AR020919A1 - PROCEDURE AND INTERMEDIATE COMPOUNDS TO PREPARE NICOTINAMID DERIVATIVES - Google Patents
PROCEDURE AND INTERMEDIATE COMPOUNDS TO PREPARE NICOTINAMID DERIVATIVESInfo
- Publication number
- AR020919A1 AR020919A1 ARP990105300A ARP990105300A AR020919A1 AR 020919 A1 AR020919 A1 AR 020919A1 AR P990105300 A ARP990105300 A AR P990105300A AR P990105300 A ARP990105300 A AR P990105300A AR 020919 A1 AR020919 A1 AR 020919A1
- Authority
- AR
- Argentina
- Prior art keywords
- formula
- compound
- reacting
- nicotinamid
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/08—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions not involving the formation of amino groups, hydroxy groups or etherified or esterified hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C215/22—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated
- C07C215/28—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pyridine Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Un procedimiento para preparar un compuesto de la formula (5) que comprende hacer reaccionar un compuesto de la formula (4) con una base de carbonato enel seno de un disolvente a base de un alcohol. El compuesto de la formula (4) se prepara haciendoreaccionar un compuesto de la formula (3) con un reactivode metil-Grignard en el seno de un disolvente inerte. El compuesto de la formula (3) se prepara haciendo reaccionar un compuesto de formula (2) conanhídrido acético y una base amínica en el seno de un disolvente clorado. El compuesto de la formula (2) se prepara haciendo reaccionar un compuesto deformula (1) con un alcohol en un medio ácido para formar un grupo de éster. El presente incluye también nuevos compuestos de la formula (3) en laque R esalquilo C1-6 y de la formula (5).A process for preparing a compound of the formula (5) which comprises reacting a compound of the formula (4) with a carbonate base in a solvent based on an alcohol. The compound of the formula (4) is prepared by reacting a compound of the formula (3) with a methyl-Grignard reagent in an inert solvent. The compound of the formula (3) is prepared by reacting a compound of the formula (2) with acetic anhydride and an amine base within a chlorinated solvent. The compound of the formula (2) is prepared by reacting a deformula compound (1) with an alcohol in an acidic medium to form an ester group. The present also includes new compounds of the formula (3) in which R is C1-6 alkyl and of the formula (5).
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10512098P | 1998-10-21 | 1998-10-21 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR020919A1 true AR020919A1 (en) | 2002-06-05 |
Family
ID=22304138
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP990105300A AR020919A1 (en) | 1998-10-21 | 1999-10-20 | PROCEDURE AND INTERMEDIATE COMPOUNDS TO PREPARE NICOTINAMID DERIVATIVES |
Country Status (10)
Country | Link |
---|---|
JP (1) | JP2000128835A (en) |
KR (1) | KR20000029190A (en) |
AR (1) | AR020919A1 (en) |
AU (1) | AU5595399A (en) |
BR (1) | BR9904696A (en) |
CA (1) | CA2286646A1 (en) |
HU (1) | HU9903736D0 (en) |
IL (1) | IL132405A0 (en) |
PL (1) | PL336111A1 (en) |
ZA (1) | ZA996624B (en) |
-
1999
- 1999-10-14 IL IL13240599A patent/IL132405A0/en unknown
- 1999-10-19 AU AU55953/99A patent/AU5595399A/en not_active Abandoned
- 1999-10-19 CA CA002286646A patent/CA2286646A1/en not_active Abandoned
- 1999-10-20 HU HU9903736A patent/HU9903736D0/en unknown
- 1999-10-20 KR KR1019990045464A patent/KR20000029190A/en not_active Application Discontinuation
- 1999-10-20 ZA ZA9906624A patent/ZA996624B/en unknown
- 1999-10-20 JP JP11298121A patent/JP2000128835A/en active Pending
- 1999-10-20 BR BR9904696-2A patent/BR9904696A/en not_active Application Discontinuation
- 1999-10-20 AR ARP990105300A patent/AR020919A1/en unknown
- 1999-10-20 PL PL99336111A patent/PL336111A1/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
ZA996624B (en) | 2001-04-20 |
HU9903736D0 (en) | 1999-12-28 |
CA2286646A1 (en) | 2000-04-21 |
JP2000128835A (en) | 2000-05-09 |
PL336111A1 (en) | 2000-04-25 |
AU5595399A (en) | 2000-05-04 |
BR9904696A (en) | 2000-08-08 |
KR20000029190A (en) | 2000-05-25 |
IL132405A0 (en) | 2001-03-19 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
FI940788A0 (en) | Alcohol or aldehyde derivatives and their use | |
KR870001142A (en) | Preparation of Phenyl Ether | |
EE200300024A (en) | Process for the preparation of 2- (6-substituted-1,3-dioxan-4-yl) -acetic acid derivative, starting compound and end products | |
DE69721134D1 (en) | Process for the preparation of 4- (2- (2-pyridyl) ethoxy) benzaldehyde derivatives | |
ATE239619T1 (en) | RECORDING MATERIAL AND IMAGE PRINTING PROCESS USING SUCH MATERIAL | |
DK1515962T3 (en) | Process for preparing dioxane acetic acid esters | |
EP1477488A4 (en) | Novel optically active compounds, method for kinetic optical resolution of carboxylic acid derivatives and catalysts therefor | |
EP1288275A3 (en) | Electrochromic solution containing a hydrazone compound and device manufactured with same | |
DE60036076D1 (en) | PROCESS FOR PREPARING A PIPERAZINE DERIVATIVE | |
AR020919A1 (en) | PROCEDURE AND INTERMEDIATE COMPOUNDS TO PREPARE NICOTINAMID DERIVATIVES | |
DE69915413D1 (en) | Process for the preparation of 4-phenyl-1,2,3,6-tetrahydropyridine derivatives and the intermediates used therefor | |
IL108829A0 (en) | Enzymatic resolution of alkyl 2-piperidinecarboxylates and use of the compounds obtained as synthesis intermediates | |
AR018675A1 (en) | DERIVATIVES OF 3- (2-OXO- [1,3¿I¿] BIPIRROLIDINIL-3-ILIDENOMETIL) -CEFEM, A PHARMACEUTICAL COMPOSITION AND THE USE OF THEM FOR THE MANUFACTURE OF A MEDICINAL PRODUCT. | |
BR9810685B1 (en) | process for the preparation of a compound. | |
AU8143487A (en) | New derivatives of 2,2-dimethyl cyclopropane carboxylic acid having a saturated halogenated chain in position 3, the process and the intermediates for their preparation, their use as pesticides and the compositions containing them | |
BR0210512A (en) | (R) - (-) - 2-Hydroxy-2- (2-chlorophenyl) acetic acid decomposition process | |
FI961680A0 (en) | Process for the preparation of asymmetrically substituted triazines | |
KR900018059A (en) | Method for preparing 3,3-diphenyl acrylic acid amide | |
KR930007880A (en) | Bis (phenyl) ethane derivatives | |
DE50202775D1 (en) | Process for the preparation of beta-ketonitriles | |
DE59010041D1 (en) | Manufacture of dioxolane derivatives | |
PT798297E (en) | Process for the production of 2-ALCOXY-6- (TRIFLUOROMETHYL) -PYRIDIN-4-OL " | |
AU3051200A (en) | Method for preparing azoiminoethers and azocarboxylic acid esters and novel azocarboxylic acid mixed esters | |
KR860001811A (en) | Method for preparing tetracyclic spiro-hydantoin derivative | |
GB2243371B (en) | Ink,ink-jet recording method,and instrument employing the ink |