AR089245A1 - Procedimiento de purificacion de factor viii - Google Patents

Procedimiento de purificacion de factor viii

Info

Publication number
AR089245A1
AR089245A1 ARP120104721A AR089245A1 AR 089245 A1 AR089245 A1 AR 089245A1 AR P120104721 A ARP120104721 A AR P120104721A AR 089245 A1 AR089245 A1 AR 089245A1
Authority
AR
Argentina
Prior art keywords
purification procedure
fviii
procedure viii
factor purification
composition
Prior art date
Application number
Other languages
English (en)
Inventor
Chamberlain Dean
Original Assignee
Grifols Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Grifols Sa filed Critical Grifols Sa
Publication of AR089245A1 publication Critical patent/AR089245A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745Blood coagulation or fibrinolysis factors
    • C07K14/755Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

Procedimiento de purificación de factor VIII (Factor de coagulación VIII). La presente se refiere a un procedimiento para la purificación de FVIII por cromatografia de afinidad, caracterizado porque se pone en contacto una composición que comprende FVIII con un ligando de afinidad, particularmente, con un anticuerpo anti-FVIII, en condiciones en las que el FVIII se une al ligando de afinidad, pero no a ningún FVW, que puede estar o no presente en la composición.
ARP120104721 2011-12-30 2012-12-14 Procedimiento de purificacion de factor viii AR089245A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201161581723P 2011-12-30 2011-12-30

Publications (1)

Publication Number Publication Date
AR089245A1 true AR089245A1 (es) 2014-08-06

Family

ID=47561688

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP120104721 AR089245A1 (es) 2011-12-30 2012-12-14 Procedimiento de purificacion de factor viii

Country Status (4)

Country Link
AR (1) AR089245A1 (es)
AU (1) AU2012324020A1 (es)
UY (1) UY34501A (es)
WO (1) WO2013098676A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018111010A1 (ko) * 2016-12-14 2018-06-21 (주) 팬젠 항-혈액응고 제viii인자 항체 및 그 용도
KR101989779B1 (ko) * 2016-12-14 2019-06-17 (주) 팬젠 항-혈액응고 제viii인자 항체 및 그 용도

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4965199A (en) 1984-04-20 1990-10-23 Genentech, Inc. Preparation of functional human factor VIII in mammalian cells using methotrexate based selection
CA1339946C (en) * 1987-03-31 1998-07-07 Michael J. Griffith Ultrapurification process for polypeptides
US5149637A (en) 1987-04-06 1992-09-22 Scripps Clinic & Research Foundation Recombinant Factor VIIIC fragments
US5200510A (en) * 1987-06-16 1993-04-06 Zymogenetics, Inc. Method for purifying factor viii:c, von willebrand factor and complexes thereof
SE465222C5 (sv) 1989-12-15 1998-02-10 Pharmacia & Upjohn Ab Ett rekombinant, humant faktor VIII-derivat och förfarande för dess framställning
FR2657884B1 (fr) 1990-02-05 1994-09-02 Tm Innovation Procede pour la preparation du facteur viii humain et d'analogues du facteur viii.
US5661008A (en) 1991-03-15 1997-08-26 Kabi Pharmacia Ab Recombinant human factor VIII derivatives
AT403765B (de) 1996-04-12 1998-05-25 Immuno Ag Verfahren zur herstellung einer präparation enthaltend einen hochgereinigten komplex
US5804420A (en) 1997-04-18 1998-09-08 Bayer Corporation Preparation of recombinant Factor VIII in a protein free medium
US6855544B1 (en) 1999-04-15 2005-02-15 Crucell Holland B.V. Recombinant protein production in a human cell
DE19932688B4 (de) 1999-07-13 2009-10-08 Scil Proteins Gmbh Design von Beta-Faltblatt-Proteinen des gamma-II-kristallins antikörperähnlichen
GB9917027D0 (en) 1999-07-20 1999-09-22 Affibody Technology Sweeden Ab In vitro selection and optional identification of polypeptides using solid support carriers
JP2009502149A (ja) 2005-07-29 2009-01-29 ライフ・サイエンシーズ・リサーチ・パートナーズ・フェレニゲング・ゾンデル・ウィンストーメルク 新規な抗第viii因子抗体
EP1876183A1 (en) * 2006-07-04 2008-01-09 Technische Universität München Minimized small peptides with high affinity for factor VIII and factor VIII-like proteins
US8759293B2 (en) 2009-11-13 2014-06-24 Grifols Therapeutics Inc. von Willebrand factor (vWF)-containing preparations, and methods, kits, and uses related thereto

Also Published As

Publication number Publication date
WO2013098676A1 (en) 2013-07-04
AU2012324020A1 (en) 2013-07-18
UY34501A (es) 2013-09-02

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Legal Events

Date Code Title Description
FA Abandonment or withdrawal