AR009532A1 - COMPUESTOS INTERMEDIARIOS DE SíNTESIS DE INHIBIDORES DE VIH-PROTEASA, MÉTODOS PARA SU PREPARACIoN Y UN PROCESO DE ELABORACIoN DE MESILATO DE NELFINAVIR - Google Patents
COMPUESTOS INTERMEDIARIOS DE SíNTESIS DE INHIBIDORES DE VIH-PROTEASA, MÉTODOS PARA SU PREPARACIoN Y UN PROCESO DE ELABORACIoN DE MESILATO DE NELFINAVIRInfo
- Publication number
- AR009532A1 AR009532A1 ARP970104038A ARP970104038A AR009532A1 AR 009532 A1 AR009532 A1 AR 009532A1 AR P970104038 A ARP970104038 A AR P970104038A AR P970104038 A ARP970104038 A AR P970104038A AR 009532 A1 AR009532 A1 AR 009532A1
- Authority
- AR
- Argentina
- Prior art keywords
- elaboration
- hiv
- preparation
- methods
- protease inhibitors
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/20—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D233/22—Radicals substituted by oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- Animal Behavior & Ethology (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Communicable Diseases (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Peptides Or Proteins (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/708,607 US5705647A (en) | 1996-09-05 | 1996-09-05 | Intermediates for making HIV-protease inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR009532A1 true AR009532A1 (es) | 2000-04-26 |
Family
ID=24846475
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP970104038A AR009532A1 (es) | 1996-09-05 | 1997-09-04 | COMPUESTOS INTERMEDIARIOS DE SíNTESIS DE INHIBIDORES DE VIH-PROTEASA, MÉTODOS PARA SU PREPARACIoN Y UN PROCESO DE ELABORACIoN DE MESILATO DE NELFINAVIR |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US5705647A (es) |
| EP (1) | EP0931071B1 (es) |
| JP (2) | JP2001501183A (es) |
| AR (1) | AR009532A1 (es) |
| AT (1) | ATE397591T1 (es) |
| AU (1) | AU4247097A (es) |
| CA (1) | CA2264725A1 (es) |
| CO (1) | CO4900044A1 (es) |
| DE (1) | DE69738751D1 (es) |
| ES (1) | ES2306461T3 (es) |
| ID (1) | ID17012A (es) |
| IN (1) | IN183739B (es) |
| MY (1) | MY132553A (es) |
| UY (1) | UY24697A1 (es) |
| WO (1) | WO1998009952A1 (es) |
| ZA (1) | ZA977868B (es) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5925759A (en) * | 1996-09-05 | 1999-07-20 | Agouron Pharmaceuticals, Inc. | Methods of making HIV-protease inhibitors and intermediates for making HIV-protease inhibitors |
| US5962725A (en) | 1996-09-05 | 1999-10-05 | Agouron Pharmaceuticals, Inc. | Intermediate compounds useful for making HIV protease inhibitors such as nelfinavir |
| US6001851A (en) * | 1997-03-13 | 1999-12-14 | Agouron Pharmaceuticals, Inc. | HIV protease inhibitors |
| US6130348A (en) * | 1997-04-10 | 2000-10-10 | Hoffmann-La Roche Inc. | Process for a phenylthiobutyl-isoquinoline and intermediates therefor |
| DE69812079T2 (de) * | 1997-04-10 | 2003-12-18 | Hoffmann La Roche | Verfahren zur herstellung eines buthylthuio-isochinolinderivates und zwischenprodukte dafür |
| US6084107A (en) * | 1997-09-05 | 2000-07-04 | Agouron Pharmaceuticals, Inc. | Intermediates for making HIV-protease inhibitors |
| WO1999048371A1 (en) * | 1998-03-27 | 1999-09-30 | The Regents Of The University Of California | Novel hiv integrase inhibitors and hiv therapy based on drug combinations including integrase inhibitors |
| US20050049242A1 (en) * | 2000-12-21 | 2005-03-03 | W. Edward Robinson | Novel HIV integrase inhibitors and HIV therapy based on drug combinations including integrase inhibitors |
| US6943001B2 (en) * | 2001-08-03 | 2005-09-13 | Diversa Corporation | Epoxide hydrolases, nucleic acids encoding them and methods for making and using them |
| WO2003012126A2 (en) * | 2001-08-03 | 2003-02-13 | Diversa Corporation | Epoxide hydrolases, nucleic acids encoding them and methods for making and using them |
| BRPI0410125A (pt) * | 2003-05-08 | 2006-05-09 | Pfizer | intermediários úteis para a sìntese de inibidores de protease de hiv, e métodos para os preparar |
| CN103098290B (zh) | 2010-10-22 | 2015-05-13 | 三井化学株式会社 | 环状硫酸酯化合物、含有其的非水电解液、及锂二次电池 |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5142056A (en) * | 1989-05-23 | 1992-08-25 | Abbott Laboratories | Retroviral protease inhibiting compounds |
| IL89900A0 (en) * | 1988-04-12 | 1989-12-15 | Merck & Co Inc | Hiv protease inhibitors useful for the treatment of aids and pharmaceutical compositions containing them |
| CA1340588C (en) * | 1988-06-13 | 1999-06-08 | Balraj Krishan Handa | Amino acid derivatives |
| IL91307A0 (en) * | 1988-08-24 | 1990-03-19 | Merck & Co Inc | Hiv protease inhibitors and pharmaceutical compositions for the treatment of aids containing them |
| EP0361341A3 (en) * | 1988-09-28 | 1991-07-03 | Miles Inc. | Therapeutics for aids based on inhibitors of hiv protease |
| US5063208A (en) * | 1989-07-26 | 1991-11-05 | Abbott Laboratories | Peptidyl aminodiol renin inhibitors |
| WO1991008221A1 (en) * | 1989-12-04 | 1991-06-13 | Wisconsin Alumni Research Foundation | Peptide inhibitors of hiv protease |
| GB8927913D0 (en) * | 1989-12-11 | 1990-02-14 | Hoffmann La Roche | Amino acid derivatives |
| GB8927915D0 (en) * | 1989-12-11 | 1990-02-14 | Hoffmann La Roche | Novel alcohols |
| CA2032259A1 (en) * | 1989-12-18 | 1991-06-19 | Wayne J. Thompson | Hiv protease inhibitors useful for the treatment of aids |
| CA2056911C (en) * | 1990-12-11 | 1998-09-22 | Yuuichi Nagano | Hiv protease inhibitors |
| IL100899A (en) * | 1991-02-08 | 1997-06-10 | Sankyo Co | Beta-amino-alpha- hydroxycarboxylic acid derivatives, processes for the preparation thereof and pharmaceutical compositions containing the same |
| US5235039A (en) * | 1991-06-10 | 1993-08-10 | Eli Lilly And Company | Substrates for hiv protease |
| CN1071930A (zh) * | 1991-07-10 | 1993-05-12 | 伊莱利利公司 | 用作治疗艾滋病的人免疫缺陷病毒蛋白酶的抑制剂 |
| DE4126482A1 (de) * | 1991-08-10 | 1993-02-11 | Bayer Ag | (alpha)-trifluormethyl-substituierte, gesaettigt-bicyclische amine und verfahren zu deren herstellung |
| US5516784A (en) * | 1991-08-13 | 1996-05-14 | Schering Corporation | Anti-HIV (AIDS) agents |
| EP0534511A1 (en) * | 1991-08-16 | 1993-03-31 | Merck & Co. Inc. | HIV protease inhibitors useful for the treatment of aids |
| US5256783A (en) * | 1991-09-18 | 1993-10-26 | Hoffmann-La Roche Inc. | Method for producing 2-isoquinoline compounds |
| WO1993008184A1 (en) * | 1991-10-23 | 1993-04-29 | Merck & Co., Inc. | Hiv protease inhibitors |
| ZA929869B (en) * | 1991-12-20 | 1994-06-20 | Syntex Inc | Hiv protease inhibitors |
| EP0560268B1 (en) * | 1992-03-13 | 1995-01-04 | Bio-Mega/Boehringer Ingelheim Research Inc. | Substituted pipecolinic acid derivatives as HIV protease inhibitors |
| WO1993023379A1 (en) * | 1992-05-21 | 1993-11-25 | Monsanto Company | Retroviral protease inhibitors |
| ATE172717T1 (de) * | 1992-08-25 | 1998-11-15 | Searle & Co | Hydroxyethylaminosulfonamide verwendbar als inhibitoren retroviraler proteasen |
| JP4091653B2 (ja) * | 1992-08-25 | 2008-05-28 | ジー．ディー．サール、リミテッド、ライアビリティ、カンパニー | レトロウイルスプロテアーゼ阻害剤として有用なｎ−（アルカノイルアミノ−２−ヒドロキシプロピル）スルホンアミド |
| IS2334B (is) * | 1992-09-08 | 2008-02-15 | Vertex Pharmaceuticals Inc., (A Massachusetts Corporation) | Aspartyl próteasi hemjari af nýjum flokki súlfonamíða |
| US5434265A (en) * | 1992-12-22 | 1995-07-18 | Eli Lilly And Company | Inhibitors of HIV protease |
| US5484926A (en) * | 1993-10-07 | 1996-01-16 | Agouron Pharmaceuticals, Inc. | HIV protease inhibitors |
| US5527829A (en) * | 1994-05-23 | 1996-06-18 | Agouron Pharmaceuticals, Inc. | HIV protease inhibitors |
-
1996
- 1996-09-05 US US08/708,607 patent/US5705647A/en not_active Expired - Fee Related
-
1997
- 1997-09-02 ZA ZA9707868A patent/ZA977868B/xx unknown
- 1997-09-02 IN IN1611CA1997 patent/IN183739B/en unknown
- 1997-09-04 EP EP97940770A patent/EP0931071B1/en not_active Expired - Lifetime
- 1997-09-04 ES ES97940770T patent/ES2306461T3/es not_active Expired - Lifetime
- 1997-09-04 AU AU42470/97A patent/AU4247097A/en not_active Abandoned
- 1997-09-04 CO CO97051480A patent/CO4900044A1/es unknown
- 1997-09-04 CA CA002264725A patent/CA2264725A1/en not_active Abandoned
- 1997-09-04 AT AT97940770T patent/ATE397591T1/de not_active IP Right Cessation
- 1997-09-04 AR ARP970104038A patent/AR009532A1/es active IP Right Grant
- 1997-09-04 WO PCT/US1997/015469 patent/WO1998009952A1/en active Application Filing
- 1997-09-04 JP JP10512832A patent/JP2001501183A/ja not_active Ceased
- 1997-09-04 DE DE69738751T patent/DE69738751D1/de not_active Expired - Fee Related
- 1997-09-05 UY UY24697A patent/UY24697A1/es not_active IP Right Cessation
- 1997-09-05 MY MYPI97004132A patent/MY132553A/en unknown
- 1997-09-05 ID IDP973109A patent/ID17012A/id unknown
-
2008
- 2008-08-25 JP JP2008215289A patent/JP2009040788A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| UY24697A1 (es) | 1997-10-21 |
| ZA977868B (en) | 1998-03-30 |
| EP0931071A1 (en) | 1999-07-28 |
| ATE397591T1 (de) | 2008-06-15 |
| ES2306461T3 (es) | 2008-11-01 |
| EP0931071B1 (en) | 2008-06-04 |
| MY132553A (en) | 2007-10-31 |
| AU4247097A (en) | 1998-03-26 |
| JP2001501183A (ja) | 2001-01-30 |
| ID17012A (id) | 1997-11-27 |
| JP2009040788A (ja) | 2009-02-26 |
| CO4900044A1 (es) | 2000-03-27 |
| IN183739B (es) | 2000-04-01 |
| DE69738751D1 (de) | 2008-07-17 |
| US5705647A (en) | 1998-01-06 |
| CA2264725A1 (en) | 1998-03-12 |
| WO1998009952A1 (en) | 1998-03-12 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NO974572D0 (no) | Cyklodextrin-forbindelser, fremgangsmåter for fremstilling og anvendelse derav | |
| NO20012158D0 (no) | Substituerte 2-fenylbenzimidazoler, fremgangsmåte til fremstilling og anvendelse derav | |
| DK0985697T3 (da) | Oxiranderivater og fremgangsmåde til fremstilling deraf | |
| EE200300169A (et) | Tsüklooksügenaas-2 inhibiitorite kasutamise meetod südame-veresoonkonna haiguste ärahoidmiseks | |
| NO20012865L (no) | Fremgangsmåter og utstyr for profilering og skjöting av rör | |
| ATE222240T1 (de) | Hiv - protease inhibitoren | |
| NO984107L (no) | Kappa-agonist-forbindelser og farmas°ytiske preparater derav | |
| EE03855B1 (et) | Alfusosiinhüdrokloriidi reguleeritult vabastav tablett | |
| NO996352D0 (no) | <Kappa>-antagenist-forbindelser, farmasoeytiske sammensetninger og fremgangsmåte for forebygging og behandling av pruritus | |
| NO985329D0 (no) | FremgangsmÕte for Õ fremstille koplymerer og blandinger inneholdende det samme | |
| DK0719788T3 (da) | Fremgangsmåde til fremstilling af 1-(2'-deoxy-2',2'-difluor-D-ribofuranosyl)-4-aminopyrimidin-2-on-hydrochlorid | |
| MX202260B (es) | Procedimiento para la obtencion de aminas y aminonitrilos. | |
| NO891878L (no) | Fremgangsmaate og anordning for foring av roerledninger. | |
| EE9900196A (et) | Bensüüleetrite valmistamise protsess | |
| AR009532A1 (es) | COMPUESTOS INTERMEDIARIOS DE SíNTESIS DE INHIBIDORES DE VIH-PROTEASA, MÉTODOS PARA SU PREPARACIoN Y UN PROCESO DE ELABORACIoN DE MESILATO DE NELFINAVIR | |
| NO973263D0 (no) | Fremgangsmåte for fremstilling og anvendelse av vandige emulsjoner | |
| NO985965L (no) | Verkt°y, r°r og fremgangsmÕte for tilforming av r°ret | |
| DK0828019T3 (da) | Sammensat vlies, fremgangsmåde til dens fremstilling og anvendelse deraf | |
| DK0824517T3 (da) | Fremgangsmåde til fremstilling af lercanidipinhydrochlorid | |
| DK1003383T4 (da) | Smagsforstærkende N-ethyl-p-menthan-3-carboxamidindeholdende forbindelser og fremgangsmåde til fremstilling og anvendelse deraf | |
| IS5035A (is) | Aðferðir til varnar gegn brjóstakrabbameini | |
| DK0834255T3 (da) | Fremgangsmåde til fremstilling af et aromastof til drikkevarer | |
| NO940801L (no) | Fremgangsmåte og komponenter for alternativ forskaling | |
| NO990913L (no) | Naftylforbindelser, intermediater, sammensetninger og metoder for anvendelse | |
| DK0946514T3 (da) | Fremgangsmåde til fremstilling af n-substituerede 3-hydroxypyrazoler |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant, registration |