UY28201A1 - USEFUL TRIAZOL COMPOUNDS IN THERAPY - Google Patents

USEFUL TRIAZOL COMPOUNDS IN THERAPY

Info

Publication number
UY28201A1
UY28201A1 UY28201A UY28201A UY28201A1 UY 28201 A1 UY28201 A1 UY 28201A1 UY 28201 A UY28201 A UY 28201A UY 28201 A UY28201 A UY 28201A UY 28201 A1 UY28201 A1 UY 28201A1
Authority
UY
Uruguay
Prior art keywords
useful
therapy
compounds
triazol
triazol compounds
Prior art date
Application number
UY28201A
Other languages
Spanish (es)
Inventor
Justin Stephen Bryans
Thomas Ryckmans
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of UY28201A1 publication Critical patent/UY28201A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Hospice & Palliative Care (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

COMPUESTOS DE TRIAZOL ÚTILES EN TERAPIA Un compuesto de fórmula (1) O un derivado farmacéuticamente aceptable del mismo, en el que U, W, R, X, Y, Z, A, B, R, R,R, son como se definieron en la memoria descriptiva y en el capítulo reivindicatorio, siendo dichos compuestos útiles en el tratamiento de la dismenorrea.USEFUL TRIAZOL COMPOUNDS IN THERAPY A compound of formula (1) Or a pharmaceutically acceptable derivative thereof, in which U, W, R, X, Y, Z, A, B, R, R, R, are as defined in the specification and in the claim chapter, said compounds being useful in the treatment of dysmenorrhea.

UY28201A 2003-02-19 2004-02-19 USEFUL TRIAZOL COMPOUNDS IN THERAPY UY28201A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0303852.8A GB0303852D0 (en) 2003-02-19 2003-02-19 Triazole compounds useful in therapy

Publications (1)

Publication Number Publication Date
UY28201A1 true UY28201A1 (en) 2004-09-30

Family

ID=9953327

Family Applications (1)

Application Number Title Priority Date Filing Date
UY28201A UY28201A1 (en) 2003-02-19 2004-02-19 USEFUL TRIAZOL COMPOUNDS IN THERAPY

Country Status (11)

Country Link
CN (1) CN1751047A (en)
AR (1) AR043210A1 (en)
CL (1) CL2004000293A1 (en)
GB (1) GB0303852D0 (en)
GT (1) GT200400020A (en)
NL (1) NL1025527C2 (en)
PA (1) PA8596101A1 (en)
PE (1) PE20050222A1 (en)
TW (1) TW200500367A (en)
UY (1) UY28201A1 (en)
WO (1) WO2004074291A1 (en)

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GB0325021D0 (en) * 2003-10-27 2003-12-03 Pfizer Ltd Therapeutic combinations
US7745630B2 (en) 2003-12-22 2010-06-29 Justin Stephen Bryans Triazolyl piperidine arginine vasopressin receptor modulators
DE102004001871A1 (en) * 2004-01-14 2005-09-01 Bayer Healthcare Ag Tricyclic benzazepine derivatives and their use
MX2007002248A (en) * 2004-08-25 2008-10-02 Pfizer Triazolobenzodiazepines and their use as vasopressin antagonists.
EP1877399A1 (en) * 2005-04-26 2008-01-16 Pfizer Limited Triazole derivatives as vasopressin antagonists
MX2011004575A (en) 2008-11-13 2011-06-01 Hoffmann La Roche Spiro-5,6-dihydro-4h-2,3,5,10b-tetraaza-benzo[e]azulenes.
JP5384659B2 (en) * 2008-11-18 2014-01-08 エフ．ホフマン−ラ ロシュ アーゲー Alkylcyclohexyl ether of dihydrotetraazabenzoazulene
MY150837A (en) 2008-11-28 2014-02-28 Hoffmann La Roche Arylcyclohexylethers of dihydrotetraazabenzoazulenes for use as vasopressin via receptor antagonists
EP2414361A1 (en) 2009-03-31 2012-02-08 ArQule, Inc. Substituted heterocyclic compounds
JP2013510834A (en) * 2009-11-16 2013-03-28 メリテク [1,5] -diazocine derivatives
US8420633B2 (en) 2010-03-31 2013-04-16 Hoffmann-La Roche Inc. Aryl-cyclohexyl-tetraazabenzo[e]azulenes
US8461151B2 (en) 2010-04-13 2013-06-11 Hoffmann-La Roche Inc. Aryl-/heteroaryl-cyclohexenyl-tetraazabenzo[e]azulenes
US8492376B2 (en) * 2010-04-21 2013-07-23 Hoffmann-La Roche Inc. Heteroaryl-cyclohexyl-tetraazabenzo[e]azulenes
US8481528B2 (en) * 2010-04-26 2013-07-09 Hoffmann-La Roche Inc. Heterobiaryl-cyclohexyl-tetraazabenzo[e]azulenes
US8513238B2 (en) * 2010-05-10 2013-08-20 Hoffmann-La Roche Inc. Heteroaryl-cyclohexyl-tetraazabenzo[E]azulenes
US9006450B2 (en) * 2010-07-01 2015-04-14 Boehringer Ingelheim International Gmbh Compounds, pharmaceutical compositions and uses thereof
TW201242956A (en) 2010-10-07 2012-11-01 Takeda Pharmaceutical Heterocyclic compounds
RU2011122942A (en) 2011-06-08 2012-12-20 Общество С Ограниченной Ответственностью "Асинэкс Медхим" NEW KINAZ INHIBITORS
US8828989B2 (en) * 2011-09-26 2014-09-09 Hoffmann-La Roche Inc. Oxy-cyclohexyl-4H,6H-5-oxa-2,3,10b-triaza-benzo[E]azulenes as V1A antagonists
BR112014007851A2 (en) 2011-10-05 2017-04-18 Hoffmann La Roche cyclohexyl-4h, 6h-oxa-2,3,10b-triaza-benzo [e] azulenes as v1a antagonists
HUE030526T2 (en) 2012-06-13 2017-05-29 Hoffmann La Roche New diazaspirocycloalkane and azaspirocycloalkane
CN102766674A (en) * 2012-07-25 2012-11-07 辉源生物科技（上海）有限公司 Establishment of screening platform for cynomolgus monkey antidiuretic hormone receptor V1A antagonist
SG11201500572YA (en) 2012-09-25 2015-02-27 Hoffmann La Roche New bicyclic derivatives
AR095079A1 (en) 2013-03-12 2015-09-16 Hoffmann La Roche DERIVATIVES OF OCTAHIDRO-PIRROLO [3,4-C] -PIRROL AND PIRIDINA-FENILO
EA201690179A1 (en) 2013-08-19 2016-06-30 Ф. Хоффманн-Ля Рош Аг V1A RECEPTOR ANTAGONISTS FOR TREATMENT OF DISORDERS ASSOCIATED WITH SHEEP PHASE SHIFT
EA201691044A1 (en) 2013-11-26 2016-09-30 Ф. Хоффманн-Ля Рош Аг NEW OCTAGIDRO-CYCLOBUT [1,2-C; 3,4-C '] DIPIRROL-2-IL
PL3077396T3 (en) 2013-12-05 2021-10-04 F. Hoffmann-La Roche Ag Synthesis of trans-8-chloro-5-methyl-1 -[4-(pyridin-2-yloxy)-cyclohexyl]-5,6-dihydro-4h-2,3,5,10b-tetraaza-benzo[e]azulene and crytalline forms thereof
UA119347C2 (en) 2014-03-26 2019-06-10 Ф. Хоффманн-Ля Рош Аг Condensed [1,4]diazepine compounds as autotaxin (atx) and lysophosphatidic acid (lpa) production inhibitors
LT3122750T (en) 2014-03-26 2019-11-11 Hoffmann La Roche Bicyclic compounds as autotaxin (atx) and lysophosphatidic acid (lpa) production inhibitors
MA41898A (en) 2015-04-10 2018-02-13 Hoffmann La Roche BICYCLIC QUINAZOLINONE DERIVATIVES
CN108026077B (en) 2015-09-04 2021-11-05 豪夫迈·罗氏有限公司 Phenoxymethyl derivatives
CR20180143A (en) 2015-09-24 2018-05-03 Hoffmann La Roche NEW BICYCLE COMPOUNDS AS DUAL INHIBITORS OF ATX / CA
KR20180054635A (en) 2015-09-24 2018-05-24 에프. 호프만-라 로슈 아게 As an autotaxin (ATX) inhibitor,
RU2724899C2 (en) 2015-09-24 2020-06-26 Ф. Хоффманн-Ля Рош Аг New bicyclic compounds as dual inhibitors of atx/ca
MA42918A (en) 2015-09-24 2018-08-01 Hoffmann La Roche BICYCLIC COMPOUNDS USED AS ATX INHIBITORS
KR20190129924A (en) 2017-03-16 2019-11-20 에프. 호프만-라 로슈 아게 Heterocyclic Compounds Useful as Dual Autotaxin (ATX) / Carbon Anhydrase (CA) Inhibitors
EP3596060B1 (en) 2017-03-16 2023-09-20 F. Hoffmann-La Roche AG New bicyclic compounds as atx inhibitors
US11186577B2 (en) * 2017-06-05 2021-11-30 Blackthorn Therapeutics, Inc. Vasopressin receptor antagonists and products and methods related thereto
TW201938171A (en) 2017-12-15 2019-10-01 匈牙利商羅特格登公司 Tricyclic compounds as vasopressin V1a receptor antagonists
HU231206B1 (en) * 2017-12-15 2021-10-28 Richter Gedeon Nyrt. Triazolobenzazepines
CN111170983B (en) * 2019-12-26 2021-07-09 中国农业大学 Benzylthio acetamide compound and preparation method and application thereof
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Also Published As

Publication number Publication date
PE20050222A1 (en) 2005-04-13
AR043210A1 (en) 2005-07-20
GT200400020A (en) 2004-09-21
PA8596101A1 (en) 2005-08-04
WO2004074291A1 (en) 2004-09-02
CL2004000293A1 (en) 2005-01-07
NL1025527C2 (en) 2005-03-14
CN1751047A (en) 2006-03-22
GB0303852D0 (en) 2003-03-26
NL1025527A1 (en) 2004-08-23
TW200500367A (en) 2005-01-01

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Effective date: 20140310