AR089245A1 - Procedimiento de purificacion de factor viii - Google Patents
Procedimiento de purificacion de factor viiiInfo
- Publication number
- AR089245A1 AR089245A1 ARP120104721A AR089245A1 AR 089245 A1 AR089245 A1 AR 089245A1 AR P120104721 A ARP120104721 A AR P120104721A AR 089245 A1 AR089245 A1 AR 089245A1
- Authority
- AR
- Argentina
- Prior art keywords
- purification procedure
- fviii
- procedure viii
- factor purification
- composition
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
- C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Hematology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
Procedimiento de purificación de factor VIII (Factor de coagulación VIII). La presente se refiere a un procedimiento para la purificación de FVIII por cromatografia de afinidad, caracterizado porque se pone en contacto una composición que comprende FVIII con un ligando de afinidad, particularmente, con un anticuerpo anti-FVIII, en condiciones en las que el FVIII se une al ligando de afinidad, pero no a ningún FVW, que puede estar o no presente en la composición.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161581723P | 2011-12-30 | 2011-12-30 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR089245A1 true AR089245A1 (es) | 2014-08-06 |
Family
ID=47561688
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP120104721 AR089245A1 (es) | 2011-12-30 | 2012-12-14 | Procedimiento de purificacion de factor viii |
Country Status (4)
Country | Link |
---|---|
AR (1) | AR089245A1 (es) |
AU (1) | AU2012324020A1 (es) |
UY (1) | UY34501A (es) |
WO (1) | WO2013098676A1 (es) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2018111010A1 (ko) * | 2016-12-14 | 2018-06-21 | (주) 팬젠 | 항-혈액응고 제viii인자 항체 및 그 용도 |
KR101989779B1 (ko) * | 2016-12-14 | 2019-06-17 | (주) 팬젠 | 항-혈액응고 제viii인자 항체 및 그 용도 |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4965199A (en) | 1984-04-20 | 1990-10-23 | Genentech, Inc. | Preparation of functional human factor VIII in mammalian cells using methotrexate based selection |
CA1339946C (en) * | 1987-03-31 | 1998-07-07 | Michael J. Griffith | Ultrapurification process for polypeptides |
US5149637A (en) | 1987-04-06 | 1992-09-22 | Scripps Clinic & Research Foundation | Recombinant Factor VIIIC fragments |
US5200510A (en) * | 1987-06-16 | 1993-04-06 | Zymogenetics, Inc. | Method for purifying factor viii:c, von willebrand factor and complexes thereof |
SE465222C5 (sv) | 1989-12-15 | 1998-02-10 | Pharmacia & Upjohn Ab | Ett rekombinant, humant faktor VIII-derivat och förfarande för dess framställning |
FR2657884B1 (fr) | 1990-02-05 | 1994-09-02 | Tm Innovation | Procede pour la preparation du facteur viii humain et d'analogues du facteur viii. |
US5661008A (en) | 1991-03-15 | 1997-08-26 | Kabi Pharmacia Ab | Recombinant human factor VIII derivatives |
AT403765B (de) | 1996-04-12 | 1998-05-25 | Immuno Ag | Verfahren zur herstellung einer präparation enthaltend einen hochgereinigten komplex |
US5804420A (en) | 1997-04-18 | 1998-09-08 | Bayer Corporation | Preparation of recombinant Factor VIII in a protein free medium |
US6855544B1 (en) | 1999-04-15 | 2005-02-15 | Crucell Holland B.V. | Recombinant protein production in a human cell |
DE19932688B4 (de) | 1999-07-13 | 2009-10-08 | Scil Proteins Gmbh | Design von Beta-Faltblatt-Proteinen des gamma-II-kristallins antikörperähnlichen |
GB9917027D0 (en) | 1999-07-20 | 1999-09-22 | Affibody Technology Sweeden Ab | In vitro selection and optional identification of polypeptides using solid support carriers |
JP2009502149A (ja) | 2005-07-29 | 2009-01-29 | ライフ・サイエンシーズ・リサーチ・パートナーズ・フェレニゲング・ゾンデル・ウィンストーメルク | 新規な抗第viii因子抗体 |
EP1876183A1 (en) * | 2006-07-04 | 2008-01-09 | Technische Universität München | Minimized small peptides with high affinity for factor VIII and factor VIII-like proteins |
US8759293B2 (en) | 2009-11-13 | 2014-06-24 | Grifols Therapeutics Inc. | von Willebrand factor (vWF)-containing preparations, and methods, kits, and uses related thereto |
-
2012
- 2012-11-28 AU AU2012324020A patent/AU2012324020A1/en not_active Abandoned
- 2012-11-28 WO PCT/IB2012/056802 patent/WO2013098676A1/en active Application Filing
- 2012-12-07 UY UY34501A patent/UY34501A/es not_active Application Discontinuation
- 2012-12-14 AR ARP120104721 patent/AR089245A1/es not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
WO2013098676A1 (en) | 2013-07-04 |
AU2012324020A1 (en) | 2013-07-18 |
UY34501A (es) | 2013-09-02 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA | Abandonment or withdrawal |