EP0670370A3 - Method of producing L-glutamic acid by fermentation. - Google Patents

Method of producing L-glutamic acid by fermentation. Download PDF

Info

Publication number
EP0670370A3
EP0670370A3 EP95100259A EP95100259A EP0670370A3 EP 0670370 A3 EP0670370 A3 EP 0670370A3 EP 95100259 A EP95100259 A EP 95100259A EP 95100259 A EP95100259 A EP 95100259A EP 0670370 A3 EP0670370 A3 EP 0670370A3
Authority
EP
European Patent Office
Prior art keywords
fermentation
producing
glutamic acid
glutamic
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP95100259A
Other languages
German (de)
French (fr)
Other versions
EP0670370B1 (en
EP0670370A2 (en
Inventor
Eiji Ono
Nobuharu Tsujimoto
Kazuhiko Matsui
Osamu Kurahashi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ajinomoto Co Inc
Original Assignee
Ajinomoto Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ajinomoto Co Inc filed Critical Ajinomoto Co Inc
Publication of EP0670370A2 publication Critical patent/EP0670370A2/en
Publication of EP0670370A3 publication Critical patent/EP0670370A3/en
Application granted granted Critical
Publication of EP0670370B1 publication Critical patent/EP0670370B1/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/14—Glutamic acid; Glutamine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
EP95100259A 1994-01-10 1995-01-10 Method of producing L-glutamic acid by fermentation Expired - Lifetime EP0670370B1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP82594 1994-01-10
JP825/94 1994-01-10
JP00082594A JP3880636B2 (en) 1994-01-10 1994-01-10 Method for producing L-glutamic acid by fermentation

Publications (3)

Publication Number Publication Date
EP0670370A2 EP0670370A2 (en) 1995-09-06
EP0670370A3 true EP0670370A3 (en) 1997-05-28
EP0670370B1 EP0670370B1 (en) 2003-04-09

Family

ID=11484433

Family Applications (1)

Application Number Title Priority Date Filing Date
EP95100259A Expired - Lifetime EP0670370B1 (en) 1994-01-10 1995-01-10 Method of producing L-glutamic acid by fermentation

Country Status (9)

Country Link
US (1) US5573945A (en)
EP (1) EP0670370B1 (en)
JP (1) JP3880636B2 (en)
CN (1) CN1071794C (en)
BR (1) BR9500052A (en)
DE (1) DE69530242T2 (en)
ES (1) ES2194030T3 (en)
MY (1) MY112424A (en)
PE (1) PE42395A1 (en)

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US6969782B2 (en) 1993-10-06 2005-11-29 Ajinomoto Co., Inc. Method of producing transgenic plants having improved amino acid composition
DE19681532T1 (en) * 1995-08-23 1998-12-03 Ajinomoto Kk Process for the production of L-glutamic acid by fermentation
JP4032441B2 (en) * 1995-08-30 2008-01-16 味の素株式会社 Method for producing L-amino acid
JPH09285294A (en) * 1996-04-23 1997-11-04 Ajinomoto Co Inc Production of l-glutamic acid by fermentation
TW460622B (en) 1998-02-03 2001-10-21 Atotech Deutschland Gmbh Solution and process to pretreat copper surfaces
AU756507B2 (en) 1998-03-18 2003-01-16 Ajinomoto Co., Inc. L-glutamic acid-producing bacterium and method for producing L-glutamic acid
AU746542B2 (en) 1998-03-18 2002-05-02 Ajinomoto Co., Inc. L-glutamic acid-producing bacterium and method for producing L-glutamic acid
FR2780416B1 (en) * 1998-06-10 2002-12-20 Rhone Poulenc Nutrition Animal INDUSTRIAL PROCESS FOR PRODUCING HETEROLOGOUS PROTEINS IN E. COLI AND STRAINS USEFUL FOR THE PROCESS
AU761990B2 (en) * 1998-10-19 2003-06-12 Ajinomoto Co., Inc. L-glutamic acid producing bacterium and process for producing L-glutamic acid
CN1067434C (en) * 1998-12-28 2001-06-20 山东大学 Glutamine fermentation production process
EP1026236A1 (en) * 1999-02-04 2000-08-09 Dsm N.V. Auxotrophic strains for secondary metabolite biosynthesis
DE19904794A1 (en) * 1999-02-05 2000-08-10 Biotechnolog Forschung Gmbh Methods for improving the primary metabolism of mammalian cell lines
JP4427878B2 (en) * 1999-08-20 2010-03-10 味の素株式会社 Method for producing L-glutamic acid by fermentation method with precipitation
JP4362959B2 (en) * 2000-08-24 2009-11-11 味の素株式会社 Method for producing basic amino acid
JP4292724B2 (en) 2001-02-20 2009-07-08 味の素株式会社 Organic nitrogen-containing composition and fertilizer containing the same
JP4599725B2 (en) * 2001-02-20 2010-12-15 味の素株式会社 Method for producing L-glutamic acid
JP2002238592A (en) 2001-02-20 2002-08-27 Ajinomoto Co Inc Method for producing l-glutamic acid
JP4599726B2 (en) 2001-02-20 2010-12-15 味の素株式会社 Method for producing L-glutamic acid
DK1407027T3 (en) * 2001-07-18 2009-09-28 Evonik Degussa Gmbh Process for Preparation of L-Threonine Using Strains of the Enterobacteriaceae Family Containing Enhanced Suc and SucD Genes
EP1604023A2 (en) * 2003-03-12 2005-12-14 Ajinomoto Co., Inc. Optimization of bacterial sucab expression by promoter mutagenesis for efficient l-glutamic acid production
EP1624069A4 (en) 2003-05-07 2011-06-29 Ajinomoto Kk Process for producing l-glutamic acid
JP2005021154A (en) * 2003-06-11 2005-01-27 Ajinomoto Co Inc Method for producing l-amino acid
JP2005065641A (en) * 2003-08-27 2005-03-17 Mitsubishi Chemicals Corp Method for producing non-amino organic acid
US7344874B2 (en) 2004-03-04 2008-03-18 Ajinomoto Co., Inc. L-glutamic acid-producing microorganism and a method for producing L-glutamic acid
US8003367B2 (en) * 2004-03-16 2011-08-23 Ajinomoto Co., Inc. Method for producing L-amino acids by fermentation using bacteria having enhanced expression of xylose utilization genes
DE102005048818A1 (en) 2005-10-10 2007-04-12 Degussa Ag Microbiological production of 3-hydroxypropionic acid
JP2009118740A (en) 2006-03-03 2009-06-04 Ajinomoto Co Inc Method for producing l-amino acid
EP2351830B1 (en) 2006-03-23 2014-04-23 Ajinomoto Co., Inc. A method for producing an L-amino acid using bacterium of the Enterobacteriaceae family with attenuated expression of a gene coding for small RNA
JP2009165355A (en) 2006-04-28 2009-07-30 Ajinomoto Co Inc L-amino acid-producing microorganism and method for producing l-amino acid
RU2006143864A (en) 2006-12-12 2008-06-20 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) (RU) METHOD FOR PRODUCING L-AMINO ACIDS USING THE BACTERIA OF THE ENTEROBACTERIACEAE FAMILY IN WHICH THE EXPRESSION OF GENES cynT, cynS, cynX, OR cynR, OR THEIR COMBINATION IS DECREASED
JP5540504B2 (en) 2007-01-22 2014-07-02 味の素株式会社 Microorganism producing L-amino acid and method for producing L-amino acid
JP2010110217A (en) 2007-02-22 2010-05-20 Ajinomoto Co Inc L-amino acid-producing microorganism and method for producing l-amino acid
JP2010130899A (en) 2007-03-14 2010-06-17 Ajinomoto Co Inc Microorganism producing l-glutamic acid-based amino acid, and method for producing amino acid
CN101688176B (en) 2007-04-17 2013-11-06 味之素株式会社 Method for production of acidic substance having carboxyl group
RU2007147436A (en) * 2007-12-21 2009-06-27 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) (RU) BACTERIA-PRODUCER (2S, 3R, 4S) -4-HYDROXY-L-ISOLEUCIN AND METHOD FOR PRODUCTION (2S, 3R, 4S) -4-HYDROXY-L-ISOLEUCIN
KR20100120663A (en) 2008-01-23 2010-11-16 아지노모토 가부시키가이샤 Method of producing l-amino acid
RU2008105793A (en) 2008-02-19 2009-08-27 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) (RU) METHOD FOR DESIGNING OPERONS CONTAINING TRANSLATION-CONJUGATED GENES, BACTERIA CONTAINING SUCH OPERON, METHOD FOR PRODUCING USEFUL METABOLITIS AND METHOD FOR EXPRESS MONITORING
JP5488467B2 (en) 2008-09-05 2014-05-14 味の素株式会社 L-amino acid producing bacterium and method for producing L-amino acid
KR101627095B1 (en) 2008-09-08 2016-06-03 아지노모토 가부시키가이샤 Microorganism capable of producing L-amino acid, and method for producing L-amino acid
WO2010084995A2 (en) 2009-01-23 2010-07-29 Ajinomoto Co.,Inc. A method for producing an l-amino acid
CN102471790B (en) 2009-07-29 2014-10-29 味之素株式会社 Method for producing l-amino acid
RU2460793C2 (en) 2010-01-15 2012-09-10 Закрытое акционерное общество "Научно-исследовательский институт "Аджиномото-Генетика" (ЗАО АГРИ) Method for producing l-amino acids with use of bacteria of enterobacteriaceae family
JP2013074795A (en) 2010-02-08 2013-04-25 Ajinomoto Co Inc MUTANT rpsA GENE AND METHOD FOR PRODUCING L-AMINO ACID
RU2471868C2 (en) 2010-02-18 2013-01-10 Закрытое акционерное общество "Научно-исследовательский институт "Аджиномото-Генетика" (ЗАО АГРИ) Mutant adenylate cyclase, dna coding it, bacteria of enterobacteriaceae family containing said dan and method for preparing l-amino acids
DE102010029973A1 (en) 2010-06-11 2011-12-15 Evonik Degussa Gmbh Microbiological production of C4 bodies from sucrose and carbon dioxide
RU2482188C2 (en) 2010-07-21 2013-05-20 Закрытое акционерное общество "Научно-исследовательский институт "Аджиномото-Генетика" (ЗАО АГРИ) METHOD FOR PREPARING L-ARGININE WITH USE OF BACTERIA OF GENUS Escherichia WHEREIN astCADBE OPERON IS INACTIVATED
RU2501858C2 (en) 2010-07-21 2013-12-20 Закрытое акционерное общество "Научно-исследовательский институт "Аджиномото-Генетика" (ЗАО АГРИ) METHOD FOR OBTAINING L-AMINOACID USING BACTERIUM OF Enterobacteriaceae FAMILY
JP2014036576A (en) 2010-12-10 2014-02-27 Ajinomoto Co Inc Method for producing l-amino acids
RU2011134436A (en) 2011-08-18 2013-10-27 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО "АГРИ") METHOD FOR PRODUCING L-AMINO ACID USING THE ENTEROBACTERIACEAE FAMILY POSSESSING AN INCREASED EXPRESSION OF GENES OF THE CASCADE OF THE FORMATION OF FLAGELLS AND CELL MOBILITY
RU2013118637A (en) 2013-04-23 2014-10-27 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО "АГРИ") METHOD FOR PRODUCING L-AMINO ACIDS USING THE BACTERIA OF THE ENTEROBACTERIACEAE FAMILY IN WHICH THE yjjK GENE IS ADJUSTABLE
JP2016165225A (en) 2013-07-09 2016-09-15 味の素株式会社 Method for producing useful substance
RU2013140115A (en) 2013-08-30 2015-03-10 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО "АГРИ") METHOD FOR PRODUCING L-AMINO ACIDS USING THE BACTERIA OF THE Enterobacteriaceae FAMILY IN WHICH THE EXPRESSION OF THE znuACB GENERAL CLUSTER IS DISORDERED
JP2016192903A (en) 2013-09-17 2016-11-17 味の素株式会社 Method for manufacturing l-amino acid from biomass derived from seaweed
RU2013144250A (en) 2013-10-02 2015-04-10 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО "АГРИ") METHOD FOR PRODUCING L-AMINO ACIDS USING THE BACTERIA OF THE Enterobacteriaceae FAMILY IN WHICH THE EXPRESSION OF A GENE CODING A PHOSPHATE TRANSPORTER IS DECREASED
JP6459962B2 (en) 2013-10-21 2019-01-30 味の素株式会社 Method for producing L-amino acid
US10006575B2 (en) 2013-12-11 2018-06-26 Nibco Inc. Modular push-to-connect assembly
RU2014105547A (en) 2014-02-14 2015-08-20 Адзиномото Ко., Инк. METHOD FOR PRODUCING L-AMINO ACIDS USING THE ENTEROBACTERIACEAE FAMILY HAVING A SUPER EXPRESSED GENE yajL
RU2015120052A (en) 2015-05-28 2016-12-20 Аджиномото Ко., Инк. A method for producing an L-amino acid using a bacterium of the Enterobacteriaceae family in which gshA gene expression is weakened
BR112018017227A2 (en) 2016-02-25 2019-02-05 Ajinomoto Kk method to produce an l-amino acid
JP7066977B2 (en) 2017-04-03 2022-05-16 味の素株式会社 Manufacturing method of L-amino acid
EP3861109A1 (en) 2018-10-05 2021-08-11 Ajinomoto Co., Inc. Method for producing target substance by bacterial fermentation
JP2022521544A (en) 2019-02-22 2022-04-08 味の素株式会社 Method for producing L-amino acid using a bacterium belonging to the family Enterobacteriaceae that overexpresses the ydiJ gene
JP2022526181A (en) 2019-04-05 2022-05-23 味の素株式会社 Method for producing L-amino acid
JP2022550084A (en) 2019-09-25 2022-11-30 味の素株式会社 Method for producing L-amino acid by bacterial fermentation
US20240117393A1 (en) 2022-09-30 2024-04-11 Ajinomoto Co., Inc. Method for producing l-amino acid

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0143195A1 (en) * 1983-08-29 1985-06-05 Ajinomoto Co., Inc. Recombinant DNA having a phosphoenol pyruvate carboxylase gene inserted therein, bacteria carrying said recombinant DNA and a process for producing amino acids using said bacteria
FR2575492A1 (en) * 1984-12-27 1986-07-04 Asahi Chemical Ind DNA fragment containing a gene encoding glutamate dehydrogenase, recombinant DNA containing it, and a recombinant microorganism containing the recombinant DNA
FR2680178A1 (en) * 1991-08-07 1993-02-12 Ajinomoto Kk Process for producing L-glutamic acid by fermentation

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JPS568693A (en) * 1979-06-29 1981-01-29 Ajinomoto Co Inc Preparation of l-glutamic acid
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JPS5820194A (en) * 1981-07-29 1983-02-05 Ajinomoto Co Inc Preparation of l-glutamic acid by fermentation method
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Patent Citations (3)

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EP0143195A1 (en) * 1983-08-29 1985-06-05 Ajinomoto Co., Inc. Recombinant DNA having a phosphoenol pyruvate carboxylase gene inserted therein, bacteria carrying said recombinant DNA and a process for producing amino acids using said bacteria
FR2575492A1 (en) * 1984-12-27 1986-07-04 Asahi Chemical Ind DNA fragment containing a gene encoding glutamate dehydrogenase, recombinant DNA containing it, and a recombinant microorganism containing the recombinant DNA
FR2680178A1 (en) * 1991-08-07 1993-02-12 Ajinomoto Kk Process for producing L-glutamic acid by fermentation

Also Published As

Publication number Publication date
JPH07203980A (en) 1995-08-08
MY112424A (en) 2001-06-30
PE42395A1 (en) 1996-01-04
EP0670370B1 (en) 2003-04-09
ES2194030T3 (en) 2003-11-16
EP0670370A2 (en) 1995-09-06
JP3880636B2 (en) 2007-02-14
DE69530242D1 (en) 2003-05-15
US5573945A (en) 1996-11-12
CN1128295A (en) 1996-08-07
BR9500052A (en) 1995-10-03
CN1071794C (en) 2001-09-26
DE69530242T2 (en) 2004-03-11

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