AR028957A1 - SEPARATION BETWEEN DWELLERS OF PIPERIDONE DERIVATIVES WITH SIMULATE NEA RACEMIZATION IN SITU OF INDENATED ENANTIUM - Google Patents

SEPARATION BETWEEN DWELLERS OF PIPERIDONE DERIVATIVES WITH SIMULATE NEA RACEMIZATION IN SITU OF INDENATED ENANTIUM

Info

Publication number
AR028957A1
AR028957A1 ARP010102869A ARP010102869A AR028957A1 AR 028957 A1 AR028957 A1 AR 028957A1 AR P010102869 A ARP010102869 A AR P010102869A AR P010102869 A ARP010102869 A AR P010102869A AR 028957 A1 AR028957 A1 AR 028957A1
Authority
AR
Argentina
Prior art keywords
racemization
situ
separation
indenated
enantium
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Suspension/Interruption
Application number
ARP010102869A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH Co KG
Original Assignee
Boehringer Ingelheim Pharma GmbH Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Pharma GmbH Co KG filed Critical Boehringer Ingelheim Pharma GmbH Co KG
Publication of AR028957A1 publication Critical patent/AR028957A1/en
Suspension/Interruption legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D211/74—Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

El invento se refiere a un procedimiento aplicable a escala técnica para la separacion dinámica entre enantiomeros de derivados de piperidona con la formula general (1) en la que R1, R2, R3 y n pueden tener los significados mencionados en la memoria descriptiva y en las reivindicaciones, mediando simultánea racemizacion in situ del enantiomero que no haya reaccionado.The invention relates to a method applicable on a technical scale for the dynamic separation between enantiomers of piperidone derivatives with the general formula (1) in which R1, R2, R3 and n can have the meanings mentioned in the specification and in the claims , simultaneously mediating in situ racemization of the enantiomer that has not reacted.

ARP010102869A 2000-06-16 2001-06-15 SEPARATION BETWEEN DWELLERS OF PIPERIDONE DERIVATIVES WITH SIMULATE NEA RACEMIZATION IN SITU OF INDENATED ENANTIUM Suspension/Interruption AR028957A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10029851A DE10029851A1 (en) 2000-06-16 2000-06-16 Optical resolution of 2-substituted 4-piperidone derivatives, for use as pharmaceutical intermediates, by simultaneous formation of salt with optically active acid and racemization

Publications (1)

Publication Number Publication Date
AR028957A1 true AR028957A1 (en) 2003-05-28

Family

ID=7646064

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP010102869A Suspension/Interruption AR028957A1 (en) 2000-06-16 2001-06-15 SEPARATION BETWEEN DWELLERS OF PIPERIDONE DERIVATIVES WITH SIMULATE NEA RACEMIZATION IN SITU OF INDENATED ENANTIUM

Country Status (10)

Country Link
EP (1) EP1305287A1 (en)
JP (1) JP2004503539A (en)
KR (1) KR100863922B1 (en)
AR (1) AR028957A1 (en)
AU (1) AU2001270563A1 (en)
CA (1) CA2409614C (en)
DE (1) DE10029851A1 (en)
IL (2) IL153085A0 (en)
MX (1) MXPA02012301A (en)
WO (1) WO2001096306A1 (en)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0736724B2 (en) * 1992-08-07 1995-04-26 株式会社スリオンテック Seeding and raising seedling sheet using ultraviolet curing adhesive and method for producing the same
ES2173194T3 (en) * 1994-09-23 2002-10-16 Darwin Discovery Ltd PROCEDURE OF RACEMIZATION USED FOR THE PREPARATION OF LEVOBUPIVACAINE AND ITS ANALOGS.
DE19528472A1 (en) * 1995-08-03 1997-02-06 Boehringer Ingelheim Kg New process for the production of norbenzomorphan of an intermediate stage in the production of pharmaceutically valuable benzomorphan derivatives, in particular of (-) - (1R, 5S, S "R) -3'-hydroxy-2- (2-methoxypropyl -) - 5.9.9 -trimethyl-6.7 benzomorphan

Also Published As

Publication number Publication date
MXPA02012301A (en) 2003-04-25
AU2001270563A1 (en) 2001-12-24
EP1305287A1 (en) 2003-05-02
WO2001096306A1 (en) 2001-12-20
JP2004503539A (en) 2004-02-05
DE10029851A1 (en) 2001-12-20
CA2409614C (en) 2008-08-05
IL153085A (en) 2008-11-26
KR100863922B1 (en) 2008-10-17
IL153085A0 (en) 2003-06-24
CA2409614A1 (en) 2001-12-20
KR20030016288A (en) 2003-02-26

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