CR9766A - METHODS FOR THE TREATMENT OF SUBSTANCE-RELATED DISORDERS - Google Patents

METHODS FOR THE TREATMENT OF SUBSTANCE-RELATED DISORDERS

Info

Publication number
CR9766A
CR9766A CR9766A CR9766A CR9766A CR 9766 A CR9766 A CR 9766A CR 9766 A CR9766 A CR 9766A CR 9766 A CR9766 A CR 9766A CR 9766 A CR9766 A CR 9766A
Authority
CR
Costa Rica
Prior art keywords
substance
phenyl
alkyl
group
treatment
Prior art date
Application number
CR9766A
Other languages
Spanish (es)
Inventor
R Plata-Salaman Carlos
Zhao Boyu
E Twymman Roy
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Priority to CR9766A priority Critical patent/CR9766A/en
Publication of CR9766A publication Critical patent/CR9766A/en

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  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Esta invencion esta dirigida a un metodo para prevenir, tratar o aliviar trastornos relacionados con sustancias, en un sujeto que necesita el mismo que comprende administrar al sujeto una cantidad efectiva de un compuesto seleccionado de la formula (I) o la formula (II): o formas farmaceuticamente aceptables del mismo, en donde el fenilo es sustituido en X con uno a cinco atomos de halogeno seleccionados del grupo que consiste de fluor, cloro, bromo y yodo, y R1, R2, R3, R4, R5, y R6 se seleccionan independientemente del grupo que consiste de hidrogeno y alquilo de C1-4 en donde alquilo de c1-4 es opcionalmente sustituido con fenilo (y, en donde el fenilo es opcionalmente sustituido con sustituyentes independientemente seleccionados del grupo que consiste de halogeno, alquilo de c1-4, alcoxi de C1-C4, amino, nitro y ciano); ademas, se incluyen metodos que implican la co-administracion de compuestos de la invencion con uno o mas compuestos conocidos para el tratamiento de trastornos inducidos por sustancias.This invention is directed to a method for preventing, treating or alleviating substance-related disorders, in a subject that needs the same which comprises administering to the subject an effective amount of a compound selected from the formula (I) or the formula (II): or pharmaceutically acceptable forms thereof, wherein the phenyl is substituted in X with one to five halogen atoms selected from the group consisting of fluorine, chlorine, bromine and iodine, and R1, R2, R3, R4, R5, and R6 are independently selected from the group consisting of hydrogen and C1-4 alkyl wherein C1-4 alkyl is optionally substituted with phenyl (and, wherein the phenyl is optionally substituted with substituents independently selected from the group consisting of halogen, C1 alkyl -4, C1-C4 alkoxy, amino, nitro and cyano); In addition, methods involving the co-administration of compounds of the invention with one or more known compounds for the treatment of substance-induced disorders are included.

CR9766A 2008-02-26 2008-02-26 METHODS FOR THE TREATMENT OF SUBSTANCE-RELATED DISORDERS CR9766A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CR9766A CR9766A (en) 2008-02-26 2008-02-26 METHODS FOR THE TREATMENT OF SUBSTANCE-RELATED DISORDERS

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CR9766A CR9766A (en) 2008-02-26 2008-02-26 METHODS FOR THE TREATMENT OF SUBSTANCE-RELATED DISORDERS

Publications (1)

Publication Number Publication Date
CR9766A true CR9766A (en) 2008-09-09

Family

ID=44839415

Family Applications (1)

Application Number Title Priority Date Filing Date
CR9766A CR9766A (en) 2008-02-26 2008-02-26 METHODS FOR THE TREATMENT OF SUBSTANCE-RELATED DISORDERS

Country Status (1)

Country Link
CR (1) CR9766A (en)
  • 2008

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Legal Events

Date Code Title Description
FA Abandonment or withdrawal (granting procedure)