AR024151A1 - Un metodo de profilaxis y tratamiento y agentes utiles para los mismos - Google Patents

Un metodo de profilaxis y tratamiento y agentes utiles para los mismos

Info

Publication number
AR024151A1
AR024151A1 ARP000102652A ARP000102652A AR024151A1 AR 024151 A1 AR024151 A1 AR 024151A1 AR P000102652 A ARP000102652 A AR P000102652A AR P000102652 A ARP000102652 A AR P000102652A AR 024151 A1 AR024151 A1 AR 024151A1
Authority
AR
Argentina
Prior art keywords
heme
porphyrin
infections
treatment
well
Prior art date
Application number
ARP000102652A
Other languages
English (en)
Original Assignee
Univ Sydney
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Sydney filed Critical Univ Sydney
Publication of AR024151A1 publication Critical patent/AR024151A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/12Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1203Gram-negative bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/164Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/41Porphyrin- or corrin-ring-containing peptides
    • A61K38/42Haemoglobins; Myoglobins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/48Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/4873Cysteine endopeptidases (3.4.22), e.g. stem bromelain, papain, ficin, cathepsin H
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/40Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against enzymes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Gynecology & Obstetrics (AREA)
  • Oncology (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La presente se relaciona en general con un método para la profilaxis y tratamiento de la infeccion de microorganismos en medioambientes biologicos desdedonde los microorganismos adquieren hierro, hemo o porfirina, generalmente pero no exclusivamentepara el crecimiento. Los medioambientes biologicosparticulares contemplados por la presente incluyen, pero no se limitan, a regiones vasculares y cavidades, así como también membranas mucosas en animalesincluyendo mamíferos, reptiles, anfibios y peces, y en especies de aves así como también pezunas de animales de ganado. El método de la presente involucrainterrumpir, reducir o de otra forma antagonizar la interaccion entre un polipéptido derivado de microbio, tal como, pero no limitándose a un polipéptido quetiene actividad de proteinasa de cisteína, y una molécula que contiene porfirina, tal como hemo. La presente además proporciona agentes utiles en la profilaxisy tratamiento de la infeccion microbiana de medioambientes biologicos tales como regiones vasculares y cavidades, incluyendo membranas mucosas así como tambiénpezunas que involucran la adquisicion de hierro, hemo o porfirina. Dichos agentes son particularmente utiles como componentes en composiciones terapéuticas.Las infecciones microbianas particularmente importantes apuntadas por la presente involucran infecciones en la cavidad oral, nasofaringe, orofaringe, vagina yuretra en mamíferos tales como humanos. Otras infecciones microbianas importantes incluyen infecciones de las pezunas en animales de ganado tales como ovejas,ganado vacuno y cabras.
ARP000102652A 1999-05-28 2000-05-29 Un metodo de profilaxis y tratamiento y agentes utiles para los mismos AR024151A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AUPQ0652A AUPQ065299A0 (en) 1999-05-28 1999-05-28 A method of prophylaxis and treatment and agents useful for same

Publications (1)

Publication Number Publication Date
AR024151A1 true AR024151A1 (es) 2002-09-04

Family

ID=3814852

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP000102652A AR024151A1 (es) 1999-05-28 2000-05-29 Un metodo de profilaxis y tratamiento y agentes utiles para los mismos

Country Status (8)

Country Link
EP (1) EP1189630B1 (es)
AR (1) AR024151A1 (es)
AT (1) ATE459372T1 (es)
AU (1) AUPQ065299A0 (es)
CA (1) CA2375269C (es)
DE (1) DE60043936D1 (es)
NZ (1) NZ515853A (es)
WO (1) WO2000072875A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2533794A4 (en) * 2010-02-12 2014-04-23 Univ Sydney PROTEINDOMAINS AND USES THEREOF
SG11202003147XA (en) 2017-10-12 2020-05-28 Vaxcyte Inc Periodontitis vaccine and related compositions and method of use

Also Published As

Publication number Publication date
EP1189630B1 (en) 2010-03-03
WO2000072875A1 (en) 2000-12-07
CA2375269A1 (en) 2000-12-07
CA2375269C (en) 2012-12-18
EP1189630A1 (en) 2002-03-27
DE60043936D1 (de) 2010-04-15
ATE459372T1 (de) 2010-03-15
EP1189630A4 (en) 2004-08-18
AUPQ065299A0 (en) 1999-06-24
NZ515853A (en) 2005-05-27

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