₋₁₀, alquinilsulfonilo C₃₋₁₀, haloalquinilsulfonilo C₃₋₁₀, alquilsulfanilo C₁₋₁₀, haloalquilsulfanilo C₁₋₁₀, alquenilsulfanilo C₂₋₁₀, haloalquenilsulfanilo C₂₋₁₀, alquinilsulfanilo C₃₋₁₀, haloalquinilsulfanilo C₃₋₁₀, alquilcarbonilo C₁₋₁₀, haloalquilcarbonilo C₁₋₁₀, alquenilcarbonilo C₂₋₁₀, haloalquenilcarbonilo C₂₋₁₀, alquinilcarbonilo C₂₋₁₀, haloalquinilcarbonilo C₂₋₁₀, alcoxilcarbonilo C₁₋₁₀, haloalcoxilcarbonilo C₁₋₁₀, alquenoxicarbonilo C₂₋₁₀, haloalquenoxicarbonilo C₂₋₁₀, alquinoxicarbonilo C₃₋₁₀, haloalquinoxicarbonilo C₃₋₁₀, alquilcarboniloxi C₁₋₁₀, haloalquilcarboniloxi C₁₋₁₀, alquenilcarboniloxi C₂₋₁₀, haloalquenilcarboniloxi C₂₋₁₀, alquinilcarboniloxi C₂₋₁₀, haloalquinilcarboniloxi C₂₋₁₀, un grupo cíclico de 3 a 14 miembros; así como también sales, N-óxidos y formas tautómeras de los compuestos de la fórmula (1) salvo los compuestos N-[2-(piridin-2-iloxi)etil]-4-trifluorometil)nicotinamida de fórmula (3) y 4-(trifluorometil)-N(2-{[5-(trifluorometil)piridin-2-il]oxi}etil)nicotinamida de fórmula (4).
ARP130104156A 2012-11-13 2013-11-12 Piridiloxialquilcarboxamidas y su uso como endoparasiticidas y nematicidas AR093454A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP12192446.8A EP2730570A1 (de) 2012-11-13 2012-11-13 Pyridyloxyalkylcarboxamide und deren Verwendung als Endoparasitizide und Nematizide

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AR093454A1 true AR093454A1 (es) 2015-06-10

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US (1) US9556121B2 (es)
EP (2) EP2730570A1 (es)
JP (1) JP6364014B2 (es)
AR (1) AR093454A1 (es)
AU (2) AU2013346957B2 (es)
BR (1) BR112015010528A2 (es)
CA (1) CA2890826A1 (es)
CR (1) CR20150251A (es)
EC (1) ECSP15018751A (es)
ES (1) ES2684692T3 (es)
MX (1) MX2015005958A (es)
PH (1) PH12015501054A1 (es)
TW (1) TW201439063A (es)
UY (1) UY35134A (es)
WO (1) WO2014076015A1 (es)

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CR20150251A (es) 2015-06-19
BR112015010528A2 (pt) 2017-07-11
AU2018201345A1 (en) 2018-03-15
JP2016505520A (ja) 2016-02-25
EP2730570A1 (de) 2014-05-14
WO2014076015A1 (de) 2014-05-22
AU2013346957B2 (en) 2018-03-08
JP6364014B2 (ja) 2018-07-25
AU2013346957A1 (en) 2015-05-21
EP2920163B1 (de) 2018-05-02
PH12015501054A1 (en) 2015-07-27
ECSP15018751A (es) 2016-01-29
CA2890826A1 (en) 2014-05-22
UY35134A (es) 2014-06-30
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TW201439063A (zh) 2014-10-16

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