AR015825A1 - FERMENTATIVE PRODUCTION OF CLAVULANIC ACID UNDER CONTROLLED PHOSPHATE CONDITIONS - Google Patents

FERMENTATIVE PRODUCTION OF CLAVULANIC ACID UNDER CONTROLLED PHOSPHATE CONDITIONS

Info

Publication number
AR015825A1
AR015825A1 ARP980102429A ARP980102429A AR015825A1 AR 015825 A1 AR015825 A1 AR 015825A1 AR P980102429 A ARP980102429 A AR P980102429A AR P980102429 A ARP980102429 A AR P980102429A AR 015825 A1 AR015825 A1 AR 015825A1
Authority
AR
Argentina
Prior art keywords
clavulanic acid
acid under
under controlled
fermentative production
phosphate conditions
Prior art date
Application number
ARP980102429A
Other languages
Spanish (es)
Original Assignee
Gist Brocades Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gist Brocades Bv filed Critical Gist Brocades Bv
Publication of AR015825A1 publication Critical patent/AR015825A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/188—Heterocyclic compound containing in the condensed system at least one hetero ring having nitrogen atoms and oxygen atoms as the only ring heteroatoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Se provee un proceso corregido para la preparacion fermentativa de ácido clavulánico en el cual se controla el nivel de fosfato libre en el medio defermentacion al comienzo de la fermentacion y/o durante la fermentacion.A corrected process is provided for the fermentative preparation of clavulanic acid in which the level of free phosphate in the defermentation medium is controlled at the beginning of the fermentation and / or during the fermentation.

ARP980102429A 1997-05-28 1998-05-26 FERMENTATIVE PRODUCTION OF CLAVULANIC ACID UNDER CONTROLLED PHOSPHATE CONDITIONS AR015825A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP97201561 1997-05-28

Publications (1)

Publication Number Publication Date
AR015825A1 true AR015825A1 (en) 2001-05-30

Family

ID=8228356

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP980102429A AR015825A1 (en) 1997-05-28 1998-05-26 FERMENTATIVE PRODUCTION OF CLAVULANIC ACID UNDER CONTROLLED PHOSPHATE CONDITIONS

Country Status (7)

Country Link
EP (1) EP0985048A1 (en)
AR (1) AR015825A1 (en)
AU (1) AU7655198A (en)
CO (1) CO4790117A1 (en)
PE (1) PE74999A1 (en)
WO (1) WO1998054352A1 (en)
ZA (1) ZA984566B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6440708B1 (en) 1998-09-29 2002-08-27 Dsm N.V. Fermentation of clavulanic acid at a controlled level of ammonia

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE41109B1 (en) * 1974-04-20 1979-10-24 Beecham Group Ltd Novel -lactam antibiotic from streptomyces clavuligerus
US4110165A (en) * 1974-04-20 1978-08-29 Beecham Group Limited Process for the production of clavulanic acid
GB1563103A (en) * 1975-10-13 1980-03-19 Beecham Group Ltd Process for the preparation of clavulanic acid
GB1571888A (en) * 1977-02-04 1980-07-23 Glaxo Lab Ltd Clavulanic acid production
MX7417E (en) * 1984-10-27 1988-10-14 Antibioticos Sa METHOD FOR THE PREPARATION OF CLAVULANIC ACID AND ITS DERIVATIVES
GB9424950D0 (en) * 1994-12-10 1995-02-08 Smithkline Beecham Plc Novel process
SI9500134B (en) * 1995-04-20 2004-04-30 Lek, Preparation procedure of pure alkali salts of clavulanic acid
ES2101658B1 (en) * 1995-11-23 1998-03-01 Antibioticos Sa NEW PROCEDURE FOR THE PRODUCTION OF CLAVULANIC ACID AND ITS SALTS.
SI9600120A (en) * 1996-04-12 1997-12-31 Lek Tovarna Farmacevtskih New and improved fermentative procedure for the production of clavulanic acid and its salts

Also Published As

Publication number Publication date
AU7655198A (en) 1998-12-30
ZA984566B (en) 1999-02-19
WO1998054352A1 (en) 1998-12-03
CO4790117A1 (en) 1999-05-31
PE74999A1 (en) 1999-08-12
EP0985048A1 (en) 2000-03-15

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