AR065723A1 - Composicion anestesica nanoparticulada para la administracion topica - Google Patents

Composicion anestesica nanoparticulada para la administracion topica

Info

Publication number
AR065723A1
AR065723A1 ARP080101035A ARP080101035A AR065723A1 AR 065723 A1 AR065723 A1 AR 065723A1 AR P080101035 A ARP080101035 A AR P080101035A AR P080101035 A ARP080101035 A AR P080101035A AR 065723 A1 AR065723 A1 AR 065723A1
Authority
AR
Argentina
Prior art keywords
poly
anesthetic composition
topical administration
anesthetic
amino
Prior art date
Application number
ARP080101035A
Other languages
English (en)
Original Assignee
Universidadefed Do Rio Grande
Biolab Sanus Farmaceutica Ltda
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39765309&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR065723(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Universidadefed Do Rio Grande, Biolab Sanus Farmaceutica Ltda filed Critical Universidadefed Do Rio Grande
Publication of AR065723A1 publication Critical patent/AR065723A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/166—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5138—Organic macromolecular compounds; Dendrimers obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5146—Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
    • A61K9/5153—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A61P23/02—Local anaesthetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nanotechnology (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Dermatology (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Uso de dichas nanopartículas poliméricas que comprenden por lo menos un agente anestésico local, en la preparacion de una composicion anestésica para la administracion topica sobre la piel o mucosas. Reivindicacion 1: Composicion anestésica para laadministracion topica sobre la piel o mucosas caracterizada porque comprende por lo menos un agente anestésico local en nanopartículas poliméricas en una cantidad terapéuticamente eficaz y por lo menos un agente que aumenta la viscosidad. Reivindicacion 2: La composicion anestésica, de acuerdo con la reivindicacion 1, caracterizada porque los polímeros utilizados en la produccion de las nanopartículas pueden ser seleccionados del grupo constituido por: poli (?-caprolactona);copolímeros del ácido metacrílico y de ésteres acrílicos o metacrílicos; poli (metacrilato de alquilo); poli (metacrilato de metilo), poli (láctico), poli (láctico-glicolico), poli (glicolico), poli (caprolactona), poli (amidas), poli (anhídridos),poli (aminoácidos), poli (ésteres), poli (cianoacrilatos), poli (fosfacenos), poli (fosfoésteres), poli (esteramidas), poli (dioxanonas), poli (acetales), poli (cetales), poli (carbonatos), poli (ortocarbonatos), poli (uretanos) degradables,quitinas, quitosana, poli (hidroxibutiratos), poli (hidroxivaleratos), poli (ácido málico), poli (alquilenooxalatos), poli (alquilenosuccinatos), poli (hidroxibutiratos-co-hidroxivaleratos), y copolímeros terpolímeros, celulosa oxidada, ocombinaciones o mezclas de estos materiales. Reivindicacion 3: La composicion anestésica, de acuerdo con la reivindicacion 1 o 2, caracterizada porque los agentes anestésicos locales se pueden seleccionar del grupo que consiste en: éster debenzoato o amino-éster, anilida amino-amida, naftoato amino-éster, ácido benzoico, pramoxina, diclonina, mexiletina, lidocaína, prilocaína, bupivacaína, mepivocaína, etidocaína, butanilcaína, trimecaína, tetracaína, benzocaína, ropivacaína,dibucaína, procaína, clorprocaína, butambeno, picrato, dibucaína, articaína e xilocaína, y sus sales, derivados o mezclas.
ARP080101035A 2007-03-16 2008-03-13 Composicion anestesica nanoparticulada para la administracion topica AR065723A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
BRPI0700832A BRPI0700832B8 (pt) 2007-03-16 2007-03-16 composição anestésica tópica compreendendo suspensão de nanocápsulas poliméricas de lidocaína e prilocaína

Publications (1)

Publication Number Publication Date
AR065723A1 true AR065723A1 (es) 2009-06-24

Family

ID=39765309

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP080101035A AR065723A1 (es) 2007-03-16 2008-03-13 Composicion anestesica nanoparticulada para la administracion topica

Country Status (15)

Country Link
US (1) US8568788B2 (es)
EP (1) EP2134334B1 (es)
JP (1) JP5496684B2 (es)
AR (1) AR065723A1 (es)
BR (1) BRPI0700832B8 (es)
CL (1) CL2008000728A1 (es)
CO (1) CO6220944A2 (es)
EC (1) ECSP099691A (es)
ES (1) ES2804466T3 (es)
HU (1) HUE051155T2 (es)
MX (1) MX2009009853A (es)
PE (2) PE20131337A1 (es)
PL (1) PL2134334T3 (es)
PT (1) PT2134334T (es)
WO (1) WO2008113144A1 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0913809B1 (pt) 2008-10-02 2019-02-05 Mylan Inc método para produzir continuamente um laminado adesivo sensível á pressão multicamada
BR102012022036B1 (pt) * 2012-08-31 2019-10-01 Biolab Sanus Farmacêutica Ltda. Nanopartícula polimérica de finasterida e minoxidil, processo de sua preparação, suspensão aquosa contendo a mesma, composição farmacêutica, e seu uso
BR102014028009B1 (pt) 2014-11-10 2023-04-18 Universidade Federal De Pelotas Composições filmogênicas para bioadesivos anestésicos tópicos (bats) para liberação controlada de princípios ativos e bioadesivos anestésicos tópicos
US11452700B2 (en) 2017-08-04 2022-09-27 Eric Haas Method of delivering an anesthetic agent and glucocorticoid micro and nano bioerodible particles
CN113244167B (zh) * 2021-05-20 2022-11-29 河北科技大学 一种盐酸利多卡因凝胶及其制备方法
RU208882U1 (ru) * 2021-08-25 2022-01-19 Федеральное государственное бюджетное образовательное учреждение высшего образования "Курская государственная сельскохозяйственная академия имени И.И. Иванова" Раневая атравматическая повязка для животных

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE7713618L (sv) * 1977-12-01 1979-06-02 Astra Laekemedel Ab Lokalanestetisk blandning
FR2659554B1 (fr) * 1990-03-16 1994-09-30 Oreal Composition pour le traitement cosmetique et/ou pharmaceutique des couches superieures de l'epiderme par application topique sur la peau et procede de preparation correspondant.
DE4120760A1 (de) * 1991-06-24 1993-03-04 3 M Medica Gmbh Traegersysteme fuer arzneimittel
JPH09255565A (ja) * 1996-03-26 1997-09-30 Daikyo Yakuhin Kogyo Kk 皮膚局所麻酔用ヒドロゲルパッチ
US6248345B1 (en) 1997-07-02 2001-06-19 Euro-Celtique, S.A. Prolonged anesthesia in joints and body spaces
US5993836A (en) * 1998-04-28 1999-11-30 Castillo; James G. Topical anesthetic formulation
KR100463167B1 (ko) * 2001-04-13 2004-12-23 주식회사 태평양 고분자 나노입자를 이용한 경피흡수제 및 이를 함유한외용제 조성물
US20070154527A1 (en) * 2001-10-12 2007-07-05 Monosoirx, Llc Topical film compositions for delivery of actives
WO2006002365A2 (en) * 2004-06-24 2006-01-05 Angiotech International Ag Microparticles with high loadings of a bioactive agent
WO2006047279A2 (en) * 2004-10-21 2006-05-04 University Of Iowa Research Foundation In situ controlled release drug delivery system
WO2006091719A2 (en) * 2005-02-23 2006-08-31 Sontra Medical Corporation Compositions and methods enhancing transdermal delivery of drugs and biologics

Also Published As

Publication number Publication date
BRPI0700832B8 (pt) 2021-05-25
US8568788B2 (en) 2013-10-29
EP2134334A1 (en) 2009-12-23
CL2008000728A1 (es) 2008-09-26
EP2134334A4 (en) 2013-04-24
CO6220944A2 (es) 2010-11-19
ES2804466T3 (es) 2021-02-08
ECSP099691A (es) 2010-02-26
BRPI0700832B1 (pt) 2017-12-26
EP2134334B1 (en) 2020-05-13
PT2134334T (pt) 2020-08-20
MX2009009853A (es) 2010-02-18
BRPI0700832A (pt) 2008-11-04
PE20081883A1 (es) 2008-12-27
JP2010521498A (ja) 2010-06-24
PE20131337A1 (es) 2013-11-18
JP5496684B2 (ja) 2014-05-21
HUE051155T2 (hu) 2021-03-01
WO2008113144A1 (en) 2008-09-25
US20100086614A1 (en) 2010-04-08
PL2134334T3 (pl) 2021-03-08

Similar Documents

Publication Publication Date Title
AR065723A1 (es) Composicion anestesica nanoparticulada para la administracion topica
JP2007217431A5 (es)
AR063621A1 (es) Matriz polimerica insoluble en agua para la administracion de farmacos
CY1110133T1 (el) Θεραπευτικος παραγων υπερλιπαιμιας που περιλαμβανει πιταβαστατινες και εικοσαπενταενοϊκο οξυ
UY28067A1 (es) Formulaciones de deposito de liberacion controlada
ES2570856T3 (es) Composiciones oftálmicas que contienen una combinación sinérgica de dos polímeros
PE20080389A1 (es) Composicion supresora de polvo
BRPI0513921A (pt) composição para cuidado oral, e, método para liberar um ativo para cuidado oral
ATE464002T1 (de) Verlängerungen für chirurgischen retraktor
CO5640073A2 (es) Peliculas consumibles oralmente de disolucion rapida que contienen un almidon modificado para la mejora de la resistencia al calor y a la humedad
AR070614A1 (es) Microesferas polimericas como aditivos biodegradables contra perdida de fluido en aplicaciones de campo petrolero
ES2133907T3 (es) Composicion estable que contiene un agente activo cosmetico y/o dermatologico sensible al agua.
CY1108700T1 (el) Συνθεσεις απελευθερωσης φαρμακου εστερα αλφα-υδροξυ οξεος και μεθοδοι χρησης
NO20032850L (no) Gjennomhullet polymerfilmbane med diol/surfaktantadditiv
ATE406194T1 (de) Verwendung von gefüllten amphiphilen statistischen polymeren zum eindicken von riesenmizellen enthaltenden phasen und wässrige zusammensetzung davon
UY31699A1 (es) Suspensiones de acetonido de triamcinolona de baja viscosidad y elevada floculacion para inyeccion intravitrea
FR2871057B1 (fr) Composition cosmetique contenant un ester et un agent filmogene
PE20180575A1 (es) Benzamidas sustituidas y metodos para utilizarlas
AR094290A1 (es) Composiciones y metodos para la administracion transdermica de agentes antiinflamatorios no esteroideos
CL2008001072A1 (es) Bloque de limpieza de inodoro que es al menos parcialmente transparente o translucida, que comprende 2 - 50% de material biocida y 50 - 98% de composicion portadora que comprende 5 - 50% de agente jabon, 30 - 90% de humectante, 5 - 30% de solvente; metodo para proporcionar higiene en un inodoro; y uso del bloque
CY1108069T1 (el) Φαρμακευτικη συνθεση σε μορφη υδρογελης για διαδερμικη χορηγηση δραστικων ουσιων
AR063748A1 (es) Formulacion
ES2530874T3 (es) Formulaciones de depósito de corta duración
AR061655A1 (es) Composicion de microesferas polimericas degradables
AR030941A1 (es) Composicion liberable y metodo de preparacion

Legal Events

Date Code Title Description
FC Refusal