AR032876A1 - CARBAMATE COMPOUNDS FOR USE IN THE PREVENTION OR TREATMENT OF PSYCHOTIC DISORDERS - Google Patents

CARBAMATE COMPOUNDS FOR USE IN THE PREVENTION OR TREATMENT OF PSYCHOTIC DISORDERS

Info

Publication number
AR032876A1
AR032876A1 ARP020100702A ARP020100702A AR032876A1 AR 032876 A1 AR032876 A1 AR 032876A1 AR P020100702 A ARP020100702 A AR P020100702A AR P020100702 A ARP020100702 A AR P020100702A AR 032876 A1 AR032876 A1 AR 032876A1
Authority
AR
Argentina
Prior art keywords
group
psychotic disorders
phenyl
alkyl
prevention
Prior art date
Application number
ARP020100702A
Other languages
Spanish (es)
Original Assignee
Ortho Mcneil Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho Mcneil Pharm Inc filed Critical Ortho Mcneil Pharm Inc
Publication of AR032876A1 publication Critical patent/AR032876A1/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/325Carbamic acids; Thiocarbamic acids; Anhydrides or salts thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants

Abstract

La presente hace referencia a un método para prevenir o tratar trastornos psicoticos que comprende la administracion a un paciente que lo necesita de una cantidad terapéuticamente eficaz de un compuesto seleccionado del grupo formado por las formulas (1) y (2). Donde fenilo se sustituye en X con uno a cinco átomos de halogeno seleccionados del grupo compuesto por fluor, bromo, y yodo; R1, R2, R3, R4, R5 y R6 son independientemente seleccionados del grupo compuesto por hidrogeno y alquilo de C1-4; donde el alquilo de C1-4 es opcionalmente sustituido con fenilo (en el cual el fenilo es opcionalmente sustituido con sustituyentes independientemente seleccionado del grupo compuesto por halogeno, alquilo de C1-4, alcoxi de C1-4, amino, nitro y ciano).This refers to a method to prevent or treat psychotic disorders that comprises administering to a patient in need of a therapeutically effective amount of a compound selected from the group consisting of formulas (1) and (2). Where phenyl is substituted at X with one to five halogen atoms selected from the group consisting of fluorine, bromine, and iodine; R1, R2, R3, R4, R5 and R6 are independently selected from the group consisting of hydrogen and C1-4 alkyl; wherein the C1-4 alkyl is optionally substituted with phenyl (in which the phenyl is optionally substituted with substituents independently selected from the group consisting of halogen, C1-4 alkyl, C1-4 alkoxy, amino, nitro and cyano).

ARP020100702A 2001-02-27 2002-02-27 CARBAMATE COMPOUNDS FOR USE IN THE PREVENTION OR TREATMENT OF PSYCHOTIC DISORDERS AR032876A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US27188901P 2001-02-27 2001-02-27
US10/081,761 US6541513B2 (en) 2001-02-27 2002-02-21 Carbamate compounds for use in preventing or treating psychotic disorders

Publications (1)

Publication Number Publication Date
AR032876A1 true AR032876A1 (en) 2003-11-26

Family

ID=26765939

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP020100702A AR032876A1 (en) 2001-02-27 2002-02-27 CARBAMATE COMPOUNDS FOR USE IN THE PREVENTION OR TREATMENT OF PSYCHOTIC DISORDERS

Country Status (25)

Country Link
US (1) US6541513B2 (en)
EP (1) EP1401424B1 (en)
JP (1) JP4276841B2 (en)
KR (1) KR100886578B1 (en)
CN (1) CN1262271C (en)
AR (1) AR032876A1 (en)
AT (1) ATE346597T1 (en)
AU (1) AU2002242296B2 (en)
BR (1) BR0207829A (en)
CA (1) CA2439480C (en)
CZ (1) CZ302412B6 (en)
DE (1) DE60216457T2 (en)
DK (1) DK1401424T3 (en)
ES (1) ES2275844T3 (en)
HU (1) HUP0303342A3 (en)
IL (2) IL157588A0 (en)
MX (1) MXPA03007722A (en)
NO (1) NO20033801L (en)
NZ (1) NZ527991A (en)
PL (1) PL365021A1 (en)
PT (1) PT1401424E (en)
RS (1) RS51056B (en)
RU (1) RU2302240C2 (en)
TW (1) TWI251486B (en)
WO (1) WO2002067927A1 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1305082E (en) * 2000-07-21 2004-09-30 Ortho Mcneil Pharm Inc CARBAMATE COMPOUNDS FOR USE IN THE PREVENTION OR TREATMENT OF NEUROPATHIC PAIN AND PAIN ASSOCIATED WITH SAFEGUARD OF SALVAS AND ENXAQUECA
EP1399144B1 (en) 2001-02-27 2006-04-26 Ortho-Mcneil Pharmaceutical, Inc. Carbamate compounds for use in preventing or treating anxiety disorders
DE60220043T2 (en) * 2001-02-27 2008-01-10 Ortho-Mcneil Pharmaceutical, Inc. CARBAMATE COMPOUNDS FOR PREVENTING OR TREATING NEURODEEGENERATIVE DISORDER
RS50948B (en) 2001-07-16 2010-08-31 Ortho-Mcneil Pharmaceutical Inc. Carbamate compounds for use in preventing or treating neuropathic pain
WO2005107719A2 (en) * 2004-05-06 2005-11-17 Sandoz Ag Pharmaceutical composition comprising hydrophobic drug having improved solubility
EP1928451B1 (en) * 2005-07-26 2011-12-28 SK Biopharmaceuticals Co., LTD Methods for treating substance-related disorders
EP2081648A2 (en) * 2006-10-30 2009-07-29 Janssen Pharmaceutica, N.V. Carbamate compounds for use in treating depression
EP2089011A1 (en) * 2006-10-31 2009-08-19 Janssen Pharmaceutica N.V. Treatment of pervasive developmental disorders
US8609849B1 (en) 2010-11-30 2013-12-17 Fox Chase Chemical Diversity Center, Inc. Hydroxylated sulfamides exhibiting neuroprotective action and their method of use
CN109939092B (en) 2013-03-12 2022-03-22 比皮艾思药物研发有限公司 Phenyl carbamate compounds for use in preventing or treating pediatric epilepsy and epilepsy-related syndrome
KR102014615B1 (en) * 2013-03-12 2019-08-27 (주)바이오팜솔루션즈 Phenyl carbamate compound and a composition for neuroprotection comprising the same

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3313692A (en) * 1958-04-21 1967-04-11 Armour Pharma Method of inducing calming and muscle relaxation with carbamates
US3265728A (en) * 1962-07-18 1966-08-09 Armour Pharma Substituted phenethyl carbamates
US5492930A (en) * 1994-04-25 1996-02-20 Schering Corporation Method and formulation for treating CNS disorders
US5698588A (en) * 1996-01-16 1997-12-16 Yukong Limited Halogen substituted carbamate compounds from 2-phenyl-1,2-ethanediol

Also Published As

Publication number Publication date
DE60216457T2 (en) 2007-09-20
PL365021A1 (en) 2004-12-27
RS51056B (en) 2010-10-31
CN1262271C (en) 2006-07-05
BR0207829A (en) 2004-06-22
HUP0303342A3 (en) 2012-07-30
RS67503A (en) 2006-12-15
NO20033801D0 (en) 2003-08-26
RU2302240C2 (en) 2007-07-10
NZ527991A (en) 2005-04-29
DE60216457D1 (en) 2007-01-11
CN1505507A (en) 2004-06-16
CA2439480C (en) 2011-04-26
IL157588A0 (en) 2004-03-28
HUP0303342A2 (en) 2004-01-28
DK1401424T3 (en) 2007-02-26
TWI251486B (en) 2006-03-21
US20020165272A1 (en) 2002-11-07
WO2002067927A1 (en) 2002-09-06
IL157588A (en) 2009-12-24
EP1401424B1 (en) 2006-11-29
CA2439480A1 (en) 2002-09-06
ES2275844T3 (en) 2007-06-16
CZ302412B6 (en) 2011-05-04
KR20030076713A (en) 2003-09-26
CZ20032297A3 (en) 2004-06-16
ATE346597T1 (en) 2006-12-15
PT1401424E (en) 2007-02-28
NO20033801L (en) 2003-10-22
RU2003128983A (en) 2005-03-10
US6541513B2 (en) 2003-04-01
MXPA03007722A (en) 2004-11-12
KR100886578B1 (en) 2009-03-05
EP1401424A1 (en) 2004-03-31
AU2002242296B2 (en) 2006-06-29
JP2004523556A (en) 2004-08-05
JP4276841B2 (en) 2009-06-10

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