AR065176A1 - Poliformos de acido [ 1 - ( 4 - terc - butil -bencil ) - 5 - ( 3 - metilfenil ) - 1 h - indol - 3 - i l ) ( oxo ) acetico ; composiciones farmaceuticas y mezclas que lo comprenden; metodos para preparar los polimoformos, tratar trombosis o deterioro fibrinolitico, isquemia miocardica, enfermedad de - Google Patents

Poliformos de acido [ 1 - ( 4 - terc - butil -bencil ) - 5 - ( 3 - metilfenil ) - 1 h - indol - 3 - i l ) ( oxo ) acetico ; composiciones farmaceuticas y mezclas que lo comprenden; metodos para preparar los polimoformos, tratar trombosis o deterioro fibrinolitico, isquemia miocardica, enfermedad de

Info

Publication number
AR065176A1
AR065176A1 ARP080100473A ARP080100473A AR065176A1 AR 065176 A1 AR065176 A1 AR 065176A1 AR P080100473 A ARP080100473 A AR P080100473A AR P080100473 A ARP080100473 A AR P080100473A AR 065176 A1 AR065176 A1 AR 065176A1
Authority
AR
Argentina
Prior art keywords
oxo
polymophorms
polyforms
methylpenyl
bencil
Prior art date
Application number
ARP080100473A
Other languages
English (en)
Inventor
Hsueh-Ling Wu
Abdolsamad Tadayon
Mannching Sherry Ku
David Zenan Li
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of AR065176A1 publication Critical patent/AR065176A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/22—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an aralkyl radical attached to the ring nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Vascular Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Reivindicacion 1: Un polimorfo (Forma A) de ácido [1-(4-terc-Butilbencil)-5-(3-metilfenil)-1H-indol-3- il](oxo)acético, caracterizado porque tiene un patron de difraccion de rayos X en polvo que comprende picos característicos, en términos de 2theta, en 6.5° y 10.9°.
ARP080100473A 2007-02-05 2008-02-05 Poliformos de acido [ 1 - ( 4 - terc - butil -bencil ) - 5 - ( 3 - metilfenil ) - 1 h - indol - 3 - i l ) ( oxo ) acetico ; composiciones farmaceuticas y mezclas que lo comprenden; metodos para preparar los polimoformos, tratar trombosis o deterioro fibrinolitico, isquemia miocardica, enfermedad de AR065176A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US89947307P 2007-02-05 2007-02-05

Publications (1)

Publication Number Publication Date
AR065176A1 true AR065176A1 (es) 2009-05-20

Family

ID=39676711

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP080100473A AR065176A1 (es) 2007-02-05 2008-02-05 Poliformos de acido [ 1 - ( 4 - terc - butil -bencil ) - 5 - ( 3 - metilfenil ) - 1 h - indol - 3 - i l ) ( oxo ) acetico ; composiciones farmaceuticas y mezclas que lo comprenden; metodos para preparar los polimoformos, tratar trombosis o deterioro fibrinolitico, isquemia miocardica, enfermedad de

Country Status (8)

Country Link
US (1) US20080188542A1 (es)
EP (1) EP2061757A2 (es)
AR (1) AR065176A1 (es)
CL (1) CL2008000354A1 (es)
PA (1) PA8768801A1 (es)
PE (1) PE20081757A1 (es)
TW (1) TW200840564A (es)
WO (1) WO2008097938A2 (es)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7074817B2 (en) * 2001-06-20 2006-07-11 Wyeth Substituted indole acid derivatives as inhibitors of plasminogen activator inhibitor-1 (PAI-1)

Also Published As

Publication number Publication date
EP2061757A2 (en) 2009-05-27
US20080188542A1 (en) 2008-08-07
PE20081757A1 (es) 2009-01-21
TW200840564A (en) 2008-10-16
WO2008097938A3 (en) 2009-09-11
WO2008097938A2 (en) 2008-08-14
CL2008000354A1 (es) 2008-03-14
PA8768801A1 (es) 2009-02-09

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