UY28201A1 - USEFUL TRIAZOL COMPOUNDS IN THERAPY - Google Patents
USEFUL TRIAZOL COMPOUNDS IN THERAPYInfo
- Publication number
- UY28201A1 UY28201A1 UY28201A UY28201A UY28201A1 UY 28201 A1 UY28201 A1 UY 28201A1 UY 28201 A UY28201 A UY 28201A UY 28201 A UY28201 A UY 28201A UY 28201 A1 UY28201 A1 UY 28201A1
- Authority
- UY
- Uruguay
- Prior art keywords
- useful
- therapy
- compounds
- triazol
- triazol compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Hospice & Palliative Care (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
COMPUESTOS DE TRIAZOL ÚTILES EN TERAPIA Un compuesto de fórmula (1) O un derivado farmacéuticamente aceptable del mismo, en el que U, W, R, X, Y, Z, A, B, R, R,R, son como se definieron en la memoria descriptiva y en el capítulo reivindicatorio, siendo dichos compuestos útiles en el tratamiento de la dismenorrea.USEFUL TRIAZOL COMPOUNDS IN THERAPY A compound of formula (1) Or a pharmaceutically acceptable derivative thereof, in which U, W, R, X, Y, Z, A, B, R, R, R, are as defined in the specification and in the claim chapter, said compounds being useful in the treatment of dysmenorrhea.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0303852.8A GB0303852D0 (en) | 2003-02-19 | 2003-02-19 | Triazole compounds useful in therapy |
Publications (1)
Publication Number | Publication Date |
---|---|
UY28201A1 true UY28201A1 (en) | 2004-09-30 |
Family
ID=9953327
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
UY28201A UY28201A1 (en) | 2003-02-19 | 2004-02-19 | USEFUL TRIAZOL COMPOUNDS IN THERAPY |
Country Status (11)
Country | Link |
---|---|
CN (1) | CN1751047A (en) |
AR (1) | AR043210A1 (en) |
CL (1) | CL2004000293A1 (en) |
GB (1) | GB0303852D0 (en) |
GT (1) | GT200400020A (en) |
NL (1) | NL1025527C2 (en) |
PA (1) | PA8596101A1 (en) |
PE (1) | PE20050222A1 (en) |
TW (1) | TW200500367A (en) |
UY (1) | UY28201A1 (en) |
WO (1) | WO2004074291A1 (en) |
Families Citing this family (42)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0325021D0 (en) * | 2003-10-27 | 2003-12-03 | Pfizer Ltd | Therapeutic combinations |
US7745630B2 (en) | 2003-12-22 | 2010-06-29 | Justin Stephen Bryans | Triazolyl piperidine arginine vasopressin receptor modulators |
DE102004001871A1 (en) * | 2004-01-14 | 2005-09-01 | Bayer Healthcare Ag | Tricyclic benzazepine derivatives and their use |
MX2007002248A (en) * | 2004-08-25 | 2008-10-02 | Pfizer | Triazolobenzodiazepines and their use as vasopressin antagonists. |
EP1877399A1 (en) * | 2005-04-26 | 2008-01-16 | Pfizer Limited | Triazole derivatives as vasopressin antagonists |
MX2011004575A (en) | 2008-11-13 | 2011-06-01 | Hoffmann La Roche | Spiro-5,6-dihydro-4h-2,3,5,10b-tetraaza-benzo[e]azulenes. |
JP5384659B2 (en) * | 2008-11-18 | 2014-01-08 | エフ.ホフマン−ラ ロシュ アーゲー | Alkylcyclohexyl ether of dihydrotetraazabenzoazulene |
MY150837A (en) | 2008-11-28 | 2014-02-28 | Hoffmann La Roche | Arylcyclohexylethers of dihydrotetraazabenzoazulenes for use as vasopressin via receptor antagonists |
EP2414361A1 (en) | 2009-03-31 | 2012-02-08 | ArQule, Inc. | Substituted heterocyclic compounds |
JP2013510834A (en) * | 2009-11-16 | 2013-03-28 | メリテク | [1,5] -diazocine derivatives |
US8420633B2 (en) | 2010-03-31 | 2013-04-16 | Hoffmann-La Roche Inc. | Aryl-cyclohexyl-tetraazabenzo[e]azulenes |
US8461151B2 (en) | 2010-04-13 | 2013-06-11 | Hoffmann-La Roche Inc. | Aryl-/heteroaryl-cyclohexenyl-tetraazabenzo[e]azulenes |
US8492376B2 (en) * | 2010-04-21 | 2013-07-23 | Hoffmann-La Roche Inc. | Heteroaryl-cyclohexyl-tetraazabenzo[e]azulenes |
US8481528B2 (en) * | 2010-04-26 | 2013-07-09 | Hoffmann-La Roche Inc. | Heterobiaryl-cyclohexyl-tetraazabenzo[e]azulenes |
US8513238B2 (en) * | 2010-05-10 | 2013-08-20 | Hoffmann-La Roche Inc. | Heteroaryl-cyclohexyl-tetraazabenzo[E]azulenes |
US9006450B2 (en) * | 2010-07-01 | 2015-04-14 | Boehringer Ingelheim International Gmbh | Compounds, pharmaceutical compositions and uses thereof |
TW201242956A (en) | 2010-10-07 | 2012-11-01 | Takeda Pharmaceutical | Heterocyclic compounds |
RU2011122942A (en) | 2011-06-08 | 2012-12-20 | Общество С Ограниченной Ответственностью "Асинэкс Медхим" | NEW KINAZ INHIBITORS |
US8828989B2 (en) * | 2011-09-26 | 2014-09-09 | Hoffmann-La Roche Inc. | Oxy-cyclohexyl-4H,6H-5-oxa-2,3,10b-triaza-benzo[E]azulenes as V1A antagonists |
BR112014007851A2 (en) | 2011-10-05 | 2017-04-18 | Hoffmann La Roche | cyclohexyl-4h, 6h-oxa-2,3,10b-triaza-benzo [e] azulenes as v1a antagonists |
HUE030526T2 (en) | 2012-06-13 | 2017-05-29 | Hoffmann La Roche | New diazaspirocycloalkane and azaspirocycloalkane |
CN102766674A (en) * | 2012-07-25 | 2012-11-07 | 辉源生物科技(上海)有限公司 | Establishment of screening platform for cynomolgus monkey antidiuretic hormone receptor V1A antagonist |
SG11201500572YA (en) | 2012-09-25 | 2015-02-27 | Hoffmann La Roche | New bicyclic derivatives |
AR095079A1 (en) | 2013-03-12 | 2015-09-16 | Hoffmann La Roche | DERIVATIVES OF OCTAHIDRO-PIRROLO [3,4-C] -PIRROL AND PIRIDINA-FENILO |
EA201690179A1 (en) | 2013-08-19 | 2016-06-30 | Ф. Хоффманн-Ля Рош Аг | V1A RECEPTOR ANTAGONISTS FOR TREATMENT OF DISORDERS ASSOCIATED WITH SHEEP PHASE SHIFT |
EA201691044A1 (en) | 2013-11-26 | 2016-09-30 | Ф. Хоффманн-Ля Рош Аг | NEW OCTAGIDRO-CYCLOBUT [1,2-C; 3,4-C '] DIPIRROL-2-IL |
PL3077396T3 (en) | 2013-12-05 | 2021-10-04 | F. Hoffmann-La Roche Ag | Synthesis of trans-8-chloro-5-methyl-1 -[4-(pyridin-2-yloxy)-cyclohexyl]-5,6-dihydro-4h-2,3,5,10b-tetraaza-benzo[e]azulene and crytalline forms thereof |
UA119347C2 (en) | 2014-03-26 | 2019-06-10 | Ф. Хоффманн-Ля Рош Аг | Condensed [1,4]diazepine compounds as autotaxin (atx) and lysophosphatidic acid (lpa) production inhibitors |
LT3122750T (en) | 2014-03-26 | 2019-11-11 | Hoffmann La Roche | Bicyclic compounds as autotaxin (atx) and lysophosphatidic acid (lpa) production inhibitors |
MA41898A (en) | 2015-04-10 | 2018-02-13 | Hoffmann La Roche | BICYCLIC QUINAZOLINONE DERIVATIVES |
CN108026077B (en) | 2015-09-04 | 2021-11-05 | 豪夫迈·罗氏有限公司 | Phenoxymethyl derivatives |
CR20180143A (en) | 2015-09-24 | 2018-05-03 | Hoffmann La Roche | NEW BICYCLE COMPOUNDS AS DUAL INHIBITORS OF ATX / CA |
KR20180054635A (en) | 2015-09-24 | 2018-05-24 | 에프. 호프만-라 로슈 아게 | As an autotaxin (ATX) inhibitor, |
RU2724899C2 (en) | 2015-09-24 | 2020-06-26 | Ф. Хоффманн-Ля Рош Аг | New bicyclic compounds as dual inhibitors of atx/ca |
MA42918A (en) | 2015-09-24 | 2018-08-01 | Hoffmann La Roche | BICYCLIC COMPOUNDS USED AS ATX INHIBITORS |
KR20190129924A (en) | 2017-03-16 | 2019-11-20 | 에프. 호프만-라 로슈 아게 | Heterocyclic Compounds Useful as Dual Autotaxin (ATX) / Carbon Anhydrase (CA) Inhibitors |
EP3596060B1 (en) | 2017-03-16 | 2023-09-20 | F. Hoffmann-La Roche AG | New bicyclic compounds as atx inhibitors |
US11186577B2 (en) * | 2017-06-05 | 2021-11-30 | Blackthorn Therapeutics, Inc. | Vasopressin receptor antagonists and products and methods related thereto |
TW201938171A (en) | 2017-12-15 | 2019-10-01 | 匈牙利商羅特格登公司 | Tricyclic compounds as vasopressin V1a receptor antagonists |
HU231206B1 (en) * | 2017-12-15 | 2021-10-28 | Richter Gedeon Nyrt. | Triazolobenzazepines |
CN111170983B (en) * | 2019-12-26 | 2021-07-09 | 中国农业大学 | Benzylthio acetamide compound and preparation method and application thereof |
TWI804119B (en) * | 2020-12-21 | 2023-06-01 | 大陸商上海濟煜醫藥科技有限公司 | Derivative of triazole fused three rings, manufacturing method and use thereof |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8823475D0 (en) * | 1988-10-06 | 1988-11-16 | Merck Sharp & Dohme | Chemical compounds |
US5438035A (en) * | 1994-06-24 | 1995-08-01 | American Cyanamid Company | Methods for controlling undesirable plant species with benzodiazepine compounds |
US5753648A (en) * | 1995-01-17 | 1998-05-19 | American Cyanamid Company | Tricyclic benzazepine vasopressin antagonists |
EP1021444B1 (en) * | 1996-11-01 | 2003-09-24 | Wyeth | 3-CARBOXAMIDE DERIVATIVES OF 5H-PYRROLO[2,1-c][1,4]-BENZODIAZEPINES |
AU772397B2 (en) * | 1999-01-19 | 2004-04-29 | Ortho-Mcneil Pharmaceutical, Inc. | Tricyclic benzodiazepines as vasopressin receptor antagonists |
US7109193B2 (en) * | 2001-04-12 | 2006-09-19 | Wyeth | Tricyclic diazepines tocolytic oxytocin receptor antagonists |
-
2003
- 2003-02-19 GB GBGB0303852.8A patent/GB0303852D0/en not_active Ceased
-
2004
- 2004-02-09 WO PCT/IB2004/000432 patent/WO2004074291A1/en active IP Right Grant
- 2004-02-09 CN CNA2004800047089A patent/CN1751047A/en active Pending
- 2004-02-17 PE PE2004000165A patent/PE20050222A1/en not_active Application Discontinuation
- 2004-02-18 CL CL200400293A patent/CL2004000293A1/en unknown
- 2004-02-18 TW TW093103978A patent/TW200500367A/en unknown
- 2004-02-18 GT GT200400020A patent/GT200400020A/en unknown
- 2004-02-18 AR ARP040100495A patent/AR043210A1/en not_active Application Discontinuation
- 2004-02-18 PA PA20048596101A patent/PA8596101A1/en unknown
- 2004-02-19 UY UY28201A patent/UY28201A1/en unknown
- 2004-02-19 NL NL1025527A patent/NL1025527C2/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
PE20050222A1 (en) | 2005-04-13 |
AR043210A1 (en) | 2005-07-20 |
GT200400020A (en) | 2004-09-21 |
PA8596101A1 (en) | 2005-08-04 |
WO2004074291A1 (en) | 2004-09-02 |
CL2004000293A1 (en) | 2005-01-07 |
NL1025527C2 (en) | 2005-03-14 |
CN1751047A (en) | 2006-03-22 |
GB0303852D0 (en) | 2003-03-26 |
NL1025527A1 (en) | 2004-08-23 |
TW200500367A (en) | 2005-01-01 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
UY28201A1 (en) | USEFUL TRIAZOL COMPOUNDS IN THERAPY | |
ECSP044992A (en) | INHIBITORS OF THE ALQUÍN-ARIL FOSFODIESTERASA-4 | |
PA8556201A1 (en) | ALKINS AS MATRIX METALOPROTEINASE INHIBITORS | |
ECSP055863A (en) | PYRIDODIACINS AS FUNGUICIDES OF PLANTS | |
PA8571001A1 (en) | 2- (2,6-DICLOROPHENYL) -DIARYLIMIDAZOLS | |
CY1106958T1 (en) | N-ALKYLO-4-MYTHYLENAMINE-3-HYDROXY-2-PYRIDONES AS ANTIMICROBIAL | |
GEP20053692B (en) | Substituted Alkylamine Derivatives and Methods of Use | |
CR8481A (en) | TRIAZOL DERIVATIVES AS VASOPRESINE ANTAGONISTS | |
CY1109385T1 (en) | GRAIN SUSPENSIONS AND THEIR USES | |
PA8509301A1 (en) | NON-PEPTIDIC INHIBITORS OF THE VLA-4 DEPENDENT CELL UNION IN INFLAMMATORY, AUTO-IMMUNE AND RESPIRATORY DISEASES | |
CO5700767A2 (en) | TRANSPLANT REJECTION TREATMENT PROCEDURE | |
BRPI0411897A (en) | pyrroldhydroisoquinolines as pde10 inhibitors | |
CY1109240T1 (en) | A combination of Valsartan, Amlodipine and Hydrochlorothiazide | |
BG105784A (en) | Triazole compounds with dopamine-d3-receptor affinity | |
UY26380A1 (en) | FAB I INHIBITORS | |
NO20062256L (en) | Hydroxyalkyl-substituted pyrido-7-pyrimidin-7-ones | |
NO331012B1 (en) | N-sulfonyl-4-methyleneamino-3-hydroxy-2-pyridones as antimicrobial agents | |
BRPI0519267A2 (en) | quinoline derivative, its use, production and medicine containing the same | |
HK1076812A1 (en) | Cyanoguanidine prodrugs | |
ECSP088484A (en) | SPIROCYCLIC QUINAZOLINE DERIVATIVES AS PDE7 INHIBITORS | |
ATE516031T1 (en) | COMPOUNDS AGAINST CANCER | |
NO20044548L (en) | Process for the preparation of 6-alkalidene-penem derivatives | |
UY27451A1 (en) | 2,5-DIAMIDOINDOLES REPLACED AND ITS USE | |
UY28485A1 (en) | CHEMICAL COMPOUNDS | |
NO20053562L (en) | Novel aminobenzophenone compounds |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
DESI | Application deemed to be withdrawn |
Effective date: 20140310 |