AR075586A1 - Proceso, purificacion y cristalizacion de 1-(4-{[4-(dimetilamino)piperidin-1-il]carbonil}fenil)-3-[4-(4,6-dimorfolin-4-il-1,3,5-triazin-2-il)fenil]urea, inhibidor de pi3k/mtor - Google Patents

Proceso, purificacion y cristalizacion de 1-(4-{[4-(dimetilamino)piperidin-1-il]carbonil}fenil)-3-[4-(4,6-dimorfolin-4-il-1,3,5-triazin-2-il)fenil]urea, inhibidor de pi3k/mtor

Info

Publication number
AR075586A1
AR075586A1 ARP100100519A ARP100100519A AR075586A1 AR 075586 A1 AR075586 A1 AR 075586A1 AR P100100519 A ARP100100519 A AR P100100519A AR P100100519 A ARP100100519 A AR P100100519A AR 075586 A1 AR075586 A1 AR 075586A1
Authority
AR
Argentina
Prior art keywords
alkyl
heterocyclyl
optionally substituted
heteroaryl
amino
Prior art date
Application number
ARP100100519A
Other languages
English (en)
Spanish (es)
Inventor
John Richard Potoski
Gulnaz Khafizova
Original Assignee
Wyeth Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Llc filed Critical Wyeth Llc
Publication of AR075586A1 publication Critical patent/AR075586A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ARP100100519A 2009-02-23 2010-02-23 Proceso, purificacion y cristalizacion de 1-(4-{[4-(dimetilamino)piperidin-1-il]carbonil}fenil)-3-[4-(4,6-dimorfolin-4-il-1,3,5-triazin-2-il)fenil]urea, inhibidor de pi3k/mtor AR075586A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US15456209P 2009-02-23 2009-02-23

Publications (1)

Publication Number Publication Date
AR075586A1 true AR075586A1 (es) 2011-04-20

Family

ID=42104374

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP100100519A AR075586A1 (es) 2009-02-23 2010-02-23 Proceso, purificacion y cristalizacion de 1-(4-{[4-(dimetilamino)piperidin-1-il]carbonil}fenil)-3-[4-(4,6-dimorfolin-4-il-1,3,5-triazin-2-il)fenil]urea, inhibidor de pi3k/mtor

Country Status (3)

Country Link
JP (1) JP2010215620A (fr)
AR (1) AR075586A1 (fr)
WO (1) WO2010096619A1 (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102250065B (zh) * 2011-05-20 2015-05-13 浙江海正药业股份有限公司 取代的三嗪苯脲衍生物及其用途
CN103917530B (zh) 2011-09-21 2016-08-24 塞尔佐姆有限公司 作为mtor抑制剂的吗啉代取代的脲或氨基甲酸衍生物
MX341577B (es) 2011-10-07 2016-08-25 Cellzome Ltd Derivados biciclicos de pirimidin-urea o carbamato sustituidos con morfolino como inhibidores del blanco de rapamicina de mamifero.
SG11201703826TA (en) 2014-12-17 2017-07-28 Pfizer Formulations of a pi3k/mtor-inhibitor for intravenous administration
RS62663B1 (sr) * 2017-08-25 2021-12-31 Pfizer Farmaceutska vodena formulacija koja sadrži 1-(4-{[4-(dimetilamino)piperidin-1-il]karbonil}fenil)-3-[4-(4,6-dimorfolin-4-il-1,3,5-triazin-2-il)fenil]ureu
FI3810089T3 (fi) 2018-06-07 2023-09-22 Pfizer Vesipitoinen formulaatio, joka käsittää 1-(4-{[4-(dimetyyliamino)piperidin-1-yyli]karbonyyli}fenyyli)-3-[4-(4,6-dimorfolin-4-yyli-1,3,5-triatsin-2-yyli)fenyyli]ureaa
US20230150970A1 (en) * 2020-03-27 2023-05-18 Dong-A St Co., Ltd. Aminopyrimidine derivatives and their use as aryl hydrocarbon receptor modulators

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100563514B1 (ko) * 1997-07-24 2006-03-27 젠야쿠코교가부시키가이샤 헤테로고리 화합물 및 이를 유효성분으로 하는 항종양제
PT2294072T (pt) 2008-05-23 2017-05-29 Wyeth Llc Compostos de triazina como inibidores de p13 quinase e mtor

Also Published As

Publication number Publication date
WO2010096619A1 (fr) 2010-08-26
JP2010215620A (ja) 2010-09-30

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