AR023625A1 - Compuestos no estequiometricos formados entre primicina y ciclodextrina - Google Patents
Compuestos no estequiometricos formados entre primicina y ciclodextrinaInfo
- Publication number
- AR023625A1 AR023625A1 ARP970101304A ARP970101304A AR023625A1 AR 023625 A1 AR023625 A1 AR 023625A1 AR P970101304 A ARP970101304 A AR P970101304A AR P970101304 A ARP970101304 A AR P970101304A AR 023625 A1 AR023625 A1 AR 023625A1
- Authority
- AR
- Argentina
- Prior art keywords
- primicin
- primicine
- estequiometric
- cyclodextrine
- compounds formed
- Prior art date
Links
- HFHDHCJBZVLPGP-UHFFFAOYSA-N schardinger α-dextrin Chemical compound O1C(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(O)C2O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC2C(O)C(O)C1OC2CO HFHDHCJBZVLPGP-UHFFFAOYSA-N 0.000 title abstract 3
- 229920000858 Cyclodextrin Polymers 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 title abstract 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- 230000003115 biocidal effect Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
- A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nanotechnology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Medical Informatics (AREA)
- Crystallography & Structural Chemistry (AREA)
- Biophysics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
El campo de accion del presente lo constituyen los preparados farmacéuticos antibioticos, en particular de aplicacion local, basados en la primicina. Laprimicina tiene el inconveniente de ser poco soluble, tanto en agua como en alcohol. Paraaumentar la solubilidad de la primicina, el presente propone nuevoscompuestos no estequiométricos, formados entre primicina o sus componentes, y una ciclodextrina o un derivado de ciclodextrina o mezcla de ellos, en unarelacion molar comprendidaentre 1:0,3 y 1:4,0.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU9600847A HUP9600847A3 (en) | 1996-04-02 | 1996-04-02 | Nonstochiometric compds. of primycins with ciclodextrin derivatives, pharmaceutical compns. contg. the said compds. and process for preparing them |
Publications (1)
Publication Number | Publication Date |
---|---|
AR023625A1 true AR023625A1 (es) | 2002-09-04 |
Family
ID=89993853
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP970101304A AR023625A1 (es) | 1996-04-02 | 1997-04-02 | Compuestos no estequiometricos formados entre primicina y ciclodextrina |
Country Status (4)
Country | Link |
---|---|
AR (1) | AR023625A1 (es) |
AU (1) | AU2173297A (es) |
HU (1) | HUP9600847A3 (es) |
WO (1) | WO1997036935A1 (es) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU1918700A (en) * | 1998-11-23 | 2000-06-13 | Procter & Gamble Company, The | Skin deodorizing and sanitizing compositions |
PE20020300A1 (es) | 2000-08-22 | 2002-05-10 | Pharmacia Corp | Composicion de solucion de un farmaco antibiotico a base de oxazolidinona con mejoramiento de la carga de farmaco |
US20060257488A1 (en) * | 2005-05-10 | 2006-11-16 | Cytophil, Inc. | Injectable hydrogels and methods of making and using same |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HU196822B (en) * | 1984-07-03 | 1989-01-30 | Chinoin Gyogyszer Es Vegyeszet | Process for producing primicin salts |
-
1996
- 1996-04-02 HU HU9600847A patent/HUP9600847A3/hu unknown
-
1997
- 1997-03-28 WO PCT/HU1997/000010 patent/WO1997036935A1/en active Application Filing
- 1997-03-28 AU AU21732/97A patent/AU2173297A/en not_active Abandoned
- 1997-04-02 AR ARP970101304A patent/AR023625A1/es unknown
Also Published As
Publication number | Publication date |
---|---|
HU9600847D0 (en) | 1996-05-28 |
HUP9600847A2 (hu) | 1998-01-28 |
AU2173297A (en) | 1997-10-22 |
WO1997036935A1 (en) | 1997-10-09 |
HUP9600847A3 (en) | 1999-08-30 |
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Legal Events
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