AR068822A1 - Composiciones farmaceuticas liofilizadas que comprenden n-hidroxi-3-[4-[[[2-(2-metil-1h-indol-3-il)etil]amino]metil]fenil]-2e-2-propenamida, torta farmaceutica, proceso - Google Patents
Composiciones farmaceuticas liofilizadas que comprenden n-hidroxi-3-[4-[[[2-(2-metil-1h-indol-3-il)etil]amino]metil]fenil]-2e-2-propenamida, torta farmaceutica, procesoInfo
- Publication number
- AR068822A1 AR068822A1 ARP080104055A ARP080104055A AR068822A1 AR 068822 A1 AR068822 A1 AR 068822A1 AR P080104055 A ARP080104055 A AR P080104055A AR P080104055 A ARP080104055 A AR P080104055A AR 068822 A1 AR068822 A1 AR 068822A1
- Authority
- AR
- Argentina
- Prior art keywords
- methyl
- pharmaceutical
- propenamide
- indol
- phenyl
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A61K31/4045—Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Reivindicacion 1: Una composicion farmacéutica, la cual comprende: (a) N-hidroxi-3-[4-[[[(2-(2-metil-1H-indol-3-il)-etil]-amino]-metil]-fenil]-2E-2-propenamida, o una sal farmacéuticamente aceptable de la misma; (b) un regulador del pH o un componente regulador del pH; (c) un agente de volumen. Reivindicacion 2: La composicion de la reivindicacion 1, la cual comprende además un quelante/antioxidante. Reivindicacion 3: La composicion de la reivindicacion 1, en donde el agente de volumen mencionado se selecciona a partir de sacarosa, trehalosa, dextrano, y HPbCD. Reivindicacion 4: La composicion de la reivindicacion 2, en donde el quelante/antioxidante mencionado es EDTA disodica.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US97383007P | 2007-09-20 | 2007-09-20 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR068822A1 true AR068822A1 (es) | 2009-12-09 |
Family
ID=40005335
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP080104055A AR068822A1 (es) | 2007-09-20 | 2008-09-18 | Composiciones farmaceuticas liofilizadas que comprenden n-hidroxi-3-[4-[[[2-(2-metil-1h-indol-3-il)etil]amino]metil]fenil]-2e-2-propenamida, torta farmaceutica, proceso |
Country Status (20)
Country | Link |
---|---|
US (1) | US20100331387A1 (es) |
EP (1) | EP2205222A1 (es) |
JP (1) | JP2010540445A (es) |
KR (1) | KR20100059887A (es) |
CN (1) | CN101801345A (es) |
AR (1) | AR068822A1 (es) |
AU (1) | AU2008302273A1 (es) |
BR (1) | BRPI0817118A2 (es) |
CA (1) | CA2696914A1 (es) |
CL (1) | CL2008002786A1 (es) |
CO (1) | CO6270207A2 (es) |
EC (1) | ECSP10010039A (es) |
GT (1) | GT201000062A (es) |
MA (1) | MA31744B1 (es) |
MX (1) | MX2010002970A (es) |
PE (1) | PE20090706A1 (es) |
RU (1) | RU2010115262A (es) |
TN (1) | TN2010000097A1 (es) |
TW (1) | TW200930416A (es) |
WO (1) | WO2009039226A1 (es) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2017167837A1 (en) * | 2016-03-31 | 2017-10-05 | Midatech Ltd. | Cyclodextrin-panobinostat adduct |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PE20020354A1 (es) * | 2000-09-01 | 2002-06-12 | Novartis Ag | Compuestos de hidroxamato como inhibidores de histona-desacetilasa (hda) |
US7250514B1 (en) * | 2002-10-21 | 2007-07-31 | Takeda San Diego, Inc. | Histone deacetylase inhibitors |
ME00294B (me) * | 2003-07-23 | 2011-05-10 | Bayer Pharmaceuticals Corp | Fluoro supstituisana omega-karaboksiaril difenil urea za liječenje i prevenciju bolesti i stanja bolesti |
WO2005013958A1 (en) * | 2003-08-07 | 2005-02-17 | Novartis Ag | Histone deacetylase inhibitors as immunosuppressants |
PE20060664A1 (es) * | 2004-09-15 | 2006-08-04 | Novartis Ag | Amidas biciclicas como inhibidores de cinasa |
US20060128660A1 (en) * | 2004-12-10 | 2006-06-15 | Wisconsin Alumni Research Foundation | FK228 analogs and methods of making and using the same |
WO2006094068A2 (en) * | 2005-03-01 | 2006-09-08 | The Regents Of The University Of Michigan | Hdac inhibitors that promote brm expression and brm related diagnostics |
CA2674604A1 (en) * | 2007-01-10 | 2008-07-17 | Novartis Ag | Formulations of deacetylase inhibitors |
MX2009008584A (es) * | 2007-02-15 | 2009-08-18 | Novartis Ag | Combinacion de lbh589 con otros agentes terapeuticos para el tratamiento de cancer. |
-
2008
- 2008-09-17 CL CL2008002786A patent/CL2008002786A1/es unknown
- 2008-09-18 PE PE2008001634A patent/PE20090706A1/es not_active Application Discontinuation
- 2008-09-18 CN CN200880107798A patent/CN101801345A/zh active Pending
- 2008-09-18 US US12/676,755 patent/US20100331387A1/en not_active Abandoned
- 2008-09-18 RU RU2010115262/15A patent/RU2010115262A/ru unknown
- 2008-09-18 BR BRPI0817118A patent/BRPI0817118A2/pt not_active IP Right Cessation
- 2008-09-18 MX MX2010002970A patent/MX2010002970A/es not_active Application Discontinuation
- 2008-09-18 AR ARP080104055A patent/AR068822A1/es unknown
- 2008-09-18 CA CA2696914A patent/CA2696914A1/en not_active Abandoned
- 2008-09-18 WO PCT/US2008/076752 patent/WO2009039226A1/en active Application Filing
- 2008-09-18 JP JP2010525936A patent/JP2010540445A/ja active Pending
- 2008-09-18 KR KR1020107006075A patent/KR20100059887A/ko not_active Application Discontinuation
- 2008-09-18 EP EP08832517A patent/EP2205222A1/en not_active Withdrawn
- 2008-09-18 AU AU2008302273A patent/AU2008302273A1/en not_active Abandoned
- 2008-09-19 TW TW097136190A patent/TW200930416A/zh unknown
-
2010
- 2010-02-25 TN TNP2010000097A patent/TN2010000097A1/fr unknown
- 2010-03-12 MA MA32691A patent/MA31744B1/fr unknown
- 2010-03-16 GT GT201000062A patent/GT201000062A/es unknown
- 2010-03-17 EC EC2010010039A patent/ECSP10010039A/es unknown
- 2010-03-25 CO CO10035474A patent/CO6270207A2/es not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
CL2008002786A1 (es) | 2009-05-15 |
CA2696914A1 (en) | 2009-03-26 |
CN101801345A (zh) | 2010-08-11 |
KR20100059887A (ko) | 2010-06-04 |
TW200930416A (en) | 2009-07-16 |
JP2010540445A (ja) | 2010-12-24 |
RU2010115262A (ru) | 2011-10-27 |
MX2010002970A (es) | 2010-04-01 |
US20100331387A1 (en) | 2010-12-30 |
MA31744B1 (fr) | 2010-10-01 |
ECSP10010039A (es) | 2010-04-30 |
PE20090706A1 (es) | 2009-07-15 |
CO6270207A2 (es) | 2011-04-20 |
WO2009039226A1 (en) | 2009-03-26 |
GT201000062A (es) | 2012-03-30 |
EP2205222A1 (en) | 2010-07-14 |
AU2008302273A1 (en) | 2009-03-26 |
TN2010000097A1 (en) | 2011-09-26 |
BRPI0817118A2 (pt) | 2019-09-24 |
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