AR087843A1 - Formas polimorficas de n-((s)-3-amino-1-(hidroxiamino)-3-metil-1-oxobutan-2-il)-4-(((1r,2r)-2-(hidroximetil)ciclopropil)buta-1,3-dinil)benzamida - Google Patents

Formas polimorficas de n-((s)-3-amino-1-(hidroxiamino)-3-metil-1-oxobutan-2-il)-4-(((1r,2r)-2-(hidroximetil)ciclopropil)buta-1,3-dinil)benzamida

Info

Publication number
AR087843A1
AR087843A1 ARP120103351A ARP120103351A AR087843A1 AR 087843 A1 AR087843 A1 AR 087843A1 AR P120103351 A ARP120103351 A AR P120103351A AR P120103351 A ARP120103351 A AR P120103351A AR 087843 A1 AR087843 A1 AR 087843A1
Authority
AR
Argentina
Prior art keywords
oxobutan
buta
amino
methyl
polymorphic forms
Prior art date
Application number
ARP120103351A
Other languages
English (en)
Inventor
Annasaheb Kasar Ramesh
Trend Raissa
Original Assignee
Achaogen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Achaogen Inc filed Critical Achaogen Inc
Publication of AR087843A1 publication Critical patent/AR087843A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
    • C07C259/04—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
    • C07C259/06—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to hydrogen atoms or to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/42—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/02—Systems containing only non-condensed rings with a three-membered ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Formas polimórficas de N-((S)-3-amino-1-(hidroxiamino)-3-metil-1-oxobutan-2-il)-4-(((1R,2R)-2-(hidroximetil)ciclopropil)buta-1,3-dinil)benzamida (Compuesto I). También, procesos para hacer las mismas, así como composiciones y métodos relacionados, en particular con respecto al tratamiento de infecciones bacterianas.
ARP120103351A 2011-09-12 2012-09-12 Formas polimorficas de n-((s)-3-amino-1-(hidroxiamino)-3-metil-1-oxobutan-2-il)-4-(((1r,2r)-2-(hidroximetil)ciclopropil)buta-1,3-dinil)benzamida AR087843A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201161533628P 2011-09-12 2011-09-12

Publications (1)

Publication Number Publication Date
AR087843A1 true AR087843A1 (es) 2014-04-23

Family

ID=47049347

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP120103351A AR087843A1 (es) 2011-09-12 2012-09-12 Formas polimorficas de n-((s)-3-amino-1-(hidroxiamino)-3-metil-1-oxobutan-2-il)-4-(((1r,2r)-2-(hidroximetil)ciclopropil)buta-1,3-dinil)benzamida

Country Status (4)

Country Link
US (1) US20150203444A1 (es)
AR (1) AR087843A1 (es)
TW (1) TW201315710A (es)
WO (1) WO2013039947A1 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107021895A (zh) 2007-06-12 2017-08-08 尔察祯有限公司 抗菌剂
WO2013170165A1 (en) 2012-05-10 2013-11-14 Achaogen, Inc. Antibacterial agents
EP4286001A3 (en) 2016-04-25 2024-07-17 Duke University Benzoylglycine derivatives and methods of making and using same
ITUA20164306A1 (it) * 2016-06-13 2017-12-13 Dr Tech S R L Dispositivo e metodo per il riempimento di contenitori con un liquido, in particolare per l’imbottigliamento
AR108864A1 (es) 2016-06-23 2018-10-03 Achaogen Inc Agentes antibacterianos
CN110563611B (zh) * 2019-09-19 2021-02-02 中国医学科学院医药生物技术研究所 一种异羟肟酸类衍生物及其制备方法和应用
CN116730870B (zh) * 2023-08-08 2023-10-13 中国医学科学院医药生物技术研究所 异羟肟酸类化合物或其可药用盐、及其用途和制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU5426398A (en) 1996-10-28 1998-05-22 Versicor Inc Methods for solid-phase synthesis of hydroxylamine compounds and derivatives, and combinatorial libraries thereof
AU3979200A (en) 1999-04-09 2000-11-14 British Biotech Pharmaceuticals Limited Antimicrobial agents
CA2512582C (en) 2003-01-08 2014-07-08 University Of Washington Antibacterial agents
CN107021895A (zh) 2007-06-12 2017-08-08 尔察祯有限公司 抗菌剂

Also Published As

Publication number Publication date
US20150203444A1 (en) 2015-07-23
TW201315710A (zh) 2013-04-16
WO2013039947A1 (en) 2013-03-21

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