AR078230A1 - Metodo para la preparacion de 1-amino-1,3,3,5,5-pentametilciclohexano - Google Patents

Metodo para la preparacion de 1-amino-1,3,3,5,5-pentametilciclohexano

Info

Publication number
AR078230A1
AR078230A1 ARP100102317A ARP100102317A AR078230A1 AR 078230 A1 AR078230 A1 AR 078230A1 AR P100102317 A ARP100102317 A AR P100102317A AR P100102317 A ARP100102317 A AR P100102317A AR 078230 A1 AR078230 A1 AR 078230A1
Authority
AR
Argentina
Prior art keywords
amino
pentametilciclohexano
preparation
pentamethylcyclohexane
neramexane
Prior art date
Application number
ARP100102317A
Other languages
English (en)
Original Assignee
Merz Pharma Gmbh & Co Kgaa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merz Pharma Gmbh & Co Kgaa filed Critical Merz Pharma Gmbh & Co Kgaa
Publication of AR078230A1 publication Critical patent/AR078230A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/54—Preparation of compounds containing amino groups bound to a carbon skeleton by rearrangement reactions
    • C07C209/58—Preparation of compounds containing amino groups bound to a carbon skeleton by rearrangement reactions from or via amides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Abstract

La solicitud se refiere a un método para la produccion de 1-amino-1,3,3,5,5-pentametilciclohexano (Neramexane) o una sal farmacéuticamente aceptable del mismo que comprende la etapa de calentamiento de una mezcla que comprende 1-cloroacetamido-1,3,3,5,5-pentametilciclohexano, tiourea y agua.
ARP100102317A 2009-06-29 2010-06-29 Metodo para la preparacion de 1-amino-1,3,3,5,5-pentametilciclohexano AR078230A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US26978209P 2009-06-29 2009-06-29
EP09008465 2009-06-29

Publications (1)

Publication Number Publication Date
AR078230A1 true AR078230A1 (es) 2011-10-26

Family

ID=41103489

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP100102317A AR078230A1 (es) 2009-06-29 2010-06-29 Metodo para la preparacion de 1-amino-1,3,3,5,5-pentametilciclohexano

Country Status (12)

Country Link
US (1) US20120130131A1 (es)
EP (1) EP2448909B1 (es)
JP (1) JP5599878B2 (es)
AR (1) AR078230A1 (es)
CA (1) CA2765611A1 (es)
DK (1) DK2448909T3 (es)
ES (1) ES2416071T3 (es)
HR (1) HRP20130485T1 (es)
PL (1) PL2448909T3 (es)
SI (1) SI2448909T1 (es)
TW (1) TW201107274A (es)
WO (1) WO2011000541A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2448911A1 (en) 2009-06-29 2012-05-09 Merz Pharma GmbH & Co. KGaA Method of preparing 1-chloroacetamido-1,3,3,5,5-pentamethylcyclohexane

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5930028B2 (ja) * 1978-11-25 1984-07-24 キヤノン株式会社 無鉄心回転電機のコイル巻回方式
JPS58131944A (ja) * 1982-01-29 1983-08-06 Toyo Soda Mfg Co Ltd アニリン誘導体の製造法
DE10128331A1 (de) * 2001-06-12 2002-12-19 Aventis Pharma Gmbh Anthranilsäureamide mit Heteroarylsulfonyl-Seitenkette, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltende pharmazeutische Zubereitungen
EP2397122B1 (en) * 2004-06-17 2014-05-14 Merz Pharma GmbH & Co. KGaA Formulations of neramexane dosage forms
FR2876689B1 (fr) * 2004-10-14 2008-02-22 Aventis Pharma Sa Nouveau procede et intermediaires de preparation de derives de n-(1-benzhydryl-azetidin-3-yl)-n-phenyl-methylsulfonamide
FR2888849B1 (fr) * 2005-07-19 2007-10-05 Pierre Fabre Medicament Sa Procede de preparation de la 4b-amino-4'-demethyl-4-desoxypodophyllotoxine
US20070141148A1 (en) * 2005-11-30 2007-06-21 Merz Pharma Gmbh & Co. Kgaa Neramexane MR matrix tablet
PL1820792T3 (pl) * 2006-02-21 2012-06-29 Hexal Ag Sposób otrzymywania adamantanoamin

Also Published As

Publication number Publication date
EP2448909B1 (en) 2013-05-01
PL2448909T3 (pl) 2013-09-30
US20120130131A1 (en) 2012-05-24
TW201107274A (en) 2011-03-01
WO2011000541A1 (en) 2011-01-06
HRP20130485T1 (en) 2013-06-30
EP2448909A1 (en) 2012-05-09
JP5599878B2 (ja) 2014-10-01
WO2011000541A8 (en) 2011-09-01
SI2448909T1 (sl) 2013-07-31
JP2012531390A (ja) 2012-12-10
CA2765611A1 (en) 2011-01-06
DK2448909T3 (da) 2013-07-15
ES2416071T3 (es) 2013-07-30

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