AR020919A1 - Procedimiento y compuestos intermediarios para preparar derivados de nicotinamidas - Google Patents

Procedimiento y compuestos intermediarios para preparar derivados de nicotinamidas

Info

Publication number
AR020919A1
AR020919A1 ARP990105300A ARP990105300A AR020919A1 AR 020919 A1 AR020919 A1 AR 020919A1 AR P990105300 A ARP990105300 A AR P990105300A AR P990105300 A ARP990105300 A AR P990105300A AR 020919 A1 AR020919 A1 AR 020919A1
Authority
AR
Argentina
Prior art keywords
formula
compound
reacting
nicotinamid
derivatives
Prior art date
Application number
ARP990105300A
Other languages
English (en)
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of AR020919A1 publication Critical patent/AR020919A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/08Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions not involving the formation of amino groups, hydroxy groups or etherified or esterified hydroxy groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/02Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C215/22Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated
    • C07C215/28Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

Un procedimiento para preparar un compuesto de la formula (5) que comprende hacer reaccionar un compuesto de la formula (4) con una base de carbonato enel seno de un disolvente a base de un alcohol. El compuesto de la formula (4) se prepara haciendoreaccionar un compuesto de la formula (3) con un reactivode metil-Grignard en el seno de un disolvente inerte. El compuesto de la formula (3) se prepara haciendo reaccionar un compuesto de formula (2) conanhídrido acético y una base amínica en el seno de un disolvente clorado. El compuesto de la formula (2) se prepara haciendo reaccionar un compuesto deformula (1) con un alcohol en un medio ácido para formar un grupo de éster. El presente incluye también nuevos compuestos de la formula (3) en laque R esalquilo C1-6 y de la formula (5).
ARP990105300A 1998-10-21 1999-10-20 Procedimiento y compuestos intermediarios para preparar derivados de nicotinamidas AR020919A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10512098P 1998-10-21 1998-10-21

Publications (1)

Publication Number Publication Date
AR020919A1 true AR020919A1 (es) 2002-06-05

Family

ID=22304138

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP990105300A AR020919A1 (es) 1998-10-21 1999-10-20 Procedimiento y compuestos intermediarios para preparar derivados de nicotinamidas

Country Status (10)

Country Link
JP (1) JP2000128835A (es)
KR (1) KR20000029190A (es)
AR (1) AR020919A1 (es)
AU (1) AU5595399A (es)
BR (1) BR9904696A (es)
CA (1) CA2286646A1 (es)
HU (1) HU9903736D0 (es)
IL (1) IL132405A0 (es)
PL (1) PL336111A1 (es)
ZA (1) ZA996624B (es)

Also Published As

Publication number Publication date
BR9904696A (pt) 2000-08-08
ZA996624B (en) 2001-04-20
HU9903736D0 (en) 1999-12-28
KR20000029190A (ko) 2000-05-25
JP2000128835A (ja) 2000-05-09
PL336111A1 (en) 2000-04-25
AU5595399A (en) 2000-05-04
CA2286646A1 (en) 2000-04-21
IL132405A0 (en) 2001-03-19

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