AR077523A1 - Procedimiento para aislar tigeciclina y tigeciclina elaborada a partir del procedimiento - Google Patents
Procedimiento para aislar tigeciclina y tigeciclina elaborada a partir del procedimientoInfo
- Publication number
- AR077523A1 AR077523A1 ARP100100147A ARP100100147A AR077523A1 AR 077523 A1 AR077523 A1 AR 077523A1 AR P100100147 A ARP100100147 A AR P100100147A AR P100100147 A ARP100100147 A AR P100100147A AR 077523 A1 AR077523 A1 AR 077523A1
- Authority
- AR
- Argentina
- Prior art keywords
- procedure
- tigecicline
- isolating
- elaborated
- tigecycline
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/22—Separation; Purification; Stabilisation; Use of additives
- C07C231/24—Separation; Purification
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/65—Tetracyclines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/24—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring of the carbon skeleton
- C07C237/26—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring of the carbon skeleton of a ring being part of a condensed ring system formed by at least four rings, e.g. tetracycline
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/02—Ortho- or ortho- and peri-condensed systems
- C07C2603/40—Ortho- or ortho- and peri-condensed systems containing four condensed rings
- C07C2603/42—Ortho- or ortho- and peri-condensed systems containing four condensed rings containing only six-membered rings
- C07C2603/44—Naphthacenes; Hydrogenated naphthacenes
- C07C2603/46—1,4,4a,5,5a,6,11,12a- Octahydronaphthacenes, e.g. tetracyclines
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Peptides Or Proteins (AREA)
Abstract
La presente provee un procedimiento para aislar tigeciclina, procedimiento que comprende el paso de secar por rociado una solucion de tigeciclina en un solvente. Con preferencia, el solvente es agua o un solvente orgánico. En otro aspecto, se provee tigeciclina que se puede obtener por secado por rociado, particularmente en una forma amorfa. En particular, la solicitud provee tigeciclina que se puede obtener por secado por rociado de acuerdo con el procedimiento de la solicitud.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PT104350A PT104350A (pt) | 2009-01-23 | 2009-01-23 | Processo de isolamento de tigeciclina |
Publications (1)
Publication Number | Publication Date |
---|---|
AR077523A1 true AR077523A1 (es) | 2011-09-07 |
Family
ID=42244097
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP100100147A AR077523A1 (es) | 2009-01-23 | 2010-01-22 | Procedimiento para aislar tigeciclina y tigeciclina elaborada a partir del procedimiento |
Country Status (11)
Country | Link |
---|---|
US (1) | US9187410B2 (es) |
EP (1) | EP2382183A2 (es) |
JP (2) | JP2012515753A (es) |
KR (1) | KR20110111494A (es) |
CN (1) | CN102361850A (es) |
AR (1) | AR077523A1 (es) |
CA (1) | CA2749981A1 (es) |
IL (1) | IL214219A0 (es) |
PT (1) | PT104350A (es) |
TW (1) | TW201038276A (es) |
WO (1) | WO2010084325A2 (es) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103091424B (zh) * | 2013-01-31 | 2014-11-19 | 成都百裕科技制药有限公司 | 替加环素中杂质的检测方法 |
CN104418766B (zh) * | 2013-08-26 | 2018-09-07 | 江苏豪森药业集团有限公司 | 替加环素的纯化方法 |
CN108602847A (zh) * | 2015-12-18 | 2018-09-28 | 格莱克特生物技术公司 | 多晶型及方法 |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5494903A (en) | 1991-10-04 | 1996-02-27 | American Cyanamid Company | 7-substituted-9-substituted amino-6-demethyl-6-deoxytetracyclines |
US5675030A (en) | 1994-11-16 | 1997-10-07 | American Cyanamid Company | Method for selective extracting a 7-(hydrogen or substituted amino)-9- (substituted glycyl) amido!-6-demethyl-6-deoxytetracycline compound |
IL116085A (en) * | 1994-12-16 | 1999-12-31 | Ortho Pharma Corp | Spray dried erythropoietin |
US7927613B2 (en) * | 2002-02-15 | 2011-04-19 | University Of South Florida | Pharmaceutical co-crystal compositions |
US7790905B2 (en) * | 2002-02-15 | 2010-09-07 | Mcneil-Ppc, Inc. | Pharmaceutical propylene glycol solvate compositions |
CL2004001884A1 (es) * | 2003-08-04 | 2005-06-03 | Pfizer Prod Inc | Procedimiento de secado por pulverizacion para la formacion de dispersiones solidas amorfas de un farmaco y polimeros. |
WO2005089738A2 (en) * | 2004-03-17 | 2005-09-29 | Mpex Pharmaceuticals, Inc. | Use and administration of bacterial efflux pump inhibitors |
AR057649A1 (es) | 2005-05-27 | 2007-12-12 | Wyeth Corp | Formas solidas cristalinas de tigeciclina y metodos para preparar las mismas |
AR055336A1 (es) | 2005-06-16 | 2007-08-22 | Wyeth Corp | Proeso de elaboracion para la produccion de tigeciclina como un polvo reconstituible, polvo de tigeciclina liofilizado y producto hecho mediante el proceso |
US8263645B2 (en) * | 2006-02-03 | 2012-09-11 | Pari Pharma Gmbh | Disodium cromoglycate compositions and methods for administering same |
IN2015DN00888A (es) * | 2006-02-22 | 2015-07-10 | Mannkind Corp | |
WO2007126609A1 (en) * | 2006-03-29 | 2007-11-08 | Nitromed, Inc. | Nitric oxide enhancing prostaglandin compounds, compositions and methods of use |
PL2016045T3 (pl) | 2006-04-24 | 2015-04-30 | Teva Pharma | Krystaliczna postać tygecykliny i sposoby jej otrzymywania |
US8198469B2 (en) * | 2006-11-29 | 2012-06-12 | Teva Pharmaceutical Industries Ltd. | Crystalline forms of tigecycline and processes for preparation thereof |
PT103661B (pt) * | 2007-02-23 | 2010-09-07 | Hovione Farmaciencia S A | Processo de preparação de minociclina base cristalina |
US20110124893A1 (en) * | 2008-01-23 | 2011-05-26 | Sandoz Ag | Antibiotic compounds |
ITMI20080807A1 (it) | 2008-05-05 | 2009-11-06 | Antibioticos Spa | Procedimento per la preparazione di tigeciclina in forma amorfa |
JP2010095454A (ja) * | 2008-10-14 | 2010-04-30 | Cyclochem:Kk | 抗菌組成物 |
PT105116B (pt) * | 2010-05-14 | 2012-10-16 | Hovione Farmaciencia S A | Novas partículas de tetraciclina e agente protector. |
US8529914B2 (en) * | 2010-06-28 | 2013-09-10 | Richard C. Fuisz | Bioactive dose having containing a material for modulating pH of a bodily fluid to help or hinder absorption of a bioactive |
-
2009
- 2009-01-23 PT PT104350A patent/PT104350A/pt unknown
-
2010
- 2010-01-22 CN CN2010800053526A patent/CN102361850A/zh active Pending
- 2010-01-22 JP JP2011546941A patent/JP2012515753A/ja not_active Withdrawn
- 2010-01-22 EP EP10702330A patent/EP2382183A2/en not_active Withdrawn
- 2010-01-22 CA CA2749981A patent/CA2749981A1/en not_active Abandoned
- 2010-01-22 US US13/145,445 patent/US9187410B2/en not_active Expired - Fee Related
- 2010-01-22 KR KR1020117019428A patent/KR20110111494A/ko not_active Application Discontinuation
- 2010-01-22 AR ARP100100147A patent/AR077523A1/es unknown
- 2010-01-22 TW TW099101874A patent/TW201038276A/zh unknown
- 2010-01-22 WO PCT/GB2010/000104 patent/WO2010084325A2/en active Application Filing
-
2011
- 2011-07-20 IL IL214219A patent/IL214219A0/en unknown
-
2015
- 2015-03-10 JP JP2015046841A patent/JP2015166347A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
US20120028928A1 (en) | 2012-02-02 |
EP2382183A2 (en) | 2011-11-02 |
IL214219A0 (en) | 2011-08-31 |
JP2012515753A (ja) | 2012-07-12 |
CA2749981A1 (en) | 2010-07-29 |
US9187410B2 (en) | 2015-11-17 |
JP2015166347A (ja) | 2015-09-24 |
TW201038276A (en) | 2010-11-01 |
CN102361850A (zh) | 2012-02-22 |
WO2010084325A3 (en) | 2010-09-23 |
PT104350A (pt) | 2010-07-23 |
KR20110111494A (ko) | 2011-10-11 |
WO2010084325A2 (en) | 2010-07-29 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CL2013003254A1 (es) | Un articulo para fumar, que comprende un sistema de liberacion de aditivo, que comprende un componente de liberacion de aditivo y una estructura de soporte configurada para recibir y retener en su interior el componente de liberacion de aditivo; y metodo para fabricar dicho articulo para fumar. | |
BR112013003133A2 (pt) | processo para o tratamento de uma solução aquosa, e, instalação para o tratamento de uma solução aquosa | |
BR112013033490A2 (pt) | processo de tratamento de um célula fotovoltaica com heterojunção | |
BR112013032028A2 (pt) | processo para produção de grafeno | |
GT201200293A (es) | Marcadores predictivos útiles en el tratamiento del síndrome frágil x (fxs) | |
BR112013029736A2 (pt) | arruela de olhal porta três cabos | |
AR093986A1 (es) | Cuerpos de carbono ferromagneticos y proceso de produccion | |
CL2013002531A1 (es) | Metodo para reducir un enlace c-o al enlace c-h por un sustrato utilizando un donante de hidrogeno, un catalizador de metal y una base en una mezcla de disolventes que comprende al menos dos disolventes en donde uno es agua. | |
CL2014000636A1 (es) | Composicion detergente enzimatica que comprende la combinacion de un sistema tensioactivo, una o mas enzimas y uno o mas compuestos de lignina; y procedimiento para el tratamiento de un sustrato. | |
GT201300256A (es) | Procesos para la elaboración de depsipéptidos macrocíclicos y nuevos intermediarios | |
CL2013003823A1 (es) | Procedimiento para revestir una superficie con micelas que comprenden un copolímero de bloque ab donde se expone la superficie con un líquido apolar que contiene las micelas y donde la superficie es un cristal agroquímico orgánico. | |
CL2014003055A1 (es) | Procedimiento para preparar una composicion farmaceutica que comprende i) proporcionar una primera combinacion que comprende un compuesto inhibidor del proteasoma peptidico, una o mas ciclodextrinas y agua, y ii) poner en contacto la primera combinacion con un acido para formar una segunda combinacion; composicion farmaceutica. | |
CL2013002819A1 (es) | Proceso para producir un polimero acilado que contine vinilamina y su aplicacion como aditivo en la fabricacion de papel. | |
BR112014017308A2 (pt) | processo para a digestão anaeróbica de uma solução substancialmente aquosa | |
AR088850A1 (es) | Catalizador de hidropirolisis y proceso de conversion de biomasa | |
BR112014003140A2 (pt) | catalisador de complexo á base de rutênio e processo de hidrogenação de substratos que possuem pelo menos uma dupla ligação carbono-carbono | |
CL2013000683A1 (es) | Metodo para la eliminacion de productos quimicos organicos y complejos organometalicos del agua de proceso que contiene dietilentriamina (deta) que comprende contactar dicha agua de proceso con zeolitas; y metodo para controlar los niveles de deta en el area de relaves de una planta de procesamiento de minerales. | |
BRPI0913906A2 (pt) | processo para produzir ácido orgânico | |
AR077523A1 (es) | Procedimiento para aislar tigeciclina y tigeciclina elaborada a partir del procedimiento | |
SMT201600042B (it) | Capsula con apertura controllata, processo e dispositivo per il funzionamento della capsula | |
AR110966A2 (es) | Método para formar una lente mediante procesamiento de un gas en un entorno de fase de vapor | |
CO6470817A2 (es) | Cristales de solvato novedosos | |
CL2015000957A1 (es) | Métodos para reducir la formación de encrustante | |
CL2015001384A1 (es) | Aparato y método para el tratamiento de agua principalmente por la sustitución usando un campo eléctrico dinámico | |
BR112014026433A2 (pt) | composição detergente líquida aquosa estruturada, composição de alta formação de espuma e processo para fabricar um líquido detergente estruturado com fibra de maçã sem polpa |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FB | Suspension of granting procedure |