AR024577A1 - NEW USEFUL BISPIDINE COMPOUNDS IN THE CARDIAC ARRITMIAS TREATMENT - Google Patents
NEW USEFUL BISPIDINE COMPOUNDS IN THE CARDIAC ARRITMIAS TREATMENTInfo
- Publication number
- AR024577A1 AR024577A1 ARP000103015A ARP000103015A AR024577A1 AR 024577 A1 AR024577 A1 AR 024577A1 AR P000103015 A ARP000103015 A AR P000103015A AR P000103015 A ARP000103015 A AR P000103015A AR 024577 A1 AR024577 A1 AR 024577A1
- Authority
- AR
- Argentina
- Prior art keywords
- treatment
- arritmias
- cardiac
- new useful
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/08—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Cardiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Heart & Thoracic Surgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
Se proveen compuestos de formula 1 en la cual R1,R2, R3, R4, R5, R6, R7 R41, R42, R43, R44, R45, R46, Ay B tienen los significados proporcionados en ladescripcion, los cuales son utiles en la profilaxis y en el tratamiento de arritmias en particulararritmias de atrios y ventriculares.Compounds of formula 1 are provided in which R1, R2, R3, R4, R5, R6, R7 R41, R42, R43, R44, R45, R46, A and B have the meanings provided in the description, which are useful in prophylaxis and in the treatment of arrhythmias in atrial and ventricular particular arrhythmias.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9902268A SE9902268D0 (en) | 1999-06-16 | 1999-06-16 | Pharmaceutically active compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR024577A1 true AR024577A1 (en) | 2002-10-16 |
Family
ID=20416100
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP000103015A AR024577A1 (en) | 1999-06-16 | 2000-06-16 | NEW USEFUL BISPIDINE COMPOUNDS IN THE CARDIAC ARRITMIAS TREATMENT |
Country Status (24)
| Country | Link |
|---|---|
| EP (1) | EP1192157A1 (en) |
| JP (1) | JP2003502329A (en) |
| KR (1) | KR20020010713A (en) |
| CN (1) | CN1144805C (en) |
| AR (1) | AR024577A1 (en) |
| AU (1) | AU761576B2 (en) |
| BR (1) | BR0011660A (en) |
| CA (1) | CA2375841A1 (en) |
| CZ (1) | CZ20014495A3 (en) |
| EE (1) | EE200100675A (en) |
| HK (1) | HK1045520A1 (en) |
| HU (1) | HUP0203959A3 (en) |
| IL (1) | IL146754A0 (en) |
| IS (1) | IS6201A (en) |
| MX (1) | MXPA01012919A (en) |
| NO (1) | NO20016117L (en) |
| NZ (1) | NZ516013A (en) |
| PL (1) | PL354032A1 (en) |
| RU (1) | RU2250903C2 (en) |
| SE (1) | SE9902268D0 (en) |
| SK (1) | SK18272001A3 (en) |
| TR (1) | TR200103663T2 (en) |
| WO (1) | WO2000077000A1 (en) |
| ZA (1) | ZA200109796B (en) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR030302A1 (en) * | 2000-07-07 | 2003-08-20 | Astrazeneca Ab | BISPIDINE COMPOUNDS, PHARMACEUTICAL FORMULATION, USE FOR THE MANUFACTURE OF MEDICINES, PROCESS FOR THE PREPARATION OF THESE INTERMEDIATE COMPOUNDS AND COMPOUNDS |
| SE0101327D0 (en) | 2001-04-12 | 2001-04-12 | Astrazeneca Ab | New crystalline forms |
| TWI499418B (en) * | 2009-05-21 | 2015-09-11 | Nerviano Medical Sciences Srl | Isoquinolin-1(2h)-one derivatives |
| WO2013007603A1 (en) * | 2011-07-08 | 2013-01-17 | Bayer Intellectual Property Gmbh | Method for the production of 2-amino-5-cyano-n,3-dimethylbenzamide |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT88381B (en) * | 1987-09-09 | 1995-07-06 | Kali Chemie Pharma Gmbh | PROCESS FOR THE PREPARATION OF NEW COMPOUNDS 3,7-DIAZABICYCLO (3,3,1) NONANO, AND OF PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS |
| DE3732094A1 (en) * | 1987-09-24 | 1989-04-06 | Basf Ag | BISPID DERIVATIVES AS CLASS III ANTIARRHYTHMICS |
| US5110933A (en) * | 1989-11-13 | 1992-05-05 | Board Of Regents Of Oklahoma State University | Salts of 3-azabicyclo[3.3.1]nonanes as antiarrhythmic agents, and precursors thereof |
| US5468858A (en) * | 1993-10-28 | 1995-11-21 | The Board Of Regents Of Oklahoma State University Physical Sciences | N-alkyl and n-acyl derivatives of 3,7-diazabicyclo-[3.3.1]nonanes and selected salts thereof as multi-class antiarrhythmic agents |
| SE9704709D0 (en) * | 1997-12-17 | 1997-12-17 | Astra Ab | Pharmaceutically active compounds |
-
1999
- 1999-06-16 SE SE9902268A patent/SE9902268D0/en unknown
-
2000
- 2000-06-15 NZ NZ516013A patent/NZ516013A/en unknown
- 2000-06-15 WO PCT/SE2000/001254 patent/WO2000077000A1/en not_active Application Discontinuation
- 2000-06-15 CA CA002375841A patent/CA2375841A1/en not_active Abandoned
- 2000-06-15 RU RU2001132563/04A patent/RU2250903C2/en not_active IP Right Cessation
- 2000-06-15 AU AU60324/00A patent/AU761576B2/en not_active Ceased
- 2000-06-15 SK SK1827-2001A patent/SK18272001A3/en unknown
- 2000-06-15 CN CNB008116962A patent/CN1144805C/en not_active Expired - Fee Related
- 2000-06-15 PL PL00354032A patent/PL354032A1/en not_active Application Discontinuation
- 2000-06-15 EE EEP200100675A patent/EE200100675A/en unknown
- 2000-06-15 TR TR2001/03663T patent/TR200103663T2/en unknown
- 2000-06-15 BR BR0011660-2A patent/BR0011660A/en not_active IP Right Cessation
- 2000-06-15 MX MXPA01012919A patent/MXPA01012919A/en unknown
- 2000-06-15 EP EP00946589A patent/EP1192157A1/en not_active Withdrawn
- 2000-06-15 CZ CZ20014495A patent/CZ20014495A3/en unknown
- 2000-06-15 IL IL14675400A patent/IL146754A0/en unknown
- 2000-06-15 HU HU0203959A patent/HUP0203959A3/en unknown
- 2000-06-15 KR KR1020017016168A patent/KR20020010713A/en not_active Application Discontinuation
- 2000-06-15 JP JP2001503858A patent/JP2003502329A/en active Pending
- 2000-06-16 AR ARP000103015A patent/AR024577A1/en not_active Application Discontinuation
-
2001
- 2001-11-28 ZA ZA200109796A patent/ZA200109796B/en unknown
- 2001-12-14 IS IS6201A patent/IS6201A/en unknown
- 2001-12-14 NO NO20016117A patent/NO20016117L/en not_active Application Discontinuation
-
2002
- 2002-09-27 HK HK02107165.2A patent/HK1045520A1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN1370167A (en) | 2002-09-18 |
| NO20016117D0 (en) | 2001-12-14 |
| WO2000077000A1 (en) | 2000-12-21 |
| HK1045520A1 (en) | 2002-11-29 |
| JP2003502329A (en) | 2003-01-21 |
| AU761576B2 (en) | 2003-06-05 |
| IL146754A0 (en) | 2002-07-25 |
| ZA200109796B (en) | 2003-02-28 |
| CZ20014495A3 (en) | 2002-05-15 |
| NZ516013A (en) | 2003-06-30 |
| SK18272001A3 (en) | 2002-12-03 |
| KR20020010713A (en) | 2002-02-04 |
| CN1144805C (en) | 2004-04-07 |
| HUP0203959A2 (en) | 2003-03-28 |
| SE9902268D0 (en) | 1999-06-16 |
| RU2250903C2 (en) | 2005-04-27 |
| EP1192157A1 (en) | 2002-04-03 |
| TR200103663T2 (en) | 2002-05-21 |
| AU6032400A (en) | 2001-01-02 |
| IS6201A (en) | 2001-12-14 |
| BR0011660A (en) | 2002-03-26 |
| CA2375841A1 (en) | 2000-12-21 |
| EE200100675A (en) | 2003-02-17 |
| HUP0203959A3 (en) | 2003-04-28 |
| PL354032A1 (en) | 2003-12-15 |
| WO2000077000A9 (en) | 2003-06-19 |
| MXPA01012919A (en) | 2002-07-30 |
| NO20016117L (en) | 2002-02-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |