AR026834A1 - Benzosulfonas y composiciones y metodos relacionados. - Google Patents

Benzosulfonas y composiciones y metodos relacionados.

Info

Publication number
AR026834A1
AR026834A1 ARP010100125A ARP010100125A AR026834A1 AR 026834 A1 AR026834 A1 AR 026834A1 AR P010100125 A ARP010100125 A AR P010100125A AR P010100125 A ARP010100125 A AR P010100125A AR 026834 A1 AR026834 A1 AR 026834A1
Authority
AR
Argentina
Prior art keywords
disorders
cardiovascular
compositions
benzosulphones
related methods
Prior art date
Application number
ARP010100125A
Other languages
English (en)
Original Assignee
Ortho Mcneil Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho Mcneil Pharm Inc filed Critical Ortho Mcneil Pharm Inc
Publication of AR026834A1 publication Critical patent/AR026834A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/06—Antiabortive agents; Labour repressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Immunology (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pregnancy & Childbirth (AREA)
  • Diabetes (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

Provee novedosas benzosulfonas de las formulas 1 y 2. Dichos compuestos son utiles como antagonistas de los canales de calcio, con una catividadcardiovascular, antiasmática y anti-broncoconstriccion. En virtud de ello, la presente invencion provee co mposiciones farmacéuticas, como también métodos, paraprevenir y tratar trastornos tales como la hipersensibilidad, alergia, asma, espasmos bronquiales, dismenorrea, espasmos del esofago, glaucoma, parto prematurotrastornos del tracto urinario, trasto rnos de la motilidad gastroitestinal y trastornos cardiovasculares. Los sustituyentes R1 a R8 están definidos en lamemoria descriptiva.
ARP010100125A 2000-01-12 2001-01-12 Benzosulfonas y composiciones y metodos relacionados. AR026834A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17565000P 2000-01-12 2000-01-12
US09/751,005 US6410553B1 (en) 2000-01-12 2000-12-28 Benzosulfones and related compositions and methods

Publications (1)

Publication Number Publication Date
AR026834A1 true AR026834A1 (es) 2003-02-26

Family

ID=22641084

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP010100125A AR026834A1 (es) 2000-01-12 2001-01-12 Benzosulfonas y composiciones y metodos relacionados.

Country Status (14)

Country Link
US (1) US6410553B1 (es)
EP (1) EP1246828B1 (es)
JP (1) JP2003519626A (es)
CN (1) CN1301997C (es)
AR (1) AR026834A1 (es)
AT (1) ATE312106T1 (es)
AU (1) AU783470B2 (es)
CA (1) CA2396962A1 (es)
DE (1) DE60024675T2 (es)
DK (1) DK1246828T3 (es)
ES (1) ES2254258T3 (es)
MX (1) MXPA02006842A (es)
MY (1) MY128383A (es)
WO (1) WO2001051493A1 (es)

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4483985A (en) 1978-10-31 1984-11-20 Bayer Aktiengesellschaft Production of 1,4-dihydropyridinecarboxylic acids
US4285955A (en) 1978-10-31 1981-08-25 Bayer Aktiengesellschaft 1,4-Dihydropyridinecarboxylic acids
NZ201395A (en) 1981-07-30 1987-02-20 Bayer Ag Pharmaceutical compositions containing 1,4-dihydropyridines and certain of these dihydropyridines
US4705785A (en) * 1986-04-09 1987-11-10 Ortho Pharmaceutical Corporation Substituted thiacycloalkeno (3,2-b) pyridines and pharmaceutical compositions and method of use
US4845225A (en) 1986-04-09 1989-07-04 Ortho Pharmaceutical Corporation Substituted thiacycloalkeno [3,2-b] pyridines
US4879384A (en) 1988-06-15 1989-11-07 Ortho Pharmaceutical Corporation Preparation of thiocycloalkno [3,2-b] pyridines
US5075440A (en) * 1990-05-03 1991-12-24 Ortho Pharmaceutical Corporation Novel pyrido[2,3-f](1,4)thiazepines and pyrido[3,2-b](1,5)benzothiazepines
DE19532320A1 (de) 1995-09-01 1997-03-06 Bayer Ag Verfahren zur Herstellung von optisch aktiven ortho-substituierten 4-Aryl-Dihydropyridinen
JP2003502335A (ja) 1999-06-14 2003-01-21 オーソ−マクニール・フアーマシユーチカル・インコーポレーテツド ジチエピノ［６，５−ｂ］ピリジンおよび関連組成物および方法

Also Published As

Publication number Publication date
WO2001051493A1 (en) 2001-07-19
JP2003519626A (ja) 2003-06-24
US6410553B1 (en) 2002-06-25
ES2254258T3 (es) 2006-06-16
DE60024675D1 (de) 2006-01-12
ATE312106T1 (de) 2005-12-15
AU2462401A (en) 2001-07-24
CN1451010A (zh) 2003-10-22
EP1246828B1 (en) 2005-12-07
US20020049326A1 (en) 2002-04-25
CA2396962A1 (en) 2001-07-19
MXPA02006842A (es) 2004-04-05
CN1301997C (zh) 2007-02-28
MY128383A (en) 2007-01-31
DK1246828T3 (da) 2006-04-03
DE60024675T2 (de) 2006-08-24
EP1246828A1 (en) 2002-10-09
AU783470B2 (en) 2005-10-27

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Legal Events

Date Code Title Description
FA Abandonment or withdrawal