AR041536A1 - Derivados metaestables de benzoxepina que pueden ser usados en el tratamiento de dislipidemia, ateroesclerosis y diabetes, composiciones farmaceuticas que los contienen y procedimientos para su preparacion - Google Patents

Derivados metaestables de benzoxepina que pueden ser usados en el tratamiento de dislipidemia, ateroesclerosis y diabetes, composiciones farmaceuticas que los contienen y procedimientos para su preparacion

Info

Publication number
AR041536A1
AR041536A1 ARP030103639A ARP030103639A AR041536A1 AR 041536 A1 AR041536 A1 AR 041536A1 AR P030103639 A ARP030103639 A AR P030103639A AR P030103639 A ARP030103639 A AR P030103639A AR 041536 A1 AR041536 A1 AR 041536A1
Authority
AR
Argentina
Prior art keywords
metastable
aterosclerosis
benzoxepin
dyslipidemia
diabetes
Prior art date
Application number
ARP030103639A
Other languages
English (en)
Inventor
Nathalie Bosc
Bernard Boudet
Festal Didier Dr
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of AR041536A1 publication Critical patent/AR041536A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
    • C07D313/02—Seven-membered rings
    • C07D313/06—Seven-membered rings condensed with carbocyclic rings or ring systems
    • C07D313/08—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrane Compounds (AREA)

Abstract

Reivindicación 1: Forma metaestable de los compuestos de fórmula 1, en la cual: n representa 0, 1 ó 2; y los radicales R, los cuales pueden ser idénticos o diferentes, son grupos alquilo o alcoxi, o átomos de halógeno.
ARP030103639A 2002-10-07 2003-10-07 Derivados metaestables de benzoxepina que pueden ser usados en el tratamiento de dislipidemia, ateroesclerosis y diabetes, composiciones farmaceuticas que los contienen y procedimientos para su preparacion AR041536A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0212432A FR2845386B1 (fr) 2002-10-07 2002-10-07 Nouveaux derives metastables de benzoxepines utilisables dans le traitement des dyslipidemies, de l'atherosclerose et du diabete, compositions pharmaceutiques les contenant et procedes de preparation

Publications (1)

Publication Number Publication Date
AR041536A1 true AR041536A1 (es) 2005-05-18

Family

ID=32011471

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP030103639A AR041536A1 (es) 2002-10-07 2003-10-07 Derivados metaestables de benzoxepina que pueden ser usados en el tratamiento de dislipidemia, ateroesclerosis y diabetes, composiciones farmaceuticas que los contienen y procedimientos para su preparacion

Country Status (8)

Country Link
US (1) US7470719B2 (es)
EP (1) EP1549630A1 (es)
JP (1) JP4856376B2 (es)
AR (1) AR041536A1 (es)
AU (1) AU2003264139B2 (es)
CA (1) CA2502877C (es)
FR (1) FR2845386B1 (es)
WO (1) WO2004031166A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2845386B1 (fr) 2002-10-07 2006-06-30 Merck Sante Sas Nouveaux derives metastables de benzoxepines utilisables dans le traitement des dyslipidemies, de l'atherosclerose et du diabete, compositions pharmaceutiques les contenant et procedes de preparation
CA2544147A1 (en) 2005-04-20 2006-10-20 Espeed, Inc. Systems and methods for maintaining the viability of a good-until-bettered order type in electronic trading systems
JP5764060B2 (ja) * 2008-08-12 2015-08-12 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングＭｅｒｃｋ Ｐａｔｅｎｔ Ｇｅｓｅｌｌｓｃｈａｆｔ ｍｉｔ ｂｅｓｃｈｒａｅｎｋｔｅｒ Ｈａｆｔｕｎｇ 化粧品としての５−（７−メトキシ−３，３−ジメチル−２，３−ジヒドロ−１−ベンゾオキセピン−５−イル）−３−メチル−ペンタ−２，４−ジエン酸の使用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2787789B1 (fr) * 1998-12-29 2002-06-14 Lipha Benzopyranes et benzoxepines utilisables dans le traitement de dyslipidemies, de l'atherosclerose et du diabete, compositions pharmaceutiques les contenant et procedes de preparations
FR2845386B1 (fr) 2002-10-07 2006-06-30 Merck Sante Sas Nouveaux derives metastables de benzoxepines utilisables dans le traitement des dyslipidemies, de l'atherosclerose et du diabete, compositions pharmaceutiques les contenant et procedes de preparation

Also Published As

Publication number Publication date
CA2502877C (en) 2011-07-26
FR2845386B1 (fr) 2006-06-30
JP2006503073A (ja) 2006-01-26
CA2502877A1 (en) 2004-04-15
US20060041007A1 (en) 2006-02-23
AU2003264139A1 (en) 2004-04-23
AU2003264139B2 (en) 2009-09-03
US7470719B2 (en) 2008-12-30
FR2845386A1 (fr) 2004-04-09
EP1549630A1 (en) 2005-07-06
JP4856376B2 (ja) 2012-01-18
WO2004031166A1 (en) 2004-04-15

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Legal Events

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FA Abandonment or withdrawal