AR063109A1 - Terapias topicas para la mucositis oral y otras afecciones - Google Patents
Terapias topicas para la mucositis oral y otras afeccionesInfo
- Publication number
- AR063109A1 AR063109A1 ARP070104372A ARP070104372A AR063109A1 AR 063109 A1 AR063109 A1 AR 063109A1 AR P070104372 A ARP070104372 A AR P070104372A AR P070104372 A ARP070104372 A AR P070104372A AR 063109 A1 AR063109 A1 AR 063109A1
- Authority
- AR
- Argentina
- Prior art keywords
- phenytoin
- oral mucositis
- salt
- oral
- mucosa
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Emergency Medicine (AREA)
- Neurosurgery (AREA)
- Rheumatology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
Método para tratar la mucositis oral que comprende administrar de forma topica sobre una superficie de la mucosa oral del sujeto fenitoína, o una sal aceptable para uso farmacéutico de la misma, en una cantidad eficaz para inhibir la degeneracion de la mucosa o promover la regeneracion de la mucosa, y, opcionalmente, una cantidad eficaz de un agente analgésico como por ejemplo morfina, entre otros, en combinacion con la fenitoína o una sal de la misma, para reducir el dolor asociado con la mucositis oral. La fenitoína, o una sal de la misma, y opcionalmente el agente analgésico se pueden administrar en una composicion farmacéutica que comprende un vehículo excipiente adecuado para una administracion intraoral, donde dicha composicion es bioadhesiva a una superficie de la mucosa oral, que contiene por ejemplo al menos una fase interna no lipoide y al menos una fase externa lipoide que es bioadhesiva a dicha superficie.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US82831906P | 2006-10-05 | 2006-10-05 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR063109A1 true AR063109A1 (es) | 2008-12-30 |
Family
ID=39322783
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP070104372A AR063109A1 (es) | 2006-10-05 | 2007-10-02 | Terapias topicas para la mucositis oral y otras afecciones |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20080299050A1 (es) |
| AR (1) | AR063109A1 (es) |
| CL (1) | CL2007002837A1 (es) |
| PE (1) | PE20081114A1 (es) |
| WO (1) | WO2008060764A2 (es) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6057287A (en) | 1994-01-11 | 2000-05-02 | Dyax Corp. | Kallikrein-binding "Kunitz domain" proteins and analogues thereof |
| EP2298278B1 (en) | 2002-06-07 | 2015-11-11 | Dyax Corp. | Prevention and reduction of blood loss and inflammatory response |
| US7153829B2 (en) | 2002-06-07 | 2006-12-26 | Dyax Corp. | Kallikrein-inhibitor therapies |
| SI2386310T1 (sl) | 2002-08-28 | 2019-03-29 | Dyax Corp. | Metode za ohranjanje organov in tkiv |
| US7235530B2 (en) | 2004-09-27 | 2007-06-26 | Dyax Corporation | Kallikrein inhibitors and anti-thrombolytic agents and uses thereof |
| AU2010203712A1 (en) | 2009-01-06 | 2010-07-15 | Dyax Corp. | Treatment of mucositis with kallikrein inhibitors |
| CA2763092A1 (en) | 2009-06-10 | 2010-12-16 | Exthera Ab | Use of a composition for the treatment of mucositis |
| US8829020B2 (en) | 2009-07-16 | 2014-09-09 | Mallinckrodt Llc | Compounds and compositions for use in phototherapy and in treatment of ocular neovascular disease and cancers |
| LT2521568T (lt) | 2010-01-06 | 2018-12-10 | Dyax Corp. | Plazmos kalikreiną surišantys baltymai |
| BR112013017080A8 (pt) | 2011-01-06 | 2023-05-09 | Dyax Corp | Anticorpo ou fragmento funcional do mesmo que se liga a forma ativa de calicreína do plasma humano, composiçao farmacêutica e método de detecçao de calicreína do plasma em um paciente |
| PL2701681T3 (pl) | 2011-04-29 | 2017-03-31 | Moberg Pharma Ab | Kompozycje farmaceutyczne zawierające środek miejscowo znieczulający, taki jak bupiwakaina, do podawania miejscowego do jamy ustnej lub gardła |
| EP2874824A1 (en) | 2012-07-23 | 2015-05-27 | Crayola LLC | Dissolvable films and methods of using the same |
| AU2014243929B2 (en) * | 2013-03-14 | 2019-01-17 | 3 In 1 Dental Pllc | Compositions for treatment of xerostomia and for tooth treatment |
| WO2015013549A1 (en) * | 2013-07-25 | 2015-01-29 | Invado Pharmaceuticals, LLC | Treating oral inflammation, injury or pain |
| WO2015101693A1 (es) * | 2013-12-31 | 2015-07-09 | Servicio Andaluz De Salud | Composiciones y preparaciones combinadas para el tratamiento de las algias orofaríngeas |
| US11103546B2 (en) | 2014-01-29 | 2021-08-31 | Vita Ice Therapeutics Llc | Edible oil compositions to treat oral complications and methods of using same |
| US9763934B2 (en) * | 2014-03-05 | 2017-09-19 | Professional Compounding Centers Of America | Synergistic effect of poloxamer-based composition and itraconazole on fungus and yeast |
| US10428158B2 (en) | 2014-03-27 | 2019-10-01 | Dyax Corp. | Compositions and methods for treatment of diabetic macular edema |
| BR112018011622A2 (pt) | 2015-12-11 | 2018-11-27 | Dyax Corp | método para tratar ataque de angioedema hereditário (hae) ou reduzir a taxa de ataque de hae |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5589480A (en) * | 1994-08-17 | 1996-12-31 | Elkhoury; George F. | Topical application of opioid analgesic drugs such as morphine |
| US6274168B1 (en) * | 1999-02-23 | 2001-08-14 | Mylan Pharmaceuticals Inc. | Phenytoin sodium pharmaceutical compositions |
| US20020013331A1 (en) * | 2000-06-26 | 2002-01-31 | Williams Robert O. | Methods and compositions for treating pain of the mucous membrane |
| US6906038B2 (en) * | 2001-08-29 | 2005-06-14 | Abbott Laboratories | Methods for alleviating mucositis |
| WO2004005338A1 (en) * | 2002-07-08 | 2004-01-15 | Genova, Ltd. | Secreted peptides |
-
2007
- 2007-10-01 WO PCT/US2007/080051 patent/WO2008060764A2/en active Application Filing
- 2007-10-01 US US11/865,476 patent/US20080299050A1/en not_active Abandoned
- 2007-10-02 CL CL200702837A patent/CL2007002837A1/es unknown
- 2007-10-02 AR ARP070104372A patent/AR063109A1/es unknown
- 2007-10-02 PE PE2007001327A patent/PE20081114A1/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CL2007002837A1 (es) | 2008-07-18 |
| WO2008060764A2 (en) | 2008-05-22 |
| WO2008060764A3 (en) | 2008-07-24 |
| PE20081114A1 (es) | 2008-08-28 |
| US20080299050A1 (en) | 2008-12-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |