AR014730A1 - Fragmento aislado de acidos nucleicos que codifica una proteina de factor 1 asociadas con xiap, gen quimerico, celula huesped transformada, polipeptdo,metodo para alterar el nivel de expresion de dicha enzima, metodos para obtener dicho fragmento, productos obtenidos por dichos metodos - Google Patents

Fragmento aislado de acidos nucleicos que codifica una proteina de factor 1 asociadas con xiap, gen quimerico, celula huesped transformada, polipeptdo,metodo para alterar el nivel de expresion de dicha enzima, metodos para obtener dicho fragmento, productos obtenidos por dichos metodos

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Publication number
AR014730A1
AR014730A1 ARP990101140A ARP990101140A AR014730A1 AR 014730 A1 AR014730 A1 AR 014730A1 AR P990101140 A ARP990101140 A AR P990101140A AR P990101140 A ARP990101140 A AR P990101140A AR 014730 A1 AR014730 A1 AR 014730A1
Authority
AR
Argentina
Prior art keywords
xiap
methods
protein
factor
altering
Prior art date
Application number
ARP990101140A
Other languages
English (en)
Original Assignee
Du Pont
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont filed Critical Du Pont
Publication of AR014730A1 publication Critical patent/AR014730A1/es

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C12N15/8262—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield involving plant development
    • C12N15/8263—Ablation; Apoptosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants

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  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Botany (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)

Abstract

Se describen fragmentos de ácidos nucleicos aislados que codifican proteínas que inhiben la apoptosis, más específicamente un fragmento aislado deácidos nucleicos que codifica una proteína de factor 1 asociada con XIAP, su complementario y el polipéptido que la codifica. Con respecto de la presentesolicitud, se relaciona con un gen quimérico que comprende un fragmento de ácidos nucleicos que codifica una proteína de factor 1 asociada con XIAP,ligado operativamente a secuencias reguladoras adecuadas, donde la expresion del gen quimérico da como resultado la produccion de niveles alterado (es decirincrementados o disminuídos) de la proteína codificada en una célula huésped transformada, que también se revela, con respecto a los niveles producidos enuna célula huésped no transformada. En realizaciones adicionales se refieren un método para alterar el nivel de expresion de una proteína de factor 1 asociadacon XIAP en una célula huésped transformada, un método para obtenerun fragmento de ácido nucleico que codifica toda una porcion sustancial de unasecuencia de aminoácidos codificadora de una proteína de factor 1 asociada con XIAP y los productos que se obtienen.
ARP990101140A 1998-03-16 1999-03-16 Fragmento aislado de acidos nucleicos que codifica una proteina de factor 1 asociadas con xiap, gen quimerico, celula huesped transformada, polipeptdo,metodo para alterar el nivel de expresion de dicha enzima, metodos para obtener dicho fragmento, productos obtenidos por dichos metodos AR014730A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US7814498P 1998-03-16 1998-03-16

Publications (1)

Publication Number Publication Date
AR014730A1 true AR014730A1 (es) 2001-03-28

Family

ID=22142199

Family Applications (2)

Application Number Title Priority Date Filing Date
ARP990101140A AR014730A1 (es) 1998-03-16 1999-03-16 Fragmento aislado de acidos nucleicos que codifica una proteina de factor 1 asociadas con xiap, gen quimerico, celula huesped transformada, polipeptdo,metodo para alterar el nivel de expresion de dicha enzima, metodos para obtener dicho fragmento, productos obtenidos por dichos metodos
ARP990101141A AR014731A1 (es) 1998-03-16 1999-03-16 Fragmento aislado de acidos nucleicos que codifica toda o una porcion sustancial de una proteina inhibidora de la apoptosis en plantas y semillas,gen quimerico, celula huesped transformada, polipeptido, metodo para alterar el nivel de expresion de dicha proteina en una celula huesped, metodos para

Family Applications After (1)

Application Number Title Priority Date Filing Date
ARP990101141A AR014731A1 (es) 1998-03-16 1999-03-16 Fragmento aislado de acidos nucleicos que codifica toda o una porcion sustancial de una proteina inhibidora de la apoptosis en plantas y semillas,gen quimerico, celula huesped transformada, polipeptido, metodo para alterar el nivel de expresion de dicha proteina en una celula huesped, metodos para

Country Status (6)

Country Link
US (1) US7071382B2 (es)
EP (2) EP1062355A1 (es)
AR (2) AR014730A1 (es)
AU (2) AU2995299A (es)
BR (1) BR9908025A (es)
WO (2) WO1999047688A1 (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6162965A (en) * 1997-06-02 2000-12-19 Novartis Ag Plant transformation methods
US8697950B2 (en) * 1999-11-10 2014-04-15 University Of Connecticut Vacuolar pyrophosphatases and uses in plants
US20020178464A1 (en) * 1999-11-10 2002-11-28 Whitehead Institute For Biomedical Research Proton transporters and uses in plants
US7534933B2 (en) * 2000-08-18 2009-05-19 University Of Connecticut Transgenic plants overexpressing a plant vacuolar H + -ATPase
AU2002248309A1 (en) * 2001-01-08 2002-07-16 The Burnham Institute Inhibitor of apoptosis proteins and nucleic acids and methods for making and using them
KR100583861B1 (ko) * 2002-10-01 2006-05-26 주식회사 핸슨바이오텍 항 에이파토시스 재조합 단백질 및 이를 포함하는 의약품,세포 배양용 배지 첨가물 및 건강 식품
KR100809663B1 (ko) * 2005-03-18 2008-03-05 주식회사 핸슨바이오텍 항 에이파토시스 재조합 단백질 및 이를 포함하는 의약품,세포 배양용 배지 첨가물 및 건강 식품
US20100049284A1 (en) * 2008-05-15 2010-02-25 The Catholic University Of America Use of heat to treat biological systems exposed to damaging radiation

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6162965A (en) * 1997-06-02 2000-12-19 Novartis Ag Plant transformation methods
CA2225187A1 (en) * 1997-07-14 1999-01-14 Universite D'ottawa/ University Of Ottawa Xaf genes and polypeptides: methods and reagents for modulating apoptosis

Also Published As

Publication number Publication date
AR014731A1 (es) 2001-03-28
EP1062355A1 (en) 2000-12-27
US20040111767A1 (en) 2004-06-10
EP1062353A2 (en) 2000-12-27
WO1999047689A3 (en) 1999-11-25
BR9908025A (pt) 2001-01-09
US7071382B2 (en) 2006-07-04
AU2995299A (en) 1999-10-11
WO1999047688A1 (en) 1999-09-23
WO1999047689A2 (en) 1999-09-23
AU2903099A (en) 1999-10-11

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