AR086576A1 - Composiciones de cb-183,315 y metodos relacionados - Google Patents
Composiciones de cb-183,315 y metodos relacionadosInfo
- Publication number
- AR086576A1 AR086576A1 ARP120101868A ARP120101868A AR086576A1 AR 086576 A1 AR086576 A1 AR 086576A1 AR P120101868 A ARP120101868 A AR P120101868A AR P120101868 A ARP120101868 A AR P120101868A AR 086576 A1 AR086576 A1 AR 086576A1
- Authority
- AR
- Argentina
- Prior art keywords
- compositions
- related methods
- solid
- aqueous solution
- trehalose
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title abstract 2
- 239000007787 solid Substances 0.000 abstract 3
- 239000007864 aqueous solution Substances 0.000 abstract 2
- 238000002360 preparation method Methods 0.000 abstract 2
- HDTRYLNUVZCQOY-UHFFFAOYSA-N α-D-glucopyranosyl-α-D-glucopyranoside Natural products OC1C(O)C(O)C(CO)OC1OC1C(O)C(O)C(O)C(CO)O1 HDTRYLNUVZCQOY-UHFFFAOYSA-N 0.000 abstract 1
- 229920002307 Dextran Polymers 0.000 abstract 1
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 abstract 1
- 229930006000 Sucrose Natural products 0.000 abstract 1
- HDTRYLNUVZCQOY-WSWWMNSNSA-N Trehalose Natural products O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O1 HDTRYLNUVZCQOY-WSWWMNSNSA-N 0.000 abstract 1
- HDTRYLNUVZCQOY-LIZSDCNHSA-N alpha,alpha-trehalose Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 HDTRYLNUVZCQOY-LIZSDCNHSA-N 0.000 abstract 1
- 238000004108 freeze drying Methods 0.000 abstract 1
- FZWBNHMXJMCXLU-BLAUPYHCSA-N isomaltotriose Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)[C@@H](OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C=O)O1 FZWBNHMXJMCXLU-BLAUPYHCSA-N 0.000 abstract 1
- 238000001694 spray drying Methods 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 239000005720 sucrose Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Inorganic Chemistry (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Organic Chemistry (AREA)
- Communicable Diseases (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161490584P | 2011-05-26 | 2011-05-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR086576A1 true AR086576A1 (es) | 2014-01-08 |
Family
ID=46208839
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP120101868A AR086576A1 (es) | 2011-05-26 | 2012-05-28 | Composiciones de cb-183,315 y metodos relacionados |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US20130109633A1 (enExample) |
| EP (1) | EP2714012A1 (enExample) |
| JP (1) | JP2014515371A (enExample) |
| KR (1) | KR20140037877A (enExample) |
| CN (1) | CN103687589A (enExample) |
| AR (1) | AR086576A1 (enExample) |
| BR (1) | BR112013030369A2 (enExample) |
| CA (1) | CA2837174A1 (enExample) |
| MX (1) | MX2013013760A (enExample) |
| RU (1) | RU2013157188A (enExample) |
| TW (1) | TW201300124A (enExample) |
| WO (1) | WO2012162567A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2017173932A1 (en) * | 2016-04-08 | 2017-10-12 | Versitech Limited | Antibacterial cyclic lipopeptides |
| US11667674B2 (en) | 2016-04-08 | 2023-06-06 | Versitech Limited | Antibacterial cyclic lipopeptides |
| US10647746B2 (en) | 2016-04-08 | 2020-05-12 | Versitech Limited | Antibacterial cyclic lipopeptides |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL150224A0 (en) * | 1999-12-15 | 2002-12-01 | Cubist Pharm Inc | Lipopeptides and pharmaceutical compositions containing the same |
| AU2001267011B2 (en) * | 2000-06-21 | 2006-02-02 | Cubist Pharmaceuticals, Inc. | Compositions and methods to improve the oral absorption of antimicrobial agents |
| JP2004525108A (ja) * | 2000-12-18 | 2004-08-19 | キュービスト ファーマスーティカルズ インコーポレイテッド | 精製リポペプチドの調製方法 |
| RU2007121705A (ru) * | 2004-11-12 | 2008-12-20 | Кьюбист Фармасьютикалз | Антиинфекционные липопептиды |
| US8158152B2 (en) * | 2005-11-18 | 2012-04-17 | Scidose Llc | Lyophilization process and products obtained thereby |
| NZ594019A (en) | 2008-12-22 | 2013-08-30 | Cubist Pharm Inc | Novel antibacterial agents for the treatment of gram positive infections |
| JP5491119B2 (ja) * | 2009-10-02 | 2014-05-14 | 日東電工株式会社 | 薬物含有微粒子を含む医薬組成物およびその製造方法 |
| CN102060914B (zh) * | 2009-11-13 | 2014-09-17 | 华东理工大学 | 海洋芽孢杆菌b-9987产脂肽类化合物及其制备和应用 |
| CA2781666C (en) * | 2009-11-23 | 2017-02-21 | Cubist Pharmaceuticals, Inc. | Lipopeptide compositions and related methods |
| US20110124551A1 (en) * | 2009-11-23 | 2011-05-26 | Eagle Pharmaceuticals, Inc. | Formulations of daptomycin |
-
2012
- 2012-05-24 MX MX2013013760A patent/MX2013013760A/es unknown
- 2012-05-24 BR BR112013030369A patent/BR112013030369A2/pt not_active IP Right Cessation
- 2012-05-24 RU RU2013157188/15A patent/RU2013157188A/ru not_active Application Discontinuation
- 2012-05-24 KR KR1020137033768A patent/KR20140037877A/ko not_active Withdrawn
- 2012-05-24 JP JP2014512126A patent/JP2014515371A/ja active Pending
- 2012-05-24 CN CN201280025551.2A patent/CN103687589A/zh active Pending
- 2012-05-24 CA CA2837174A patent/CA2837174A1/en not_active Abandoned
- 2012-05-24 EP EP12725988.5A patent/EP2714012A1/en not_active Withdrawn
- 2012-05-24 WO PCT/US2012/039476 patent/WO2012162567A1/en not_active Ceased
- 2012-05-25 TW TW101118841A patent/TW201300124A/zh unknown
- 2012-05-25 US US13/481,009 patent/US20130109633A1/en not_active Abandoned
- 2012-05-28 AR ARP120101868A patent/AR086576A1/es unknown
-
2013
- 2013-10-07 US US14/047,701 patent/US20140135273A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| BR112013030369A2 (pt) | 2016-12-13 |
| RU2013157188A (ru) | 2015-07-10 |
| CN103687589A (zh) | 2014-03-26 |
| KR20140037877A (ko) | 2014-03-27 |
| JP2014515371A (ja) | 2014-06-30 |
| TW201300124A (zh) | 2013-01-01 |
| WO2012162567A1 (en) | 2012-11-29 |
| MX2013013760A (es) | 2014-01-08 |
| US20130109633A1 (en) | 2013-05-02 |
| US20140135273A1 (en) | 2014-05-15 |
| CA2837174A1 (en) | 2012-11-29 |
| EP2714012A1 (en) | 2014-04-09 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BR112015013822A2 (pt) | método de vaso único para a síntese de cu-ssz-13, o composto obtido através do método e utilização do mesmo | |
| CL2019002190A1 (es) | Reducción de la viscosidad de formulaciones farmacéuticas que comprende una proteína terapéutica a una concentración de al menos 70 mg/ml, donde la proteína terapéutica no es un anticuerpo (divisional solicitud 201700984) | |
| WO2017070616A3 (en) | Sexually transmitted disease vaccines | |
| EA201590890A1 (ru) | Производные 5-фтор-n-(пиридин-2-ил)пиридин-2-амина, содержащие сульфоксиминовую группу | |
| WO2017070626A3 (en) | Respiratory virus vaccines | |
| MX2018004916A (es) | Vacuna contra el virus de la influenza de amplio espectro. | |
| PE20181400A1 (es) | Formulacion farmaceutica acuosa del anticuerpo anti-pd-l1 avelumab | |
| BR112015015031A2 (pt) | processo de glicoconjugação | |
| AR095496A1 (es) | Formulaciones de anticuerpos anti-receptor de prolactina | |
| EA202090675A3 (ru) | Стабилизированные растворимые f-полипептиды rsv до слияния | |
| AR092401A1 (es) | Formulaciones de anticuerpos anti-receptor de prolactina (anti-prlr) | |
| BR112015030326A2 (pt) | Agonistas ultrapuros de guanilato ciclase c, método de fabricar e usar os mesmos | |
| CL2012001336A1 (es) | Composicion farmaceutica solida de daptomicina preparada por liofilizacion de una solucion acuosa que comprende daptomicina y al menos un excipiente seleccionado de glicina y un azucar no reductor con un ph de 6,5-7,5; producto farmaceutico; metodo de fabricacion; uso para tratar infecciones bacterianas. | |
| GB2499479A (en) | Stabilisation of viral particles | |
| CL2014003012A1 (es) | Formulación en capsulas que comprende al menos un compuesto de formula (i), solubilizado; metodo de administracion de la formulacion; uso para tratar una infeccion por el virus de la hepatitis c. | |
| BR112017017747A2 (pt) | processo de preparação de um extrato de matriz vegetal com um composto anfifílico não iônico como adjuvante de extração em meio aquoso | |
| EA201990163A1 (ru) | Консервация микроорганизмов | |
| HK1217295A1 (zh) | 4'-疊氮基，3'-脫氧基-3'-氟取代的核苷衍生物 | |
| UY35848A (es) | Tienopirimidinas | |
| BR112015028824A2 (pt) | composição de tensoativo concentrada | |
| WO2016038521A8 (en) | Pharmaceutical compositions of liraglutide | |
| BR112018070084A2 (pt) | composições de célula viável, e métodos relacionados às mesmas | |
| MX387019B (es) | Formulacion farmaceutica parenteral que contiene acido carglumico. | |
| BR112015013071A8 (pt) | solução de trombina aquosa, seus métodos para liofilização e composição de trombina sólida | |
| EA201500942A1 (ru) | ПРОТИВОВИРУСНЫЙ ИНДОЛО[2,3-b]ХИНОКСАЛИН |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |