AR047436A1 - Compuesto de piperidin-2-ona1,6-disubstituido, solucion oftalmica que lo comprende, producto farmaceutico que comprende esta ultima y uso del compuesto para preparar dicha solucion oftalmica - Google Patents
Compuesto de piperidin-2-ona1,6-disubstituido, solucion oftalmica que lo comprende, producto farmaceutico que comprende esta ultima y uso del compuesto para preparar dicha solucion oftalmicaInfo
- Publication number
- AR047436A1 AR047436A1 ARP050100195A ARP050100195A AR047436A1 AR 047436 A1 AR047436 A1 AR 047436A1 AR P050100195 A ARP050100195 A AR P050100195A AR P050100195 A ARP050100195 A AR P050100195A AR 047436 A1 AR047436 A1 AR 047436A1
- Authority
- AR
- Argentina
- Prior art keywords
- ophthalmic solution
- compound
- container
- general formula
- configuration
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 4
- 229940054534 ophthalmic solution Drugs 0.000 title abstract 4
- 239000002997 ophthalmic solution Substances 0.000 title abstract 4
- 239000000825 pharmaceutical preparation Substances 0.000 title abstract 2
- 229940127557 pharmaceutical product Drugs 0.000 title abstract 2
- 239000002131 composite material Substances 0.000 title 1
- 208000010412 Glaucoma Diseases 0.000 abstract 2
- 206010030043 Ocular hypertension Diseases 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- -1 1,6-disubstituted piperidin-2-one compound Chemical class 0.000 abstract 1
- 101150047265 COR2 gene Proteins 0.000 abstract 1
- 125000000520 N-substituted aminocarbonyl group Chemical group [*]NC(=O)* 0.000 abstract 1
- 101100467189 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) QCR2 gene Proteins 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000000499 benzofuranyl group Chemical group O1C(=CC2=C1C=CC=C2)* 0.000 abstract 1
- 125000004196 benzothienyl group Chemical group S1C(=CC2=C1C=CC=C2)* 0.000 abstract 1
- 125000002541 furyl group Chemical group 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 125000001624 naphthyl group Chemical group 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 125000004076 pyridyl group Chemical group 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
- 125000001544 thienyl group Chemical group 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/06—Peri-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/45—Non condensed piperidines, e.g. piperocaine having oxo groups directly attached to the heterocyclic ring, e.g. cycloheximide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D211/74—Oxygen atoms
- C07D211/76—Oxygen atoms attached in position 2 or 6
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Ophthalmology & Optometry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/763,702 US6977260B2 (en) | 2004-01-22 | 2004-01-22 | Piperidinyl prostaglandin E analogs |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR047436A1 true AR047436A1 (es) | 2006-01-18 |
Family
ID=34795110
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP050100195A AR047436A1 (es) | 2004-01-22 | 2005-01-20 | Compuesto de piperidin-2-ona1,6-disubstituido, solucion oftalmica que lo comprende, producto farmaceutico que comprende esta ultima y uso del compuesto para preparar dicha solucion oftalmica |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US6977260B2 (enExample) |
| EP (1) | EP1722795B1 (enExample) |
| JP (1) | JP4740883B2 (enExample) |
| AR (1) | AR047436A1 (enExample) |
| AT (1) | ATE394101T1 (enExample) |
| AU (1) | AU2005209209B2 (enExample) |
| CA (1) | CA2553387C (enExample) |
| DE (1) | DE602005006534D1 (enExample) |
| ES (1) | ES2303672T3 (enExample) |
| TW (1) | TWI348370B (enExample) |
| WO (1) | WO2005072735A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7326716B2 (en) * | 2003-06-06 | 2008-02-05 | Allergan, Inc. | Treatment of inflammatory bowel disease |
| US20060135609A1 (en) * | 2004-10-21 | 2006-06-22 | Duke University | Ophthamological drugs |
| US20070254920A1 (en) * | 2006-04-26 | 2007-11-01 | Aerie Pharmaceuticals, Inc. | Prodrug derivatives of acids using alcohols with homotopic hydroxy groups and methods for their preparation and use |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3220156C2 (de) * | 1982-05-28 | 1990-01-25 | Heida Houston Tex. Thurlow | Mit Metallgriffen, insbesondere Edelstahlgriffen, versehenes Koch- und Bratgeschirr mit Deckel |
| IT1225716B (it) * | 1988-10-26 | 1990-11-22 | Esacontrol Spa | Dispositivo per la protezione dei rele' di binario dai disturbi elettrici |
| CA2021316C (en) | 1989-07-27 | 2000-10-24 | Ming Fai Chan | Intraocular pressure reducing 11-acyl prostaglandins |
| US4994274A (en) * | 1989-07-27 | 1991-02-19 | Allergan, Inc. | Intraocular pressure reducing 11,15-diacyl prostaglandins and method of using |
| US5034413A (en) | 1989-07-27 | 1991-07-23 | Allergan, Inc. | Intraocular pressure reducing 9,11-diacyl prostaglandins |
| US5028624A (en) * | 1989-07-27 | 1991-07-02 | Allergan, Inc. | Intraocular pressure reducing 9,15-diacyl prostaglandins |
| DE4318713C1 (de) * | 1993-06-07 | 1994-09-15 | Daimler Benz Ag | Zahnräderwechselgetriebe der Vorgelegebauart |
| EP1513589B1 (en) * | 2002-06-06 | 2010-11-10 | Merck Frosst Canada Ltd. | 1,5-disubstituted pyrrolid-2-one derivatives for use as ep4 receptor agonists in the treatment of eye diseases such as glaucoma |
| US7053085B2 (en) | 2003-03-26 | 2006-05-30 | Merck & Co. Inc. | EP4 receptor agonist, compositions and methods thereof |
| JP2006515015A (ja) | 2003-01-10 | 2006-05-18 | エフ．ホフマン−ラ ロシュ アーゲー | プロスタグランジンアゴニストとしての２−ピペリドン誘導体 |
| US6747037B1 (en) * | 2003-06-06 | 2004-06-08 | Allergan, Inc. | Piperidinyl prostaglandin E analogs |
| CA2528179C (en) * | 2003-06-06 | 2013-10-22 | Allergan, Inc. | Piperidinyl prostaglandin e analogs |
-
2004
- 2004-01-22 US US10/763,702 patent/US6977260B2/en not_active Expired - Lifetime
-
2005
- 2005-01-07 TW TW094100542A patent/TWI348370B/zh not_active IP Right Cessation
- 2005-01-14 CA CA2553387A patent/CA2553387C/en not_active Expired - Fee Related
- 2005-01-14 ES ES05705822T patent/ES2303672T3/es not_active Expired - Lifetime
- 2005-01-14 AU AU2005209209A patent/AU2005209209B2/en not_active Ceased
- 2005-01-14 AT AT05705822T patent/ATE394101T1/de not_active IP Right Cessation
- 2005-01-14 WO PCT/US2005/001461 patent/WO2005072735A1/en not_active Ceased
- 2005-01-14 JP JP2006551189A patent/JP4740883B2/ja not_active Expired - Fee Related
- 2005-01-14 DE DE602005006534T patent/DE602005006534D1/de not_active Expired - Lifetime
- 2005-01-14 EP EP05705822A patent/EP1722795B1/en not_active Expired - Lifetime
- 2005-01-20 AR ARP050100195A patent/AR047436A1/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EP1722795A1 (en) | 2006-11-22 |
| ES2303672T3 (es) | 2008-08-16 |
| AU2005209209A1 (en) | 2005-08-11 |
| CA2553387C (en) | 2013-04-02 |
| HK1099203A1 (en) | 2007-08-10 |
| TW200533350A (en) | 2005-10-16 |
| JP4740883B2 (ja) | 2011-08-03 |
| EP1722795B1 (en) | 2008-05-07 |
| US6977260B2 (en) | 2005-12-20 |
| AU2005209209B2 (en) | 2012-03-08 |
| JP2007520489A (ja) | 2007-07-26 |
| CA2553387A1 (en) | 2005-08-11 |
| US20050164990A1 (en) | 2005-07-28 |
| TWI348370B (en) | 2011-09-11 |
| DE602005006534D1 (de) | 2008-06-19 |
| ATE394101T1 (de) | 2008-05-15 |
| WO2005072735A1 (en) | 2005-08-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |